Patents by Inventor Frances M. Gotch

Frances M. Gotch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HIV-1 core protein fragments
    Patent number: 5480967
    Abstract: The present invention provides peptidal fragments of human immunodeficiency virus (HIV) which interact specifically with a particular human leucocyte antigen (HLA) class I molecule to stimulate cytotoxic T lymphocyte immunity.
    Type: Grant
    Filed: July 6, 1992
    Date of Patent: January 2, 1996
    Assignee: United Biomedical, Inc.
    Inventors: Andre J. McMichael, Douglas F. Nixon, Alain R. M. Townsend, Frances M. Gotch
  • Assay for cytotoxic T cells
    Patent number: 5395751
    Abstract: A method of detecting in a sample CTL specific for a particular virus, e.g. HIV, comprises contacting the sample with a support carrying immobilized antibodies to a surface antigen on T cells; separating the support and attached materials; contacting the separated support with target cells matched to the HLA type of the source of the sample and with HLA matched peptide epitope of the virus that interacts with the CTL of interest; and monitoring lysis of the target cells.
    Type: Grant
    Filed: February 26, 1993
    Date of Patent: March 7, 1995
    Assignee: United Biomedical, Inc.
    Inventors: Andrew J. McMichael, Douglas F. Nixon, Frances M. Gotch