Patent number: 7405309
Abstract: The invention relates to pyranone derivatives of general formula (I), wherein X is chlorine, bromine or iodine and R1 and R2 is independently a hydrogen atom, an alkyl, cycloalkyl or alkylene, linear or branched group containing 1-20 carbon atoms, optionally substituted by a hydroxyl, amino, ether or halogen group, or R1 and R2 form together a cycle of 5, 6, 7 or 8 members which is optionally substituted by a hydroxyl, amino, ether or halogen group including isomers, enantiomers, diastereoisomers and the mixtures thereof. A method for preparing the inventive derivatives and the therapeutic use thereof, in particular for treating cancer, are also disclosed.
Type:
Grant
Filed:
January 14, 2005
Date of Patent:
July 29, 2008
Assignee:
Centre National de la Recherche Scientifique (CNRS)
Inventors:
Joanna Bakala, Denyse Herlem, Emile Benechie, Jérôme Bignon, Françoise Khuong-Huu, Guy Jean Marie Potier, legal representative, Marie-Claude Denise Michèle Zelveyan, legal representative, Catherine Marie Germaine Magnan, legal representative, Odette Drion, legal representative, Pierre Potier