Patents by Inventor Frances Ginn Howard

Frances Ginn Howard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SPECIMEN ENRICHMENT FOR OPTICAL TOMOGRAPHY CELL ANALYSIS
    Publication number: 20240068924
    Abstract: A method for enhancing gating performance of a cell sorter to prepare an enriched specimen for optical tomography cell analysis includes introducing a specimen into a FACS to generate 2D event data; generating a first scatterplot of the 2D data; identifying target objects; constructing a boundary within the first scatterplot to produce a first gate; counting target objects within the first gate; comparing the number of target objects within the first gate to a first predetermined value and adjusting the first gate as necessary. A boundary around a set of target objects is constructed in a second scatterplot to produce a subset second gate and target objects within the second gate are counted and the count compared to a second predetermined value. When a boundary around target objects meets specifications the first and second gates are stored in memory and used to enrich patient specimens.
    Type: Application
    Filed: August 29, 2022
    Publication date: February 29, 2024
    Inventors: Daniel J. Sussman, Timothy Bell, Frances Ginn Howard, Jonus Reyna
  • Specimen enrichment for optical tomography cell analysis
    Patent number: 11428692
    Abstract: A method for enhancing gating performance of a cell sorter to prepare an enriched specimen for optical tomography cell analysis includes introducing a specimen into a FACS to generate 2D event data; generating a first scatterplot of the 2D data; identifying target objects; constructing a boundary within the first scatterplot to produce a first gate; counting target objects within the first gate; comparing the number of target objects within the first gate to a first predetermined value and adjusting the first gate as necessary. A boundary around a set of target objects is constructed in a second scatterplot to produce a subset second gate and target objects within the second gate are counted and the count compared to a second predetermined value. When a boundary around target objects meets specifications the first and second gates are stored in memory and used to enrich patient specimens.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: August 30, 2022
    Inventors: Daniel J. Sussman, Timothy Bell, Frances Ginn Howard, Jonus Reyna
  • SPECIMEN ENRICHMENT FOR OPTICAL TOMOGRAPHY CELL ANALYSIS
    Publication number: 20200018704
    Abstract: A method for enhancing gating performance of a cell sorter to prepare an enriched specimen for optical tomography cell analysis includes introducing a specimen into a FACS to generate 2D event data; generating a first scatterplot of the 2D data; identifying target objects; constructing a boundary within the first scatterplot to produce a first gate; counting target objects within the first gate; comparing the number of target objects within the first gate to a first predetermined value and adjusting the first gate as necessary. A boundary around a set of target objects is constructed in a second scatterplot to produce a subset second gate and target objects within the second gate are counted and the count compared to a second predetermined value. When a boundary around target objects meets specifications the first and second gates are stored in memory and used to enrich patient specimens.
    Type: Application
    Filed: July 11, 2018
    Publication date: January 16, 2020
    Applicant: VISIONGATE, INC.
    Inventors: Daniel J. Sussman, Timothy Bell, Frances Ginn Howard, Jonus Reyna