Patents by Inventor Francesca Re

Francesca Re has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LIPOSOMES AND USES THEREOF
    Publication number: 20220313607
    Abstract: The present invention relates to a liposome containing a lipid or lipid mixture, phosphatidic acid and/or cardiolipin and apolipoprotein E for use in the treatment and/or prevention of amyloidosis, wherein the amyloidosis is not Alzheimer's disease and pharmaceutical compositions containing the same.
    Type: Application
    Filed: July 31, 2020
    Publication date: October 6, 2022
    Applicant: UNIVERSITÀ DEGLI STUDI DI MILANO - BICOCCA
    Inventors: Francesca RE, Massimo Ernesto MASSERINI, Marco Antonio Ercole SARDINA
  • Liposomes active in-vivo on neurodegenerative diseases
    Patent number: 10010505
    Abstract: New liposomes are described, comprising: (i) phosphatidic acid and/or cardiolipin; (ii) apolipoprotein E (ApoE) or derivatives thereof. The so modified liposomes, administered systemically, obtain a dramatic in-vivo reduction of the amyloid plaque in the central nervous system, allowing an effective treatment of neurodegenerative diseases, in particular Alzheimer's disease.
    Type: Grant
    Filed: October 2, 2014
    Date of Patent: July 3, 2018
    Assignee: UNIVERSITA DEGLI STUDI DI MILANO-BICOCCA
    Inventors: Massimo Masserini, Francesca Re, Giulio Sancini, Gianluigi Forloni, Mario Salmona
  • Liposomes capable of effectively binding the beta amyloid peptide
    Patent number: 9427405
    Abstract: Novel liposomes are described which are capable of effectively binding beta amyloid peptide and are useful for the treatment, prevention and diagnosis of Alzheimer's disease. Binding ability is provided by the presence in the formulation of particular natural lipids identified by the Applicant. These comprise a constant component, made up of cholesterol and sphingomyelin, and an additional variable component, made up of selected lipids.
    Type: Grant
    Filed: June 10, 2009
    Date of Patent: August 30, 2016
    Assignee: Universita degli Studi de Milano-Bicocca
    Inventors: Massimo Masserini, Francesca Re, Maria Silvia Sesana
  • LIPOSOMES ACTIVE IN-VIVO ON NEURODEGENERATIVE DISEASES
    Publication number: 20150017235
    Abstract: New liposomes are described, comprising: (i) phosphatidic acid and/or cardiolipin; (ii) apolipoprotein E (ApoE) or derivatives thereof. The so modified liposomes, administered systemically, obtain a dramatic in-vivo reduction of the amyloid plaque in the central nervous system, allowing an effective treatment of neurodegenerative diseases, in particular Alzheimer's disease.
    Type: Application
    Filed: October 2, 2014
    Publication date: January 15, 2015
    Inventors: Massimo MASSERINI, Francesca RE, Giulio SANCINI, Gianluigi FORLONI, Mario SALMONA
  • Liposomes active in-vivo on neurodegenerative diseases
    Patent number: 8877236
    Abstract: New liposomes are described, comprising: (i) phosphatidic acid and/or cardiolipin; (ii) apolipoprotein E (ApoE) or derivatives thereof. The so modified liposomes, administered systemically, obtain a dramatic in-vivo reduction of the amyloid plaque in the central nervous system, allowing an effective treatment of neurodegenerative diseases, in particular Alzheimer's disease.
    Type: Grant
    Filed: June 28, 2012
    Date of Patent: November 4, 2014
    Assignee: Universita Degli Studi di Milano-Bicocca
    Inventors: Massimo Masserini, Francesca Re, Giulio Sancini, Gianluigi Forloni, Mario Salmona
  • LIPOSOMES ACTIVE IN-VIVO ON NEURODEGENERATIVE DISEASES
    Publication number: 20140004172
    Abstract: New liposomes are described, comprising: (i) phosphatidic acid and/or cardiolipin; (ii) apolipoprotein E (ApoE) or derivatives thereof. The so modified liposomes, administered systemically, obtain a dramatic in-vivo reduction of the amyloid plaque in the central nervous system, allowing an effective treatment of neurodegenerative diseases, in particular Alzheimer's disease.
    Type: Application
    Filed: June 28, 2012
    Publication date: January 2, 2014
    Inventors: Massimo MASSERINI, Francesca RE, Giulio SANCINI, Gianluigi FORLONI, Mario SALMONA
  • Liposomes Capable of Effectively Binding the Beta Amyloid Peptide
    Publication number: 20110177158
    Abstract: Novel liposomes are described which are capable of effectively binding beta amyloid peptide and are useful for the treatment, prevention and diagnosis of Alzheimer's disease. Binding ability is provided by the presence in the formulation of particular natural lipids identified by the Applicant. These comprise a constant component, made up of cholesterol and sphingomyelin, and an additional variable component, made up of selected lipids.
    Type: Application
    Filed: June 10, 2009
    Publication date: July 21, 2011
    Applicant: Universita degli Studi di Milano-Bicocca
    Inventors: Massimo Masserini, Francesca Re, Maria Silvia Sesana