Patents by Inventor François Barthelat

François Barthelat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200268617
    Abstract: The present disclosure concerns a mineralized tissue adhesive or filler composition comprising an intermolecular crosslinked osteopontin protein for treating an exposed surface of a mineralized tissue. The mineralized tissue adhesive or filler composition can be added directly on the exposed surface of the mineralized tissue or on a layer of monodisperse OPN protein which has been deposited on the exposed surface of the mineralized tissue. The present disclosure also includes methods and kits of using the mineralized tissue adhesive or filler composition especially in dental applications. The present application also provides dental coatings, fillings, bondings and veneers comprising the mineralized tissue adhesive or filler composition described herein.
    Type: Application
    Filed: February 17, 2020
    Publication date: August 27, 2020
    Inventors: François BARTHELAT, Sacha CAVELIER, Ahmad KHAYER DASTJERDI TOROGHI, Marc D. MCKEE
  • Patent number: 10376611
    Abstract: A synthetic bone graft is described which is adapted to be received within a bone defect and which is structurally load-bearing. The bone graft comprises an entirely synthetic graft body corresponding in shape and size to the bone defect. The graft body is composed of a plurality of superimposed multilayered structures, each of the multilayered structures having a biopolymer layer joined to a biomineral layer to define an interface therebetween. The biomineral layer has a stiffness that is greater than that of the biopolymer layer, and the biopolymer layer has a toughness that is less than that of the biomineral layer.
    Type: Grant
    Filed: February 16, 2016
    Date of Patent: August 13, 2019
    Assignee: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: Francois Barthelat, Michael Tanzer, Sacha Cavelier
  • Patent number: 10329194
    Abstract: Highly mineralized natural materials often boast unusual combinations of stiffness, strength and toughness currently unmatched by today's engineering materials. Beneficially, according to the embodiments of the invention, these unusual combinations can be introduced into ceramics, glasses, and crystal materials, for example by the introduction of patterns of weaker interfaces with simple or intricate architectures, which channel propagating cracks into toughening configurations. Further, such deliberately-introduced weaker interfaces, such as exploiting three-dimensional arrays of laser-generated microcracks, can deflect and guide larger incoming cracks. Addition of interlocking interfaces and flexible materials provide further energy dissipation and toughening mechanism, by channeling cracks into interlocking configurations and ligament-like pullout mechanisms. Such biomimetic materials, based on carefully architectured interfaces, provide a new pathway to toughening hard and brittle materials.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: June 25, 2019
    Assignee: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: Francois Barthelat, Seyed Mohammad Mirkhalaf Valashani, Ahmad Khayer Dastjerdi
  • Publication number: 20170197873
    Abstract: Natural materials often boast unusual combinations of stiffness, strength and toughness currently unmatched by today's engineering materials. Beneficially, according to the embodiments of the invention, these unusual combinations can be introduced into ceramics, glasses, and crystal materials, for example by the introduction of patterns of weaker interfaces with simple or intricate architectures. Two-dimensional surface modifications and three-dimensional arrays of effects within these materials allow for the deformation of these materials for increased flexure, impact resistance, etc. Further, the addition of interlocking substrate blocks in isolation or with additional flexible materials provide for improved energy dissipation and toughening. Such modified materials, based on carefully architectured interfaces, provide a new pathway to toughening hard and brittle materials.
    Type: Application
    Filed: June 8, 2015
    Publication date: July 13, 2017
    Applicant: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: François BARTHELAT, Seyed Mohammad Mirkhalaf VALASHANI, Ahmad Khayer DASTJERDI
  • Publication number: 20160235536
    Abstract: A synthetic bone graft is described which is adapted to be received within a bone defect and which is structurally load-bearing. The bone graft comprises an entirely synthetic graft body corresponding in shape and size to the bone defect. The graft body is composed of a plurality of superimposed multilayered structures, each of the multilayered structures having a biopolymer layer joined to a biomineral layer to define an interface therebetween. The biomineral layer has a stiffness that is greater than that of the biopolymer layer, and the biopolymer layer has a toughness that is less than that of the biomineral layer.
    Type: Application
    Filed: February 16, 2016
    Publication date: August 18, 2016
    Inventors: Francois BARTHELAT, Michael TANZER, Sacha CAVELIER
  • Publication number: 20150274587
    Abstract: Highly mineralized natural materials often boast unusual combinations of stiffness, strength and toughness currently unmatched by today's engineering materials. Beneficially, according to the embodiments of the invention, these unusual combinations can be introduced into ceramics, glasses, and crystal materials, for example by the introduction of patterns of weaker interfaces with simple or intricate architectures, which channel propagating cracks into toughening configurations. Further, such deliberately-introduced weaker interfaces, such as exploiting three-dimensional arrays of laser-generated microcracks, can deflect and guide larger incoming cracks. Addition of interlocking interfaces and flexible materials provide further energy dissipation and toughening mechanism, by channeling cracks into interlocking configurations and ligament-like pullout mechanisms. Such biomimetic materials, based on carefully architectured interfaces, provide a new pathway to toughening hard and brittle materials.
    Type: Application
    Filed: February 27, 2015
    Publication date: October 1, 2015
    Inventors: FRANCOIS BARTHELAT, SEYED MOHAMMAD MIRKHALAF VALASHANI, AHMAD KHAYER DASTJERDI
  • Patent number: 8176705
    Abstract: The present invention relates to a novel composite structure with enhanced toughness, which incorporates features mimicked from nacre (mother of pearl). The structure can be used in many industrial and clinical applications, including aeronautics (aircraft skin), the defense industry (armor materials); orthopedics and medical devices (tough, biocompatible coatings on prostheses) and micro-electro-mechanical systems (MEMS; increased reliability for critical components).
    Type: Grant
    Filed: October 30, 2011
    Date of Patent: May 15, 2012
    Assignee: Northwestern University
    Inventors: Horacio Dante Espinosa, François Barthelat
  • Publication number: 20120067519
    Abstract: The present invention relates to a novel composite structure with enhanced toughness, which incorporates features mimicked from nacre (mother of pearl). The structure can be used in many industrial and clinical applications, including aeronautics (aircraft skin), the defense industry (armor materials); orthopedics and medical devices (tough, biocompatible coatings on prostheses) and micro-electro-mechanical systems (MEMS; increased reliability for critical components).
    Type: Application
    Filed: October 30, 2011
    Publication date: March 22, 2012
    Inventors: Horacio Dante Espinosa, Francois Barthelat
  • Patent number: 8067078
    Abstract: The present invention relates to a novel composite structure with enhanced toughness, which incorporates features mimicked from nacre (mother of pearl). The structure can be used in many industrial and clinical applications, including aeronautics (aircraft skin), the defense industry (armor materials); orthopedics and medical devices (tough, biocompatible coatings on prostheses) and micro-electro-mechanical systems (MEMS; increased reliability for critical components).
    Type: Grant
    Filed: November 13, 2007
    Date of Patent: November 29, 2011
    Assignee: Northwestern University
    Inventors: Horacio Dante Espinosa, François Barthelat