Patents by Inventor Fran.cedilla.ois Clavel

Fran.cedilla.ois Clavel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for the preparation of human immunodeficiency virus type 2 (HIV-2) and antigens encoped thereby
    Patent number: 6037165
    Abstract: Methods for producing the newly discovered HIV-2 retrovirus and its antigens are provided. The antigens are obtained from various HIV-2 retroviruses. The antigen compositions comprise a lysate of an HIV-2 retrovirus, a protein of an HIV-2 retrovirus, or a glycoprotein of an HIV-2 retrovirus. Specifically, the antigen composition can comprise p12, p16, p26, gp32, gp42, and gp140.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: March 14, 2000
    Assignee: Institut Pasteur
    Inventors: Luc Montagnier, Solange Chamaret, Denise Guetard, Marc Alizon, Fran.cedilla.ois Clavel, Mireille Guyader, Pierre Sonigo, Fran.cedilla.oise Brun-Vezinet, Marianne Rey, Christine Rouzioux, Christine Katlama
  • Nucleic acids and pepties of human immunodeficiency virus type-1 (HIV-1).
    Patent number: 5843638
    Abstract: This invention is directed to nucleic acids derived from the pol region of the genome of human immunodeficiency virus type 1 (HIV-1). The nucleic acids are useful as probes for the detection of HIV-1. More particularly, this invention is directed to nucleic acids encoding a pol region of HIV-1 extending from about nucleotide 1856 to about 1906 and extending from about nucleotide 2048 to about nucleotide 2797.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 1, 1998
    Assignee: Institut Pasteur and Centre National de la Recherche Scientifique
    Inventors: Luc Montagnier, Bernard Krust, Solange Chamaret, Fran.cedilla.ois Clavel, Jean-Claude Chermann, Fran.cedilla.oise Barre-Sinoussi, Marc Alizon, Pierre Sonigo, Stewart Cole, Olivier Danos, Simon Wain-Hobson
  • In vitro diagnostic assays for the detection of HIV-1 or HIV-2 employing viral-specific antigens and antibodies
    Patent number: 5830641
    Abstract: The invention relates to a new class of retroviruses, designated by HIV-2, of which samples have been deposited to the ECACC under numbers 87.01.1001 and 87.01.1002 and to the NCIB under numbers 12.398 and 12.399.It relates also to antigens capable to be obtained from this virus, particularly proteins p12, p16, p26 and gp140. These various antigens can be used for the diagnosis of the disease, especially by contacting these antigens with a serum of a patient submitted to the diagnosis.It relates to immunogenic compositions containing more particularly the glycoprotein gp140. Finally it concerns nucleotidic sequences, which can be used especially as hybridization probes, derived from the RNA of HIV-2.
    Type: Grant
    Filed: March 17, 1994
    Date of Patent: November 3, 1998
    Assignee: Institut Pasteur
    Inventors: Luc Montagnier, Denise Guetard, Marc Alizon, Fran.cedilla.ois Clavel, Mireille Guyader, Pierre Sonigo
  • Hybrid cell line formed between T4 lymphocytes and tumoral lymphoid type cells
    Patent number: 5550052
    Abstract: The invention relates to new purified antigens of the LAV virus. They have molecular weights of about 135,000 and 150,000 daltons. They are useful for the detection of LAV antibodies in human sera. They are produced by hybrid cell-lines resulting from the fusion of T4 lymphocytes and cells of the MOLT-4 cell line.
    Type: Grant
    Filed: September 11, 1992
    Date of Patent: August 27, 1996
    Assignees: Institut Pasteur, Centre National de la Recherche Scientifique
    Inventors: Luc Montagnier, Fran.cedilla.oise Rey, Bernard Krust, Fran.cedilla.ois Clavel