Patents by Inventor Frances A. Shepherd

Frances A. Shepherd has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF TREATING LUNG CANCER BY VACCINATION WITH MUC-1 LIPOPEPTIDE
    Publication number: 20160067322
    Abstract: The invention is directed to the treatment of lung cancer, preferably non-small cell lung cancer (NSCLC) by means of a combination therapy comprising concurrent chemo-radiotherapy followed by vaccination with a muc-1 lipopetide. The therapy elicits prolonged survival rates compared to a respective therapy including sequential chemo-radiotherapy.
    Type: Application
    Filed: April 14, 2014
    Publication date: March 10, 2016
    Applicant: MERCK PATENT GmbH
    Inventors: Andreas SCHROEDER, Christoph HELWIG, Anja-Helena LOOS, Armin SCHUELER, Martin FALK, Charles BUTTS, Frances A. SHEPHERD
  • PROGNOSTIC AND PREDICTIVE GENE SIGNATURE FOR NON-SMALL CELL LUNG CANCER AND ADJUVANT CHEMOTHERAPY
    Publication number: 20160032407
    Abstract: The application provides methods of prognosing and classifying lung cancer patients into poor survival groups or good survival groups and for determining the benefit of adjuvant chemotherapy by way of a multigene signature. The application also includes kits and computer products for use in the methods of the application.
    Type: Application
    Filed: August 10, 2015
    Publication date: February 4, 2016
    Inventors: Ming-Sound Tsao, Frances A. Shepherd, Igor Jurisica, Sandy D. Der, Chang-Qi Zhu, Dan Strumpf, Lesley Seymour, Keyue Ding
  • Prognostic and Predictive Gene Signature for Non-Small Cell Lung Cancer and Adjuvant Chemotherapy
    Publication number: 20160024596
    Abstract: The application provides methods of prognosing and classifying lung cancer patients into poor survival groups or good survival groups and for determining the benefit of adjuvant chemotherapy by way of a multigene signature. The application also includes kits and computer products for use in the methods of the application.
    Type: Application
    Filed: August 7, 2015
    Publication date: January 28, 2016
    Inventors: Ming-Sound Tsao, Frances A. Shepherd, Igor Jurisica, Sandy D. Der, Chang-Qi Zhu, Dan Strumpf, Lesley Seymour, Keyue Ding
  • PROGNOSTIC AND PREDICTIVE GENE SIGNATURE FOR NON-SMALL CELL LUNG CANCER AND ADJUVANT CHEMOTHERAPY
    Publication number: 20120323594
    Abstract: The application provides methods of prognosing and classifying lung cancer patients into poor survival groups or good survival groups and for determining the benefit of adjuvant chemotherapy by way of a multigene signature. The application also includes kits and computer products for use in the methods of the application.
    Type: Application
    Filed: May 15, 2012
    Publication date: December 20, 2012
    Inventors: Ming-Sound Tsao, Frances A. Shepherd, Igor Jurisica, Sandy D. Der, Chang-Qi Zhu, Dan Strumpf, Lesley Seymour, Keyue Ding
  • Prognostic and predictive gene signature for non-small cell lung cancer and adjuvant chemotherapy
    Patent number: 8211643
    Abstract: The application provides methods of prognosing and classifying lung cancer patients into poor survival groups or good survival groups and for determining the benefit of adjuvant chemotherapy by way of a multigene signature. The application also includes kits and computer products for use in the methods of the application.
    Type: Grant
    Filed: May 14, 2009
    Date of Patent: July 3, 2012
    Assignee: University Health Network
    Inventors: Ming-Sound Tsao, Frances A. Shepherd, Igor Jurisica, Sandy D. Der, Chang-Qi Zhu, Dan Strumpf, Lesley Seymour, Keyue Ding
  • METHODS AND COMPOSITIONS FOR LUNG CANCER PROGNOSIS
    Publication number: 20120141603
    Abstract: Disclosed herein are methods and materials for prognosing survival of lung cancer patients, the methods comprising the detection of gains and losses of minimal common regions and/or genes associated with prognosis and benefit of chemotherapy.
