Patents by Inventor Fran.cedilla.ois Tillequin

Fran.cedilla.ois Tillequin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prodrugs, their preparation and use as pharmaceuticals
    Patent number: 6146658
    Abstract: Glycosyl-spacer-drugs compounds (prodrugs), their preparation and their use as pharmaceuticals are described.
    Type: Grant
    Filed: May 20, 1997
    Date of Patent: November 14, 2000
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Klaus Bosslet, Jorg Czech, Dieter Hoffmann, Cenek Kolar, Fran.cedilla.ois Tillequin, Jean-Claude Florent, Michel Azoulay, Claude Monneret, Jean-Claude Jacquesy, Jean-Pierre Gesson, Michel Koch
  • Prodrugs their preparation and use as pharmaceuticals
    Patent number: 5955100
    Abstract: Glycosyl-spacer-drugs compounds (prodrugs), their preparation and their use as pharmaceuticals are described.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: September 21, 1999
    Assignees: Behringwerke Aktiengesellschaft, Laboratories Hoechst S/A
    Inventors: Klaus Bosslet, Jorg Czech, Dieter Hoffmann, Cenek Kolar, Fran.cedilla.ois Tillequin, Jean-Claude Florent, Michel Azoulay, Claude Monneret, Jean-Claude Jacquesy, Jean-Pierre Gesson, Michel Koch
  • Pro-prodrugs, their production and use
    Patent number: 5877158
    Abstract: Substrate-spacer-prodrug compounds (pro-prodrugs) suited for site specific delivery of drugs, a process of preparing them and their use are described.
    Type: Grant
    Filed: September 20, 1994
    Date of Patent: March 2, 1999
    Assignees: Behringwerke Aktiengesellschaft, Laboratoires Hoechst S/A
    Inventors: Klaus Bosslet, Jorg Czech, Dieter Hoffmann, Fran.cedilla.ois Tillequin, Jean-Claude Florent, Michel Azoulay, Claude Monneret, Jean-Claude Jacquesy, Jean-Pierre Gesson, Michel Koch
  • Prodrugs for enzyme mediated activation
    Patent number: 5621002
    Abstract: Enzymatically clearable prodrugs with reduced Michaelis-Menten constant (Km) are described.
    Type: Grant
    Filed: September 9, 1994
    Date of Patent: April 15, 1997
    Assignees: Behringwerke Aktiengesellschaft, Laboratoires Hoechst S/A
    Inventors: Klaus Bosslet, J org Czech, Dieter Hoffmann, Andrea Vasella, Roland Hoos, Fran.cedilla.ois Tillequin, Jean-Claude Florent, Michel Azoulay, Claude Monneret, Jean-Claude Jacquesy, Jean-Pierre Gesson, Michel Koch
  • Acronycine analogues
    Patent number: 5567707
    Abstract: Compounds of formula (I): ##STR1## wherein R.sub.3, R.sub.4, R.sub.5, R.sub.6, X and Y are defined in the description.Those compounds are used therapeutically in the treatment of cancerous tumours.
    Type: Grant
    Filed: February 16, 1995
    Date of Patent: October 22, 1996
    Assignee: Adir et Compagnie
    Inventors: Michel Koch, Fran.cedilla.ois Tillequin, Alexios-Leandros Skaltsounis, Yves Rolland, Alain Pierre, Ghanem Atassi
  • Glycosylated prodrugs, their method of preparation and their uses
    Patent number: 5561119
    Abstract: Glycosylated prodrugs, a preparation method therefor, and their use with tumor-specific immunoenzymatic conjugates for the treatment of cancer, are described. These anthracycline prodrugs have formula (I).
    Type: Grant
    Filed: May 27, 1994
    Date of Patent: October 1, 1996
    Assignees: Laboratoires Hoechst, Behringwerke A.G.
    Inventors: Jean-Claude Jacquesy, Jean-Pierre Gesson, Claude Monneret, Martine Mondon, Brigitte Renoux, Jean-Claude Florent, Michel Koch, Fran.cedilla.ois Tillequin, Hans H. Sedlacek, Manfred Gerken, Cenek Kolar, Gilbert Gaudel, Klaus Bosslet, J org Czech, Dieter Hoffman, Gerhard Seemann, Hans-Ulrich Schorlemmer, Gerhard Dickneite