Patents by Inventor Francesco Cirillo

Francesco Cirillo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cytokine inhibitors
    Patent number: 7078419
    Abstract: Disclosed are compounds of formula (I) Where Ar1, X, Y, Q, W, R3, R4, R5, R6 and Ry are defined herein. The compounds of the invention inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. The compounds are also useful for treating diseases or conditions related to oncology and anticoagulant or fibrinolytic therapy. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.
    Type: Grant
    Filed: February 27, 2004
    Date of Patent: July 18, 2006
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier Francesco Cirillo, Donghong Amy Gao, Daniel R. Goldberg, Abdelhakim Hammach, Ming-Hong Hao, Victor Marc Kamhi, Neil Moss, Matthew Russell Netherton, Kevin Chungeng Qian, Mark Stephen Ralph, Lifen Wu, Zhaoming Xiong, Ronald A. Aungst, Jr.
  • 1,4-benzofused urea compounds useful in treating cytokine mediated diseases
    Patent number: 7041669
    Abstract: Disclosed are 1,4-disubstituted benzo-fused urea compounds of formula (I): wherein Ar, X, A, L, and Q of formula(I) are defined herein. The compounds inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.
    Type: Grant
    Filed: February 19, 2003
    Date of Patent: May 9, 2006
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier Francesco Cirillo, Abdelhakim Hammach, John Robinson Regan
  • Fluorinated di-aryl urea compounds
    Patent number: 6872726
    Abstract: Disclosed are compounds of formula (I): wherein R1, R2, W and X of formula (I) are defined herein. The compounds inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.
    Type: Grant
    Filed: August 1, 2003
    Date of Patent: March 29, 2005
    Assignee: Boehringer Ingelheim Pharmaceuticals Inc.
    Inventors: Pier Francesco Cirillo, Abdelhakim Hammach, Victor Kamhi, Neil Moss, Paul S. Riska, Christopher Pargellis
  • Compounds useful as anti-inflammatory agents
    Patent number: 6852717
    Abstract: Disclosed are compounds useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of making such compounds.
    Type: Grant
    Filed: May 10, 2002
    Date of Patent: February 8, 2005
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier Francesco Cirillo, Daniel R. Goldberg, Abdelhakim Hammach, Neil Moss, John Robinson Regan
  • 1,4-Disubstituted benzo-fused urea compounds
    Patent number: 6825184
    Abstract: Disclosed are compounds of the formulas (I) & (II) shown below which are active as anti-inflammatory agents. Also disclosed are methods of using and making such compounds. wherein G, X, A and Q are described herein.
    Type: Grant
    Filed: October 11, 2002
    Date of Patent: November 30, 2004
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier Francesco Cirillo, Abdelhakim Hammach, John R. Regan
  • Cytokine inhibitors
    Publication number: 20040186114
    Abstract: Disclosed are compounds of formula (I) 1
    Type: Application
    Filed: February 27, 2004
    Publication date: September 23, 2004
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier Francesco Cirillo, Donghong Amy Gao, Daniel R. Goldberg, Abdelhakim Hammach, Ming-Hong Hao, Victor Marc Kamhi, Neil Moss, Matthew Russell Netherton, Kevin Chungeng Qian, Mark Stephen Ralph, Lifen Wu, Zhaoming Xiong
  • Carbamate and oxamide compounds
    Patent number: 6743788
    Abstract: Disclosed are novel aromatic compounds of the formula(I) described herein, wherein G, E, W, Ar, X, Y and Z are disclosed herein. The compounds are useful for treating cytokine mediated diseases or conditions such as chronic inflammatory diseases. Also disclosed are pharmaceutical compositions containing and processes of making such compounds.
    Type: Grant
    Filed: May 17, 2002
    Date of Patent: June 1, 2004
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier Francesco Cirillo, Victor Kamhi, John Robinson Regan, Michele Tsang
  • Fluorinated di-aryl urea compounds
    Publication number: 20040077647
    Abstract: Disclosed are compounds of formula (I): 1
    Type: Application
    Filed: August 1, 2003
    Publication date: April 22, 2004
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier Francesco Cirillo, Abdelhakim Hammach, Victor Kamhi, Neil Moss, Paul S. Riska, Christopher Pargellis
  • 1,4-disubstituted benzo-fused cycloalkyl urea compounds
    Patent number: 6720321
    Abstract: Disclosed are compounds of the formula (I) shown below which are active as anti-inflammatory agents. Also disclosed are methods of using and making such compounds. wherein n, X, A, L, J, p, Q, Y and z are described herein.
