Patents by Inventor Frédéric SIMONIN

Frédéric SIMONIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PAIN
    Publication number: 20210221784
    Abstract: The invention relates to compounds, pyridine derivatives, and pharmaceutical 10 compositions containing same for use in the treatment of pain. It also relates to specific compounds, compositions comprising the same and uses thereof, in particular in the treatment of pain.
    Type: Application
    Filed: February 5, 2019
    Publication date: July 22, 2021
    Applicants: Université de Strasbourg, Centre National de la Recherche Scientifique
    Inventors: Martine SCHMITT, Jacques BRICARD, Frédéric SIMONIN, Jean-Jacques BOURGUIGNON, Frédéric BIHEL, Khadija ELHABAZI
  • Pyrimidinone derivatives and uses thereof to neutralize the biological activity of chemokines
    Patent number: 11046657
    Abstract: A subject of the present invention is a compound having the general formula (I): a pharmaceutically acceptable salt thereof or a tautomeric form thereof, wherein A, B3, B4, B5, Y, X, B1 and B2 are as defined in any one of claims 1 to 10. Another subject of the invention is the compound as defined above for use as a medicament, in particular for preventing and/or treating inflammation and inflammatory diseases, immune and auto-immune diseases, pain related diseases, genetic diseases and/or cancer.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: June 29, 2021
    Assignees: Centre National de la Recherche Scientifique, Institut National de la Sante et de la Recherche Medicale, Universite de Strasbourg, Universite Paris-Sud, Centre International de Recherche aux Frontieres de la Chimie
    Inventors: Dominique Bonnet, Nelly Frossard, Jean-Luc Galzi, Christophe Guignabert, Marcel Hibert, Frédéric Simonin, Sylviane Muller
  • HYBRID MU OPIOID RECEPTOR AND NEUROPEPTIDE FF RECEPTOR BINDING MOLECULES, THEIR METHODS OF PREPARATION AND APPLICATIONS IN THERAPEUTIC TREATMENT
    Publication number: 20210002231
    Abstract: Molecules binding the mu opioid receptor (MOR) and the neuropeptide FF receptor (NPFFR), in particular molecules having a MOR agonist and NPFFR modulatory activity, and pharmaceutical compositions useful in the treatment of pain and/or hyperalgesia.
    Type: Application
    Filed: March 11, 2019
    Publication date: January 7, 2021
    Inventors: Frédéric Simonin, Armand Drieu la Rochelle, Frédéric Bihel, Steven Ballet
  • Pyrimidinone Derivatives and Uses Thereof to Neutralize the Biological Activity of Chemokines
    Publication number: 20200181093
    Abstract: A subject of the present invention is a compound having the general formula (I): a pharmaceutically acceptable salt thereof or a tautomeric form thereof, wherein A, B3, B4, B5, Y, X, B1 and B2 are as defined in any one of claims 1 to 10. Another subject of the invention is the compound as defined above for use as a medicament, in particular for preventing and/or treating inflammation and inflammatory diseases, immune and auto-immune diseases, pain related diseases, genetic diseases and/or cancer.
    Type: Application
    Filed: July 13, 2017
    Publication date: June 11, 2020
    Applicants: Centre National de la Recherche Scientifique (CNRS, Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Strasbourg, Universite Paris-Sud, Centre International de Recherche aux Frontieres d e la Chimie
    Inventors: Dominique Bonnet, Nelly Frossard, Jean-Luc Galzi, Christophe Guignabert, Marcel Hibert, Frédéric Simonin, Sylviane Muller
  • METABOLICALLY STABLE SPEXIN PEPTIDE ANALOGS
    Publication number: 20190135887
    Abstract: The present invention concerns metabolically stable and non-immunogen spexin analogs that are completely hydrosoluble at physiological pH, and their use for the prevention or the treatment of diseases mediated by the GALR2 receptor.
    Type: Application
    Filed: June 16, 2017
    Publication date: May 9, 2019
    Inventors: Dominique BONNET, Frédéric SIMONIN, Glenn-Marie LE COZ, Lucie ESTÉOULLE
  • Human kappa opioid receptor, nucleic acids and uses thereof
    Patent number: 6146835
    Abstract: Novel peptides having human kappa opioid receptor activity, genetic material for expressing same, any recombinant cell expressing said polypeptides, and use thereof.
    Type: Grant
    Filed: February 11, 1997
    Date of Patent: November 14, 2000
    Assignee: Universite Louis Pasteur
    Inventors: Brigitte Kieffer, Frederic Simonin