    Type: Application
    Filed: April 21, 2010
    Publication date: June 7, 2012
    Applicants: BRITISH COLUMBIA CANCER AGENCY BRANCH, UNIVERSITY HEALTH NETWORK
    Inventors: Ming-Sound Tsao, Kenneth Craddock, Wan Lam, Timon Buys, Igor Jurisica, Frances A. Shepherd
  • PROGNOSTIC GENE EXPRESSION SIGNATURE FOR SQUAMOUS CELL CARCINOMA OF THE LUNG
    Publication number: 20120100999
    Abstract: Provided is a gene expression signature consisting of 12 biomarkers for use in prognosing or classifying a subject with lung squamous cell carcinoma into a poor survival group or a good survival group. The 12-gene signature specific for squamous cell carcinoma consists of the biomarkers RPL22, VEGFA, G0S2, NES, TNFRSF25, DKFZP586P0123, COL8A2, ZNF3, PJPK5, RNFT2, ARHGEF12 and PTPN20A.
    Type: Application
    Filed: April 20, 2010
    Publication date: April 26, 2012
    Applicant: UNIVERSITY HEALTH NETWORK
    Inventors: Ming-Sound Tsao, Chang-Qi Zhu, Igor Jurisica, Sandy D. Der, Frances A. Shepherd
  • Materials and methods for prognosing lung cancer survival
    Patent number: 8026055
    Abstract: The invention provides methods of prognosing and classifying lung cancer patients into poor survival groups or good survival groups. The invention also includes kits for use in the methods of the invention.
    Type: Grant
    Filed: November 15, 2007
    Date of Patent: September 27, 2011
    Assignee: University Health Network
    Inventors: Ming Sound Tsao, Suzanne Lau, Paul Boutros, Melania Pintilie, Sandy Der, Frances A. Shepherd, Igor Jurisica, Linda Penn
  • PROGNOSTIC AND PREDICTIVE GENE SIGNATURE FOR NON-SMALL CELL LUNG CANCER AND ADJUVANT CHEMOTHERAPY
    Publication number: 20100184063
    Abstract: The application provides methods of prognosing and classifying lung cancer patients into poor survival groups or good survival groups and for determining the benefit of adjuvant chemotherapy by way of a multigene signature. The application also includes kits and computer products for use in the methods of the application.
    Type: Application
    Filed: January 8, 2010
    Publication date: July 22, 2010
    Inventors: Ming-Sound Tsao, Frances A. Shepherd, Igor Jurisica, Sandy D. Der, Chang-Qi Zhu, Dan Strumpf, Lesley Seymour, Keyue Ding
  • Prognostic and Predictive Gene Signature for Non-Small Cell Lung Cancer and Adjuvant Chemotherapy
    Publication number: 20090291448
    Abstract: The application provides methods of prognosing and classifying lung cancer patients into poor survival groups or good survival groups and for determining the benefit of adjuvant chemotherapy by way of a multigene signature. The application also includes kits and computer products for use in the methods of the application.
    Type: Application
    Filed: May 14, 2009
    Publication date: November 26, 2009
    Inventors: Igor Jurisica, Sandy D. Der, Ming-Sound Tsao, Frances A. Shepherd, Chang-Qi Zhu, Dan Strumpf, Lesley Seymour, Keyue Ding
  • MATERIALS AND METHODS FOR PROGNOSING LUNG CANCER SURVIVAL
    Publication number: 20080176236
    Abstract: The invention provides methods of prognosing and classifying lung cancer patients into poor survival groups or good survival groups. The invention also includes kits for use in the methods of the invention.
    Type: Application
    Filed: November 15, 2007
    Publication date: July 24, 2008
    Inventors: Ming Sound Tsao, Suzanne Lau, Paul Boutros, Melania Pintilie, Sandy Der, Frances A. Shepherd, Igor Jurisica, Linda Penn