Patents by Inventor Francesca Ceccacci

Francesca Ceccacci has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 17-alpha-substituted derivatives of estradiol with wound-healing activity
    Patent number: 8357675
    Abstract: The invention relates to 17?-(5-hydroxy-C5-hydrocarbyl)-1,3,5(10)-estratrien-3,17?-diol derivatives having cicatrising activity, preferably for topical use on wounds, without significant systemic effects, and to pharmaceutical compositions containing them. In particular, the invention relates to estradiol 17?-(5-hydroxypentyn-1-yl)derivatives and 3-esters, 5?-esters and 3,5?-diesters thereof and to a process for the preparation thereof by reaction of 3-OR-protected estrone with an alkali metal derivative of OR-protected 5-pentynol, followed by 3-, 5-? or 3,5?-esterifÊcation.
    Type: Grant
    Filed: July 28, 2006
    Date of Patent: January 22, 2013
    Assignee: Euticals S.p.A.
    Inventors: Gillian Ashcroft, Mario Brufani, Francesca Ceccacci, Paolo Maria Farina, Luigi Filocamo, Barbara Garofalo, Roberta Joudioux, Adriana Maggi, Rinaldo Marini Bettolo, Luisa Maria Migneco
  • 17-ALPHA-SUBSTITUTED DERIVATIVES OF ESTRADIOL WITH WOUND-HEALING ACTIVITY
    Publication number: 20100035796
    Abstract: The invention relates to 17?-(5-hydroxy-C5-hydrocarbyl)-1,3,5(10)-estratrien-3,17?-diol derivatives having cicatrising activity, preferably for topical use on wounds, without significant systemic effects, and to pharmaceutical compositions containing them. In particular, the invention relates to estradiol 17?-(5-hydroxypentyn-1-yl)derivatives and 3-esters, 5?-esters and 3,5?-diesters thereof and to a process for the preparation thereof by reaction of 3-OR-protected estrone with an alkali metal derivative of OR-protected 5-pentynol, followed by 3-, 5-? or 3,5?-esterification.
    Type: Application
    Filed: July 28, 2006
    Publication date: February 11, 2010
    Applicant: EUTICALS S.P.A.
    Inventors: Gillian Ashcroft, Mario Brufani, Francesca Ceccacci, Paolo Maria Farina, Luigi Filocamo, Barbara Garofalo, Roberta Joudioux, Adriana Maggi, Rinaldo Marini Bettolo, Luisa Maria Migneco