Patents by Inventor Francesca Cottini

Francesca Cottini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STK4 inhibitors for treatment of hematologic malignancies
    Patent number: 10710978
    Abstract: The application relates to compounds of Formula (I?): which modulate the activity of a kinase (e.g., STK4), a pharmaceutical composition comprising the compound, and a method of treating or preventing a disease or disorder associated with the modulation of a kinase, such as STK4.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: July 14, 2020
    Assignees: DANA-FARBER CANCER INSTITUTE, INC., FONDAZIONE CENTRO SAN RAFFAELE
    Inventors: Nathanael S. Gray, Sara Buhrlage, Kenneth Anderson, Francesca Cottini, Giovanni Tonon
  • Compositions and methods for treating multiple myeloma
    Patent number: 10302644
    Abstract: The invention provides, inter alia, methods of prognosing the survival of a multiple myeloma patient based levels of TP53RK in multiple myeloma cells of the patient. Also provided are methods of screening for therapeutic agents for treating multiple myeloma based on their ability to decrease TP53RK levels or activity in a patient with multiple myeloma.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: May 28, 2019
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Teru Hideshima, Kenneth C. Anderson, Francesca Cottini
  • Targets in multiple myeloma and other disorders
    Patent number: 10017767
    Abstract: An agent that increases YAP1 levels for use in the treatment of hematopoietic disorders.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: July 10, 2018
    Assignees: FONDAZIONE CENTRO SAN RAFFAELE, DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Giovanni Tonon, Francesca Cottini, Kenneth Carl Anderson
  • STK4 INHIBITORS FOR TREATMENT OF HEMATOLOGIC MALIGNANCIES
    Publication number: 20180111916
    Abstract: The application relates to compounds of Formula (I?): which modulate the activity of a kinase (e.g., STK4), a pharmaceutical composition comprising the compound, and a method of treating or preventing a disease or disorder associated with the modulation of a kinase, such as STK4.
    Type: Application
    Filed: March 31, 2016
    Publication date: April 26, 2018
    Inventors: Nathanael S. GRAY, Sara BUHRLAGE, Kenneth ANDERSON, Francesca COTTINI, Giovanni TONON
  • COMPOSITIONS AND METHODS FOR TREATING MULTIPLE MYELOMA
    Publication number: 20170356917
    Abstract: The invention provides, inter alia, methods of prognosing the survival of a multiple myeloma patient based levels of TP53RK in multiple myeloma cells of the patient. Also provided are methods of screening for therapeutic agents for treating multiple myeloma based on their ability to decrease TP53RK levels or activity in a patient with multiple myeloma.
    Type: Application
    Filed: October 20, 2015
    Publication date: December 14, 2017
    Inventors: Teru Hideshima, Kenneth C. Anderson, Francesca Cottini
  • NOVEL TARGETS IN MULTIPLE MYELOMA AND OTHER DISORDERS
    Publication number: 20150252368
    Abstract: An agent that increases YAP1 levels for use in the treatment of hematopoietic disorders.
    Type: Application
    Filed: November 5, 2013
    Publication date: September 10, 2015
    Inventors: Giovanni Tonon, Francesca Cottini, Kenneth Carl Anderson