Patents by Inventor Francesco Ciardella

Francesco Ciardella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of ziprasidone
    Patent number: 7608711
    Abstract: A process for the preparation of ziprasidone and a novel intermediate useful in its preparation. The process comprises the reduction of a compound (III) to give a compound (V) which is then reduced to compound (II). This is reacted with compound (IV) to give the desired compound.
    Type: Grant
    Filed: November 13, 2006
    Date of Patent: October 27, 2009
    Assignee: Dipharma Francis Srl
    Inventors: Jacopo Zanon, Oscar Martini, Francesco Ciardella, Luca Gregori, Federico Sbrogio, Andrea Castellin
  • METHOD FOR MANUFACTURE OF SERTINDOLE
    Publication number: 20090264656
    Abstract: The present invention relates to a novel method for manufacture of sertindole comprising manufacturing 5-chloro-1-(4-fluorophenyl)-indole and converting it to sertindole wherein the method for manufacture of 5-chloro-1-(4-fluorophenyl)-indole comprises reacting 5-chloro-indole with a 4-fluorophenylhalide in the presence of a base, a chelating ligand and catalytic amounts or a copper salt comprising copper(I) or copper(II) and an anion which does not interfere in an unfavourable way with the reaction.
    Type: Application
    Filed: January 27, 2009
    Publication date: October 22, 2009
    Applicant: H. LUNDBECK A/S
    Inventors: Jacopo Zanon, Marco Villa, Francesco Ciardella
  • Process for synthesis of 4-4?-diamino-diphenyl-sulfone
    Patent number: 7531694
    Abstract: A new process for the preparation and purification of 4-4?-diamino-diphenyl-sulfone (dapsone) is described. The process described is a three step process comprising a condensation reaction with the synthesis of a thioether intermediate and then steps of oxidation and reduction in suitable conditions in order to obtain a product with good yield and purity.
    Type: Grant
    Filed: July 7, 2004
    Date of Patent: May 12, 2009
    Assignee: Lundbeck Pharmaceuticals Italy, S.p.A.
    Inventors: Marco Villa, Carla De Faveri, Riccardo Zanotti, Francesco Ciardella, Fabrizio Borin
  • Process for Synthesis of 4-4'-Diamino-Diphenyl-Sulfone
    Publication number: 20080293970
    Abstract: A new process for the preparation and purification of 4-4?-diamino-diphenyl-sulfone (dapsone) is described. The process described is a three step process comprising a condensation reaction with the synthesis of a thioeter intermediate and then steps of oxidation and reduction in suitable conditions in order to obtain a product with good yield and purity.
    Type: Application
    Filed: July 7, 2004
    Publication date: November 27, 2008
    Inventors: Marco Villa, Carla De Faveri, Riccardo Zanotti, Francesco Ciardella, Fabrizio Borin
  • Process for the preparation of ziprasidone
    Publication number: 20070117810
    Abstract: A process for the preparation of ziprasidone and a novel intermediate useful in its preparation. The process comprises the reduction of a compound (III) to give a compound (V) which is then reduced to compound (II). This is reacted with compound (IV) to give the desired compound.
    Type: Application
    Filed: November 13, 2006
    Publication date: May 24, 2007
    Applicants: DIPHARMA S. P. A., LUNDBECK PHARMACEUTICALS ITALY S. P. A.
    Inventors: Jacopo Zanon, Oscar Martini, Francesco Ciardella, Luca Gregori, Federico Sbrogio, Andrea Castellin