Patents by Inventor François-René ALEXANDRE

François-René ALEXANDRE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENANTIOMERICALLY PURE PHOSPHOINDOLES AS HIV INHIBITORS
    Publication number: 20110257129
    Abstract: 3-phosphoindole compounds substantially in the form of a single enantiomer useful for the treatment of Flaviviridae virus infections, and particularly for HIV infections are provided. Also provided are pharmaceutical compositions comprising the 3-phosphoindole compounds alone or in combination with one or more other anti-viral agents, processes for their preparation, and methods of manufacturing a medicament incorporating these compounds.
    Type: Application
    Filed: June 2, 2011
    Publication date: October 20, 2011
    Inventors: Richard Storer, Francois-Rene Alexandre, Cyril Dousson, Adel M. Moussa, Edward Bridges, Alistair Stewart, Jing Yang Wang, Benjamin Alexander Mayes
  • Macrocyclic serine protease inhibitors
    Patent number: 8003659
    Abstract: Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula I, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Grant
    Filed: February 3, 2009
    Date of Patent: August 23, 2011
    Assignee: Indenix Pharmaceuticals, Inc.
    Inventors: Christophe Claude Parsy, Francois-Rene Alexandre, Dominique Surleraux, Michel Derock, Frederic Leroy
  • 5,5-FUSED ARYLENE OR HETEROARYLENE HEPATITIS C VIRUS INHIBITORS
    Publication number: 20110150827
    Abstract: Provided herein are 5,5-fused heteroarylene hepatitis C virus inhibitor compounds, for example, of Formula I, IA, or IB, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Application
    Filed: December 17, 2010
    Publication date: June 23, 2011
    Applicant: Idenix Pharmaceuticals, Inc.
    Inventors: Cyril B. Dousson, David Dukhan, Christophe Claude Parsy, Claire Pierra, Francois-Rene Alexandre, Guillaume Brandt, Daniel Da Costa, Houcine Rahali, Jean-Laurent Paparin, Michel Derock, Thierry Convard, Dominique Surleraux
  • Enantiomerically pure phosphoindoles as HIV inhibitors
    Patent number: 7960428
    Abstract: 3-phosphoindole compounds substantially in the form of a single enantiomer useful for the treatment of Flaviviridae virus infections, and particularly for HIV infections are provided. Also provided are pharmaceutical compositions comprising the 3-phosphoindole compounds alone or in combination with one or more other anti-viral agents, processes for their preparation, and methods of manufacturing a medicament incorporating these compounds.
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: June 14, 2011
    Assignee: Idenix Pharmaceuticals, Inc.
    Inventors: Richard Storer, Francois-Rene Alexandre, Cyril Dousson, Adel M. Moussa, Edward Bridges, Alistair Stewart, Jing Yang Wang, Benjamin Alexander Mayes
  • MACROCYCLIC SERINE PROTEASE INHIBITORS
    Publication number: 20110129443
    Abstract: Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula Ia or Ib, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Application
    Filed: August 4, 2010
    Publication date: June 2, 2011
    Applicant: Idenix Pharmaceuticals, Inc.
    Inventors: Christophe Claude Parsy, Francois-Rene Alexandre, Frederic Leroy, Thierry Convard, Dominique Surleraux
  • MACROCYCLIC SERINE PROTEASE INHIBITORS
    Publication number: 20100260710
    Abstract: Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula Ia or Ib, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Application
    Filed: April 7, 2010
    Publication date: October 14, 2010
    Applicant: Idenix Pharmaceuticals, Inc.
    Inventors: Christophe Claude Parsy, Francois-Rene Alexandre, Michel Derock, Frederic Leroy, Jean-Christophe Meillon, Thierry Convard, Dominique Surleraux
  • MACROCYCLIC SERINE PROTEASE INHIBITORS
    Publication number: 20100016578
    Abstract: Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula I, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Application
    Filed: September 18, 2009
    Publication date: January 21, 2010
    Applicant: Idenix Pharmaceuticals, Inc.
    Inventors: Christophe Claude Parsy, Francois-Rene Alexandre, Dominique Surleraux, Michel Derock, Frederic Leroy
  • MACROCYCLIC SERINE PROTEASE INHIBITORS
    Publication number: 20090202480
    Abstract: Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula I, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Application
    Filed: February 3, 2009
    Publication date: August 13, 2009
    Applicant: Idenix Pharmaceuticals, Inc.
    Inventors: Christophe Claude Parsy, Francois-Rene Alexandre, Dominique Surleraux, Michel Derock, Frederic Leroy
  • PHOSPHO-INDOLES AS HIV INHIBITORS
    Publication number: 20090163444
    Abstract: 3-phosphoindole compounds for the treatment of retroviral infections, and particularly for HIV, are described. Also included are compositions comprising the 3-phosphoindole derivatives alone or in combination with one or more other anti-retroviral agents, processes for their preparation, and methods of manufacturing a medicament incorporating these compounds.
    Type: Application
    Filed: November 21, 2008
    Publication date: June 25, 2009
    Inventors: Richard Storer, Cyril Dousson, Francois-Rene Alexandre, Arlene Roland
  • Phospho-indoles as HIV inhibitors
    Patent number: 7534809
    Abstract: 3-phosphoindole compounds for the treatment of retroviral infections, and particularly for HIV, are described. Also included are compositions comprising the 3-phosphoindole derivatives alone or in combination with one or more other anti-retroviral agents, processes for their preparation, and methods of manufacturing a medicament incorporating these compounds.
    Type: Grant
    Filed: September 16, 2005
    Date of Patent: May 19, 2009
    Assignee: Idenix Pharmaceuticals, Inc.
    Inventors: Richard Storer, Cyril Dousson, Francois-Rene Alexandre, Arlene Roland
  • MACROCYCLIC SERINE PROTEASE INHIBITORS I
    Publication number: 20090047244
    Abstract: Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula I, pharmaceutical compositions comprising such compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof.
    Type: Application
    Filed: July 25, 2008
    Publication date: February 19, 2009
    Applicant: Idenix Pharmaceuticals, Inc.
    Inventors: Christophe Claude Parsy, Dominique Surleraux, Francois-Rene Alexandre, Michel Derock, Frederic Leroy
  • Enantiomerically pure phosphoindoles as HIV inhibitors
    Publication number: 20080213217
    Abstract: 3-phosphoindole compounds substantially in the form of a single enantiomer useful for the treatment of Flaviviridae virus infections, and particularly for HIV infections are provided. Also provided are pharmaceutical compositions comprising the 3-phosphoindole compounds alone or in combination with one or more other anti-viral agents, processes for their preparation, and methods of manufacturing a medicament incorporating these compounds.
    Type: Application
    Filed: September 28, 2007
    Publication date: September 4, 2008
    Inventors: Richard Storer, Francois-Rene Alexandre, Cyril Dousson, Adel M. Moussa, Edward Bridges, Alistair Stewart, Jing Yang Wang, Benjamin Alexander Mayes
  • Phospho-indoles as HIV inhibitors
    Publication number: 20060074054
    Abstract: 3-phosphoindole compounds for the treatment of retroviral infections, and particularly for HIV, are described. Also included are compositions comprising the 3-phosphoindole derivatives alone or in combination with one or more other anti-retroviral agents, processes for their preparation, and methods of manufacturing a medicament incorporating these compounds.
    Type: Application
    Filed: September 16, 2005
    Publication date: April 6, 2006
    Inventors: Richard Storer, Cyril Dousson, Francois-Rene Alexandre, Arlene Roland