Patents by Inventor Frances Platt

Frances Platt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF LYSOSOMAL DISORDERS (IL-1 ANTAGONISTS)
    Publication number: 20170190772
    Abstract: The invention relates to methods for treating a Lysosomal storage disease (LSD) in a patient. Kits for use in such methods are also provided.
    Type: Application
    Filed: July 8, 2015
    Publication date: July 6, 2017
    Applicant: OXFORD UNIVERSITY INNOVATION LIMITED
    Inventors: Frances PLATT, Nick PLATT, Raashid LUQMANI
  • TREATMENT OF LYSOSOMAL DISORDERS (ANTI-TNF THERAPY)
    Publication number: 20170165361
    Abstract: The invention relates to methods for treating a Lysosomal storage disease (LSD) in a patient. Kits for use in such methods are also provided.
    Type: Application
    Filed: July 8, 2015
    Publication date: June 15, 2017
    Inventors: Frances PLATT, Nick PLATT, Raashid LUQMANI
  • SUBSTRATE REDUCTION THERAPY
    Publication number: 20100204162
    Abstract: The present invention provides a compound which is an inhibitor of sphingolipid biosynthesis for use in the treatment of a disease which has a secondary Niemann-Pick type C disease like cellular phenotype.
    Type: Application
    Filed: June 26, 2008
    Publication date: August 12, 2010
    Inventors: Mary Frances Platt, Emyr Lloyd-Evans, Forbes Dennison Porter
  • Pharmaceutically active piperidine derivatives
    Publication number: 20060074107
    Abstract: Compounds of formula (I): wherein R represents various substituent groups, are useful as inhibitors of glucosylceramide synthase.
    Type: Application
    Filed: August 3, 2005
    Publication date: April 6, 2006
    Inventors: Terence Butters, Raymond Dwek, George Fleet, Michael Orchard, Frances Platt
  • Use of N-substituted imino sugars for appetite suppression
    Publication number: 20060025449
    Abstract: The present invention relates to compositions and methods for treating obesity. In particular, this invention describes the use of imino sugars, such as N-butyldeoxynojirimycin (NB-DNJ) for appetite suppression, thereby causing weight loss.
    Type: Application
    Filed: March 23, 2005
    Publication date: February 2, 2006
    Inventors: David Priestman, Aarnoud Spoel, Terry Butters, Raymond Dwek, Frances Platt
  • Therapeutic compositions and methods of treating glycolipid storage related disorders
    Publication number: 20050075305
    Abstract: A method for treating a glycolipid storage-related disorder, comprising administering a therapeutically effective amount of an inhibitor of glycolipid synthesis in combination with an agent capable of increasing the rate of glycolipid degradation or in combination with bone marrow transplantation. Inhibitors of glycolipid synthesis include N-butyldeoxynojirimycin (NB-DNJ), N-butyldeoxygalactonojirimycin (NB-DGJ) or N-nonyldeoxynojirimycin (NN-DNJ). Glycolipid storage-related disorders include Gaucher disease, Sandhoff's disease, Fabry's disease, Tay-Sach's disease, Niemann-Pick C storage disease, GM1 gangliosidosis, genetic disorders in which neuronal glycolipid accumulation contributes to disease pathology.
    Type: Application
    Filed: January 15, 2004
    Publication date: April 7, 2005
    Inventors: Raymond Dwek, Terence Butters, Mylvaganam Jeyakumar, Frances Platt, David Priestman
  • Inhibition of membrane-associated viral replication
    Patent number: 6465487
    Abstract: Methods for inhibiting morphogenesis of host cell membrane-budding viruses and infections caused thereby using compounds that inhibit host cell glucosidase or glucosyltransferase enzymes. Methods for treating lipid storage diseases using compounds that inhibit glucosyl transferance enzymes.
    Type: Grant
    Filed: December 10, 1998
    Date of Patent: October 15, 2002
    Assignees: Synergy Pharmaceuticals, Inc., Thomas Jefferson University, The Chancellor, Masters and Scholars of the University of Oxford
    Inventors: Timothy M. Block, Raymond A. Dwek, Baruch S. Blumberg, Anand Mehta, Frances Platt, Terry D. Butters, Nicole Zitzmann