Patents by Inventor Francesca BELARDINILLI

Francesca BELARDINILLI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STABLE SYSTEM FOR THE IN VITRO CULTURE OF CEREBELLAR GRANULE CELL PRECURSORS (GCP), STABLE METHOD FOR THE IN VITRO CULTURE OF SAID CELLS AND USE OF SAID SYSTEM OR METHOD FOR IN VITRO CULTURE
    Publication number: 20220177834
    Abstract: This invention relates to an in vitro system for the culture of cerebellar granule cell precursors (granule cell progenitors, GCP) comprising a culture support, mammalian GCP cells and a culture medium comprising at least SAG (Smoothened agonist) and EGF (Epidermal Growth Factor), and a method for the in vitro culture of GCP cells, use of the above-mentioned culture system or method of culture for the generation of in vitro models for study of the pathophysiology of cerebellar granules or use of the above-mentioned culture system or method of culture for use in gene therapy and cell therapy approaches to cerebellar diseases caused by damage or neurodegeneration.
    Type: Application
    Filed: March 19, 2020
    Publication date: June 9, 2022
    Inventors: Giuseppe GIANNINI, Valeria COLICCHIA, Carlo CAPALBO, Francesca FABRETTI, Stefano DI GIULIO, Francesca BELARDINILLI, MariaLaura PETRONI, Maria Sahùn RONCERO