Patent number: 7235532
Abstract: The present invention relates to the use of a compound of formula I: in which, A1 is the radical corresponding to D- or L-Ser, A2 is the radical corresponding to D- or L-Asp or Glu, A3 is the radical corresponding to D- or L-Lys, Arg or Gm, A4 is the radical corresponding to D- or L-Pro, R1 and R2 are chosen, independently, from H, C1–C12-alkyl which may or may not be substituted, C7–C20-arylalkyl which may or may not be substituted, R4CO or R4COO, R4 being C1–C12-alkyl which may or may not be substituted, or C7–C20-arylalkyl which may or may not be substituted; among the substitutions, mention should be made of OH, NH2 or COOH, X1 and X2 are peptide or pseudopeptide bonds, X3 is CO or CH2 and R3 is OH, NH2, C1–C1-alkoxy or NH-X4-CH2-Z, X4 is a normal or branched C1–C12 hydrocarbon, and Z is H, OH, CO2H or CONH2, or the corresponding tripeptides comprising the radicals A1, A2, A3, and also the pharmacautically acceptable salts, for the preparation of a medicament for treating pathologies which may benef
Type:
Grant
Filed:
September 20, 2001
Date of Patent:
June 26, 2007
Assignee:
Centre National de la Recherche Scientfique
Inventors:
Joanna Bakala, Jean-Paul Pierre Potier, Françoise Lawrence, Nathalie Cheviron, Jérôme Bignon, Yves Fromes
