Patents by Inventor Francesco Paolini
Francesco Paolini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8684959Abstract: An extracorporeal blood treatment apparatus comprises a sensor (10) for emitting a signal indicating a change of hematic volume of an individual (7) subjected to a treatment and a weight loss system for actuating the individual's weight loss. A control unit (20) receives an effective weight value of the individual and a desired weight loss value and from these values determines a desired value of a change in hematic volume at end of treatment. The weight loss system is controlled on a basis of the hematic volume change signal and the desired value of the hematic volume change. The apparatus enables automatic control of a dialysis operation while preventing some complications arising from hypotension.Type: GrantFiled: July 3, 2009Date of Patent: April 1, 2014Assignee: Gambro Lundia ABInventors: Francesco Paolini, Francesco Fontanazzi, Fabio Grandi
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Publication number: 20140088483Abstract: An apparatus for extracorporeal blood treatment is described, including a treatment unit, an extracorporeal blood circuit, an infusion line of a replacement fluid, a dialysis line connected in inlet to the second chamber, and a fluid evacuation line; sensors for determining a first parameter relating to a patient's blood volume (BV %) a second parameter relating to an ultrafiltration flow rate (UFR) or to a patient's weight loss rate (WLR), a third parameter (Cd, Na) relating to a conductivity or concentration of a liquid crossing the dialysis line and/or the infusion line, and a fourth parameter relating to an infusion flow rate (QINF), and a control unit for performing a control procedure.Type: ApplicationFiled: March 20, 2012Publication date: March 27, 2014Applicant: GAMBRO LUNDIA ABInventors: Francesco Fontanazzi, Alessandro Surace, Francesco Paolini
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Publication number: 20140074008Abstract: An apparatus for extracorporeal blood treatment including a treatment unit; an extracorporeal blood circuit; an infusion line of a replacement fluid; a dialysis line connected in inlet to the second chamber; a fluid evacuation line; sensors for determining a first parameter relating to a patient's blood volume (BV %), a second parameter relating to an ultrafiltration flow rate (UFR) or to a patient's weight loss rate (WLR), a third parameter (Cd, Na) relating to a conductivity or concentration of a liquid crossing the dialysis line and/or the infusion line, and a fourth parameter relating to an infusion flow rate (QINF), and a control unit performing a control procedure to determine a variation in blood volume (BV %) and perform a setting sequence, wherein the control unit regulates a transmembrane pressure (TMP) to values which enable maximising the convective exchanges.Type: ApplicationFiled: March 20, 2012Publication date: March 13, 2014Applicant: Gambro Lundia ABInventors: Francesco Fontanazzi, Alessandro Surace, Francesco Paolini
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Publication number: 20140048460Abstract: A method to determine a type of blood circuit attached to an extracorporeal blood treatment console including: pumping a liquid through a blood passage of the blood circuit, sensing a first pressure in: the blood passage while the passage is closed and pumping stopped, pumping an additional amount of the liquid into the blood passage while the blood passage is and remains closed and thereafter sensing a second pressure, and determine a dimensional characteristic of a fluid passage in the blood passage based on the additional amount of the liquid and the second pressure.Type: ApplicationFiled: December 21, 2011Publication date: February 20, 2014Inventors: Francesco Paolini, Paolo Rovatti
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Publication number: 20110118647Abstract: An extracorporeal blood treatment apparatus comprises a sensor (10) for emitting a signal indicating a change of hematic volume of an individual (7) subjected to a treatment and a weight loss system for actuating the individual's weight loss. A control unit (20) receives an effective weight value of the individual and a desired weight loss value and from these values determines a desired value of a change in hematic volume at end of treatment. The weight loss system is controlled on a basis of the hematic volume change signal and the desired value of the hematic volume change. The apparatus enables automatic control of a dialysis operation while preventing some complications arising from hypotension.Type: ApplicationFiled: July 3, 2009Publication date: May 19, 2011Applicant: GAMBRO LUNDIA ABInventors: Francesco Paolini, Francesco Fontanazzi, Fabio Grandi
