Patents by Inventor Francesco Facchiano

Francesco Facchiano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD TO PERFORM DIAGNOSIS AND PROGNOSIS OF MELANOMA AND KIT
    Publication number: 20210102947
    Abstract: The present invention refers to a method to perform a diagnosis of melanoma in a subject, as well as a method to perform a prognosis of a subject suffering from melanoma. Moreover, the present invention refers to a kit which allows to perform a non-invasive diagnosis of melanoma in a subject, and/or to perform a prognosis of a subject suffering from melanoma.
    Type: Application
    Filed: April 16, 2019
    Publication date: April 8, 2021
    Inventors: Francesco FACCHIANO, Antonio FACCHIANO, Daniela Agnese D'ARCANGELO
  • Peptide inhibiting platelet derived growth factor (PDGF-BB) and fibroblast growth factor (bFGF) activity
    Patent number: 7009036
    Abstract: A novel peptide, derived from the human fibroblast growth factor (bFGF), is identified. The molecule is able to inhibit in vitro the effects of Platelet Derived Growth Factor (PDGF-BB) and basic Fibroblast Growth Factor (bFGF) on primary rat smooth muscle cells (RASMC) and primary bovine endothelial cells (BAEC) The molecule is also able to inhibit in vivo angiogenesis CD1 mice.
    Type: Grant
    Filed: February 20, 2002
    Date of Patent: March 7, 2006
    Assignee: Provincia Italiana Della Congregazione Dei Figli Dell'Immacolata Concezione—Instituto Dermopatico Dell'Immacolata
    Inventors: Antonio Facchiano, Francesco Facchiano, Angelo Facchiano
  • Peptide inhibiting platelet derived growth factor (PDGF-BB) and fibroblast growth factor (bFGF) activity
    Publication number: 20060014693
    Abstract: A novel peptide, derived from the human fibroblast growth factor (bFGF), is identified. Said molecule is able to inhibit in vitro the effects of Platelet Derived Growth Factor (PDGF-BB) and basic Fibroblast Growth Factor (bFGF) on primary rat smooth muscle cells (RASMC) and primary bovine endothelial cells (BAEC). Said molecule is also able to inhibit in vivo angiogenesis CD1 mice.
    Type: Application
    Filed: June 29, 2005
    Publication date: January 19, 2006
    Applicants: DELL' IMMACOLATA CONCEZIONE-ISTITUTO DERMOOPATICO DELL' IMMACOLATA
    Inventors: Antonio Facchiano, Francesco Facchiano, Angelo Facchiano
  • RGD-analog non-peptidic molecules having anti-adhesive, anti-migration and anti-proliferative effects
    Patent number: 6627769
    Abstract: Novel molecules without intramolecular peptidic bonds, able to mimic the RGD peptide, containing ARG-GLY-ASP motif “arginine-glycine-aspartic acid” (that is a potent inhibitor, in vivo and in vitro, of cellular adhesion) In vitro experimentation demonstrated that said molecules are efficient inhibitors of RASMC adhesion, proliferation and migration.
    Type: Grant
    Filed: February 20, 2002
    Date of Patent: September 30, 2003
    Assignee: Provincia Italiana Della Congregzaione dei Figli Dell'Immacolata Concezione - Istituto Dermopatico Dell'Immacolata
    Inventors: Antonio Facchiano, Francesco Facchiano, Ivan Rossi, Rita Casadio
  • Peptide inhibiting platelet derived growth factor (PDGF-BB) and fibroblast growth factor (bFGF) activity
    Publication number: 20020119931
    Abstract: A novel peptide, derived from the human fibroblast growth factor (bFGF), is identified. The molecule is able to inhibit in vitro the effects of Platelet Derived Growth Factor (PDGF-BB) and basic Fibroblast Growth Factor (bFGF) on primary rat smooth muscle cells (RASMC) and primary bovine endothelial cells (BAEC) The molecule is also able to inhibit in vivo angiogenesis CD1 mice.
    Type: Application
    Filed: February 20, 2002
    Publication date: August 29, 2002
    Inventors: Antonio Facchiano, Francesco Facchiano, Angelo Facchiano
  • RGD-analog non-peptidic molecules having anti-adhesive, anti-migration and anti-proliferative effects
    Publication number: 20020119932
    Abstract: Novel molecules without intramolecular peptidic bonds, able to mimic the RGD peptide, containing ARG-GLY-ASP motif “arginine-glycine-aspartic acid” (that is a potent inhibitor, in vivo and in vitro, of cellular adhesion) In vitro experimentation demonstrated that said molecules are efficient inhibitors of RASMC adhesion, proliferation and migration.
    Type: Application
    Filed: February 20, 2002
    Publication date: August 29, 2002
    Inventors: Antonio Facchiano, Francesco Facchiano, Ivan Rossi, Rita Casadio