    Type: Grant
    Filed: May 24, 2002
    Date of Patent: April 13, 2004
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier Francesco Cirillo, Eugene R. Hickey
  • 1,4-Benzofused urea compounds useful in treating cytokine mediated diseases
    Publication number: 20030232865
    Abstract: Disclosed are 1,4-disubstituted benzo-fused urea compounds of formula (I): 1
    Type: Application
    Filed: February 19, 2003
    Publication date: December 18, 2003
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier Francesco Cirillo, Abdelhakim Hammach, John Robinson Regan
  • 1,4-Disubstituted benzo-fused urea compounds
    Publication number: 20030162968
    Abstract: Disclosed are compounds of the formulas (I) & (II) shown below which are active as anti-inflammatory agents. Also disclosed are methods of using and making such compounds.
    Type: Application
    Filed: October 11, 2002
    Publication date: August 28, 2003
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier Francesco Cirillo, Abdelhakim Hammach, John R. Regan
  • 1,4-disubstituted benzo-fused cycloalkyl urea compounds
    Publication number: 20030100608
    Abstract: Disclosed are compounds of the formula (I) shown below which are active as anti-inflammatory agents. Also disclosed are methods of using and making such compounds.
    Type: Application
    Filed: May 24, 2002
    Publication date: May 29, 2003
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier Francesco Cirillo, Eugene R. Hickey
  • Novel carbamate and oxamide compounds
    Publication number: 20030092702
    Abstract: Disclosed are novel aromatic compounds of the formula(I) described herein, wherein G, E, W, Ar, X, Y and Z are disclosed herein. The compounds are useful for treating cytokine mediated diseases or conditions such as chronic inflammatory diseases. Also disclosed are pharmaceutical compositions containing and processes of making such compounds.
    Type: Application
    Filed: May 17, 2002
    Publication date: May 15, 2003
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier Francesco Cirillo, Victor Kamhi, John Robinson Regan, Michele Tsang
  • 1,4-Disubstituted benzo-fused compounds
    Publication number: 20030083333
    Abstract: Disclosed are novel 1,4-disubstituted benzo-fused compounds wherein G, X, L, Q, n and Y are defined herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of making such compounds.
    Type: Application
    Filed: April 10, 2002
    Publication date: May 1, 2003
    Inventors: Pier Francesco Cirillo, Daniel R. Goldberg, Abdelhakim Hammach, Neil Moss, Kristen Mueller, John Robinson Regan
  • Aromatic heterocyclic compounds as antiinflammatory agents
    Patent number: 6525046
    Abstract: Disclosed are novel aromatic heterocyclic compounds of the formula(I) wherein Ar1,Ar2,L,Q and X are described herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of making such compounds.
    Type: Grant
    Filed: June 7, 2002
    Date of Patent: February 25, 2003
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier Francesco Cirillo, Roger Dinallo, John Robinson Regan, Paul S. Riska, Alan David Swinamer, Zhulin Tan, Brian Andrew Walter
  • Compounds useful as anti-inflammatory agents
    Publication number: 20030008868
    Abstract: Disclosed are compounds useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of making such compounds.
    Type: Application
    Filed: May 10, 2002
    Publication date: January 9, 2003
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier Francesco Cirillo, Daniel R. Goldberg, Abdelhakim Hammach, Neil Moss, John Robinson Regan
  • Mobile apparatus for the purification of polluted air, and process therefor
    Patent number: 5676913
    Abstract: A vehicle, preferably a public transport vehicle, transports an apparatus providing for intake of polluted air, which is purified of carbon, nitrogen and sulphur oxides, unburned matter and particulate, the impurities being collected and disposed of after a working cycle of around 10 hours. The energy consumption is negligible when compared with the volume of air treated. (FIG. 2).
    Type: Grant
    Filed: July 7, 1995
    Date of Patent: October 14, 1997
    Assignee: BCP S.r.l.
    Inventors: Francesco Cirillo, Remo Pimpinelli