Patents by Inventor Frédéric Van Gool

Frédéric Van Gool has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR MODIFYING REGULATORY T CELLS
    Publication number: 20210340496
    Abstract: Provided herein are compositions and methods for modifying regulatory T cells. The inventors have identified nuclear factors that influence expression of Foxp3, a key transcriptional regulator of Treg cells. Treg cells can be modified by inhibiting and/or overexpressing one or more of these nuclear factors to produce stabilized Treg cells or destabilized Treg cells.
    Type: Application
    Filed: October 10, 2019
    Publication date: November 4, 2021
    Applicant: The Regents of the University of California
    Inventors: Alexander Marson, Jessica T. Cortez, Jeffrey A. Bluestone, Eric Shifrut, Frederic Van Gool
  • PROPHYLACTIC AND THERAPEUTIC USE OF SIRTUIN INHIBITORS IN TNF-ALPHA MEDIATED PATHOLOGIES
    Publication number: 20100137345
    Abstract: The invention relates to the use of sirtuin inhibitors for reducing TNF-alpha production by cells and organisms. The invention also concerns prophylactic and therapeutic applications of sirtuin inhibitors in TNF-alpha mediated pathologies, such as various inflammatory and autoimmune disorders.
    Type: Application
    Filed: May 14, 2008
    Publication date: June 3, 2010
    Applicant: Universite Libre de Bruxelles
    Inventors: Oberdan Leo, Mara Galli, Frédéric Van Gool
  • NEW METHOD FOR THE TREATMENT OF INFLAMMATORY DISEASES
    Publication number: 20090325923
    Abstract: The present invention relates to the use of an inhibitor of the formation of nicotinamide adenyl dinucleotide for the preparation of a medicament used in the treatment of inflammatory diseases such as rheumatoid arthritis and endotoxemia.
    Type: Application
    Filed: September 3, 2007
    Publication date: December 31, 2009
    Applicant: TOPOTARGET SWITZERLAND SA
    Inventors: Oberdan Leo, Thibaut De Smedt, Frederic Van Gool, Mara Galli