Patents by Inventor Frances Margaret Gotch

Frances Margaret Gotch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Plasmodium falciparum MHC class I-restricted CTL epitopes derived from pre-erythrocytic stage antigens
    Patent number: 5972351
    Abstract: A method of identifying peptides of an antigen of interest which are capable of recognition by or induction of cytotoxic T lymphocytes, comprises the steps of: ascertaining a "motif" of peptides which bind to a chosen HLA class I allele; providing peptides having this motif which are present in the known sequence of the antigen of interest; screening the peptides using an HLA assembly assay; and screening the resulting peptides for recognition by or induction of cytotoxic T lymphocytes. The above peptides have been identified by this method, and the peptides and vaccines containing them are also claimed.
    Type: Grant
    Filed: December 5, 1994
    Date of Patent: October 26, 1999
    Assignee: Isis Innovation Limited
    Inventors: Adrian Vivian Sinton Hill, Frances Margaret Gotch, John Elvin, Andrew James McMichael, Hilton Carter Whittle
  • HIV-1 core protein fragments
    Patent number: 5700469
    Abstract: The present invention provides peptidal fragments of human immunodeficiency virus (HIV) which interact specifically with a particular human leucocyte antigen (HLA) class I molecule to stimulate cytotoxic T lymphocyte immunity.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 23, 1997
    Assignee: Medical Research Council
    Inventors: Andre James McMichael, Douglas Fraser Nixon, Alain Robert Michael Townsend, Frances Margaret Gotch