Patents by Inventor Francesc Blasco

Francesc Blasco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-EGFR single-chain Fvs and anti-EGFR antibodies
    Patent number: 5844093
    Abstract: This invention relates to new anti-EGFR antibodies and single-chain Fvs (scFvs) thereof which can be obtained from phage-antibody libraries constructed from cells of an immunized mammalian, preferably a mouse. Two of the single-chain Fvs isolated from the phage-antibody libraries were engineered to create partially humanized whole antibody molecules. These chimeric anti-EGFR antibodies contain constant regions of human immunoglobulins, and can be used as well as the single-chain Fvs as agents for the diagnosis and therapy of human tumors.
    Type: Grant
    Filed: November 17, 1995
    Date of Patent: December 1, 1998
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: A. Cathrine Kettleborough, Mary M. Bendig, Keith H. Ansell, Detlef Gussow, Jaume Adan, Francesc Mitjans, Elisabet Rosell, Francesc Blasco, Jaume Piulats