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Patent number: 7794419Abstract: The apparatus for blood flow control in an extracorporeal circuit comprises: a user interface for setting a desired blood flow value (qbREAL) and a datum relating to the vascular access, a memory for recording a plurality of mathematical relations having mathematical expressions relating to the vascular access organ to be used, and a control unit. The control unit identifies the vascular access, selects, from among the plurality of mathematical relations present in the memory, a relation which corresponds to the vascular access identified, and calculates, as a mathematical function of the set value for the desired flow (qbREAL), a value at which to set the angular velocity of the pump associated to the extracorporeal circuit and/or a theoretical value of the arterial pressure upstream of the pump.Type: GrantFiled: May 18, 2005Date of Patent: September 14, 2010Assignee: Gambro Lundia ABInventors: Francesco Paolini, Carlo Alberto Lodi, Francesco Fontanazzi
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Patent number: 7648474Abstract: A method of detecting the detachment of the venous needle from a patient during an extracorporeal blood treatment in a dialysis machine having an extracorporeal blood circuit provided with an arterial branch and a venous branch. The arterial pressure (Pa) is measured in the arterial branch and the venous pressure (Pv) is measured in the venous branch, and the determination is made of whether or not decreases of the arterial pressures (Pa) and venous pressures (Pv) are occurring during the dialysis treatment in normal conditions.Type: GrantFiled: June 24, 2002Date of Patent: January 19, 2010Assignee: Gambro Lundia ABInventors: Francesco Paolini, Carlo Alberto Lodi, Massimo Fava
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Patent number: 7648475Abstract: A non-invasive device for measuring blood temperature in a circuit for the extracorporeal circulation of blood includes a line in which blood taken from a patient flows. The device also includes a temperature sensor connected to the line and provided with a device for measuring the intensity of an electromagnetic radiation. The measuring device faces a connecting portion or window of the line that is permeable by electromagnetic radiation in a first wave band, and generates a first signal, correlated with the electromagnetic radiation in the first band and therefore with the temperature of the blood flowing in the line.Type: GrantFiled: December 20, 2002Date of Patent: January 19, 2010Assignee: Gambro Lundia ABInventors: Giorgio De Cicco, Francesco Fontanazzi, Annalisa Delnevo, Massimo Zaccarelli, Francesco Paolini
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Publication number: 20100000944Abstract: Control equipment for an extracorporeal blood circuit (2), in which the extracorporeal circuit (2) has an access branch (8) and a return branch (10) connected to a blood treatment element (4; 4, 11a; 4, 11v; 25; 25, 11a, 25, 11v), is provided with a sensor for measuring a first temperature (TP) of the blood leaving a patient (P) along the access branch (8), with a heat exchanger formed by a portion (19) of the return branch (10) and by a device for regulating the temperature (T) of the blood coupled to the portion (19) of the return branch (10), and with a control unit (15) for operating the regulating device (18) as a function of the first temperature (TP) and of a reference temperature (Tset).Type: ApplicationFiled: September 9, 2009Publication date: January 7, 2010Inventors: Francesco Paolini, Francesco Fontanazzi, Massimo Zaccarelli
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Publication number: 20080275377Abstract: The apparatus for blood flow control in an extracorporeal circuit comprises: a user interface for setting a desired blood flow value (qbREAL) and a datum relating to the vascular access, a memory for recording a plurality of mathematical relations having mathematical expressions relating to the vascular access organ to be used, and a control unit. The control unit identifies the vascular access, selects, from among the plurality of mathematical relations present in the memory, a relation which corresponds to the vascular access identified, and calculates, as a mathematical function of the set value for the desired flow (qbREAL), a value at which to set the angular velocity of the pump associated to the extracorporeal circuit and/or a theoretical value of the arterial pressure upstream of the pump.Type: ApplicationFiled: May 18, 2005Publication date: November 6, 2008Applicant: GAMBRO LUNDIA ABInventors: Francesco Paolini, Carlo Alberto Lodi, Francesco Fontanazzi
