Patents by Inventor Francesc Pla Rodas

Francesc Pla Rodas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 7135478
    Abstract: A compound of the formula wherein the substituents are defined as in the specification which compounds are useful in the treatment of cancer.
    Type: Grant
    Filed: August 31, 2004
    Date of Patent: November 14, 2006
    Assignee: Societe de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gérard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 7053102
    Abstract: Compositions for treating cancer comprising an amount of a camptothecin with a 7-ring ?-hydroxy lactone ring of the formula wherein the substituents are defined as in the specification sufficient to treat cancer.
    Type: Grant
    Filed: June 7, 2004
    Date of Patent: May 30, 2006
    Assignee: Societe de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • New analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Publication number: 20040254163
    Abstract: Compositions for treating cancer comprising an amount of a camptothecin with a 7-ring &bgr;-hydroxy lactone ring of the formula 1
    Type: Application
    Filed: June 7, 2004
    Publication date: December 16, 2004
    Applicant: SOCIETE DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 6815546
    Abstract: A compound of the formula wherein the substituents are defined as in the specification which compounds are useful in the treatment of cancer.
    Type: Grant
    Filed: February 6, 2002
    Date of Patent: November 9, 2004
    Assignee: Societe de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gérard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 6797715
    Abstract: A method of treating a cancer in warm-blooded animals by administration to the warm-blooded animals in need thereof a camptothecin analog a 7-ring member &bgr;-hydroxy lactone ring of the formula wherein the substituents are defined as in the specification.
    Type: Grant
    Filed: July 7, 2000
    Date of Patent: September 28, 2004
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 6762301
    Abstract: A process for the preparation of a compound of the formula wherein the substituents are defined as set forth in the specification comprising reacting a compound of the formula with a 2-halo-3-quinoline-methanol of the formula to obtain a compound of the formula which is then cyclized to form the compound of Formula I.
    Type: Grant
    Filed: January 30, 2002
    Date of Patent: July 13, 2004
    Assignee: Societe de Conseils de Recherches et Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • New analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Publication number: 20030004150
    Abstract: A compound of the formula 1
    Type: Application
    Filed: February 6, 2002
    Publication date: January 2, 2003
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • New analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Publication number: 20020160994
    Abstract: A process for the preparation of a compound of the formula 1
    Type: Application
    Filed: January 30, 2002
    Publication date: October 31, 2002
    Applicant: SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Comptothecin analogues, preparation methods therefor, use thereof as drugs, and pharmaceutical compositions containing said analogues
    Patent number: 6339091
    Abstract: The compound of the formula wherein the substituents are defined as in the specification and its non-toxic, pharmaceutically acceptable salts which are useful for the treatment of viral infections, parasitic diseases and the treatment of cancer.
    Type: Grant
    Filed: June 14, 1999
    Date of Patent: January 15, 2002
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Analogues of camptothecin, preparation procedures, their application as medicines and the pharmaceutical compositions comprising them
    Patent number: 6313135
    Abstract: A compound of the formula wherein the substituents are as defined in the specification and a method of inhibiting tumors.
    Type: Grant
    Filed: June 4, 1999
    Date of Patent: November 6, 2001
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri
  • Camptothecin analogues, preparation methods therefor, use thereof as drugs, and pharmaceutical compositions containing said analogues
    Patent number: 5981542
    Abstract: A camptothecin analog characterized in that the hydroxy lactone of the camptothecin is a .beta.-hydroxy lactone or the corresponding .beta.-hydroxyacid, resulting from the opening of said lactone, or a derivative of said .beta.-hydroxyacid, or a Pharmaceutically acceptable salt thereof, is disclosed. In particular, compounds of formulae (I) and (II) are disclosed. Methods for preparing the compounds of formulae (I) and (II), pharmaceutical compositions containing said containing said compounds, and their use, particularly as topoisomerase inhibitors and antitumoral drugs, are also disclosed.
    Type: Grant
    Filed: December 2, 1997
    Date of Patent: November 9, 1999
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri
  • Benzofuranylimidazole derivatives and therapeutical compositions containing the same
    Patent number: 5354769
    Abstract: The invention relates to benzofuranylimidazole derivatives of the general formula (1) ##STR1## wherein R.sub.1 and R.sub.2 represent various radicals, to a process for their preparation and to pharmaceutical compositions containing them.
    Type: Grant
    Filed: December 2, 1993
    Date of Patent: October 11, 1994
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Jesus A. Garcia Sevilla, Jose J. Meana Martinez, Fernando Barturen Fernandez, Fernando A. Geijo Caballero, Angel Menargues Banos, Rosendo Obach Vidal, Francesc Pla Rodas