Patents by Inventor Francesca DE FRANCO

Francesca DE FRANCO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRIMIDINONE COMPOUNDS FOR TREATING ACUTE INFLAMMATION
    Publication number: 20230414615
    Abstract: The present disclosure relates to a method of treating an acute inflammatory condition in a subject comprising administering to the subject a therapeutically effective amount of a pyrimidinone compound.
    Type: Application
    Filed: May 24, 2023
    Publication date: December 28, 2023
    Inventors: Roberto PELLICCIARI, Nicola GIACCHÈ, Francesca DE FRANCO
  • INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE
    Publication number: 20230381177
    Abstract: The present disclosure discloses compounds capable of modulating the activity of ?-amino-?-carboxymuconic acid semialdehyde decarboxylase (ACMSD), which are useful for the prevention and/or the treatment of diseases and disorders associated with defects in NAD+ biosynthesis, e.g., metabolic disorders, neurodegenerative diseases, chronic inflammatory diseases, kidney diseases, and diseases associated with ageing. The present application also discloses pharmaceutical compositions comprising said compounds and the use of such compounds as a medicament.
    Type: Application
    Filed: August 9, 2023
    Publication date: November 30, 2023
    Inventors: Roberto PELLICCIARI, Paride LISCIO, Nicola GIACCHE, Francesca DE FRANCO
  • COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF TUMORS
    Publication number: 20230052747
    Abstract: The present invention relates to compounds of Formula (Ia) or pharmaceutically acceptable salts, hydrates, solvates, clathrates, polymorphs, stereoisomers thereof. It further discloses a pharmaceutical composition comprising compounds of Formula (Ia) and the use of compounds of Formula (Ib), in particular for the use in the treatment of diseases or disorders wherein disrupting Rad51-BRCA2 interaction is beneficial.
    Type: Application
    Filed: December 11, 2020
    Publication date: February 16, 2023
    Inventors: Andrea Cavalli, Domenico Milano, Marcella Manerba, Greta Bagnolini, Jose Antonio Ortega Martinez, Marinella Roberti, Giuseppina Di Stefano, Roberto Pellicciari, Francesca De Franco, Saverio Minucci, Pier Giuseppe Pelicci, Viola Previtali
  • INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE
    Publication number: 20220354848
    Abstract: The present disclosure discloses compounds capable of modulating the activity of ?-amino-?-carboxymuconic acid semialdehyde decarboxylase (ACMSD), which are useful for the prevention and/or the treatment of diseases and disorders associated with defects in NAD+ biosynthesis, e.g., metabolic disorders, neurodegenerative diseases, chronic inflammatory diseases, kidney diseases, and diseases associated with ageing. The present application also discloses pharmaceutical compositions comprising said compounds and the use of such compounds as a medicament.
    Type: Application
    Filed: May 19, 2021
    Publication date: November 10, 2022
    Inventors: Roberto PELLICCIARI, Paride LISCIO, Nicola GIACCHE, Francesca DE FRANCO
  • INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE
    Publication number: 20210379069
    Abstract: The present disclosure discloses compounds capable of modulating the activity of ?-amino-?-carboxymuconic acid semialdehyde decarboxylase (ACMSD), which are useful for the prevention and/or the treatment of diseases and disorders associated with defects in NAD+ biosynthesis, e.g., metabolic disorders, neurodegenerative diseases, chronic inflammatory diseases, kidney diseases, and diseases associated with ageing. The present application also discloses pharmaceutical compositions comprising said compounds and the use of such compounds as a medicament.
    Type: Application
    Filed: May 19, 2021
    Publication date: December 9, 2021
    Inventors: Roberto PELLICCIARI, Paride LISCIO, Nicola GIACCHE, Francesca DE FRANCO