Patents by Inventor Francesca Buffa

Francesca Buffa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HYPOXIA TUMOUR MARKERS
    Publication number: 20120329662
    Abstract: The present invention relates to a method for assessing a hypoxia phenotype of a tumour of a subject in which the gene expression of between 3 and 50 hypoxia-related genes of a sample obtained from said tumour of the subject is determined, thereby obtaining a sample expression profile of said hypoxia-related genes. The sample gene expression profile is then compared with a reference expression profile of said hypoxia-related genes. The hypoxia-related genes comprise at least SLC2A1, VEGFA and PGAM1. Probes, arrays and kits for use in the method are also disclosed.
    Type: Application
    Filed: December 22, 2010
    Publication date: December 27, 2012
    Inventors: Catharine West, Crispin Miller, Adrian Harris, Francesca Buffa
  • Knowledge-Based Proliferation Signatures and Methods of Use
    Publication number: 20110059074
    Abstract: The present invention provides methods and compositions for predicting patient responses to cancer treatment using a proliferation gene signature. These methods can comprise measuring in a biological sample from a patient the levels of gene expression of a group of the genes designated herein. The present invention also provides for microarrays that can detect expression from a group of genes.
    Type: Application
    Filed: May 2, 2008
    Publication date: March 10, 2011
    Inventors: Maud H.W. Starmans, Balaji Krishnapuram, Ranand G. Seigneuric, Harald Steck, Dimitry S.A. Nuyten, Francesca Buffa, Adrian Lewellyn Harris, Bradly G. Wouters, Philippe Lambin, R. Bharat Rao, Sriram Krishnan