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Publication number: 20070265594Abstract: The invention concerns a fluid bag that contains either dialysis fluid for hemodialysis or a replacement fluid for replacing ultra-filtrate that is withdrawn from a patient or a fluid that is a rest product from a process of hemodialysis or the like. The fluid bag has a first main sheet and a second main sheet located opposite to the first main sheet. The fluid bag is sized to contain at least a certain quantity (q) of fluid, measured in ml, when it is completely filled with fluid. The fluid bag is configured so that the distance between the first and second sheets never exceeds a certain value (v), measured in mm, wherein: q?2000, and v?2q/100. The invention also concerns a fluid bag assembly including one or more such fluid bags as well as a system including one or more such fluid bags.Type: ApplicationFiled: February 10, 2005Publication date: November 15, 2007Inventors: Michaela Hagermark, Francesco Paolini
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Patent number: 7131956Abstract: A dialysis machine comprises: means for calculating (60) a filtration factor (FF) as a function of the ultrafiltration rate (UFR) and of a plasma flow rate (Qp); first comparison means (65) for comparing the filtration factor (FF) with a limit value of admissibility; and signaling means (70) for generating a signal (A) indicating the result of the comparison.Type: GrantFiled: July 28, 2000Date of Patent: November 7, 2006Assignee: Gambro Hospal Schweiz AGInventors: Paolo Pirazzoli, Antonio Bosetto, Francesco Paolini
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Publication number: 20060191850Abstract: A method for preparing a medical liquid from a liquid, such as water, and two concentrated solutions comprises the following steps: circulating the liquid in a conduit (15), at a flowrate Q0; injecting into the conduit (15), at a flowrate Q1, a first concentrated solution containing a first ionic substance A and a second ionic substance B, the ionic substances A and B having, respectively, in the first concentrated solution, a concentration [Asol] and a first concentration [B1sol]; injecting into the conduit (15), at a flowrate Q2, a second concentrated solution containing the first ionic substance A and the second ionic substance B, the first ionic substance A having, in the second concentrated solution, the same concentration [Asol] as in the first concentrated solution, and the second ionic substance B having, in the second concentrated solution, a second concentration [B2sol] different than the first concentration [B1sol] in the first concentrated solution; regulating the injection flowrate Q1 and tType: ApplicationFiled: April 12, 2006Publication date: August 31, 2006Inventors: Antonio Bosetto, Francesco Paolini
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Patent number: 7067061Abstract: A method for preparing a medical liquid from a liquid, such as water, and two concentrated solutions comprises the following steps: circulating the liquid in a conduit (15), at a flowrate Q0; injecting into the conduit (15), at a flowrate Q1, a first concentrated solution containing a first ionic substance A and a second ionic substance B, the ionic substances A and B having, respectively, in the first concentrated solution, a concentration [Asol] and a first concentration [B1sol]; injecting into the conduit (15), at a flowrate Q2, a second concentrated solution containing the first ionic substance A and the second ionic substance B, the first ionic substance A having, in the second concentrated solution, the same concentration [Asol] as in the first concentrated solution, and the second ionic substance B having, in the second concentrated solution, a second concentration [B2sol] different than the first concentration [B1sol] in the first concentrated solution; regulating the injection flowrate Q1 and theType: GrantFiled: May 13, 2004Date of Patent: June 27, 2006Assignee: Gambro Hospal (Schweiz) AGInventors: Antonio Bosetto, Francesco Paolini
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Patent number: 7060047Abstract: A method of sensing the detachment of the venous needle (13) from a patient (P) during an extracorporeal blood treatment in a dialysis machine (1) having an extracorporeal blood circuit (2), in which an electric current is made to flow along a closed-loop path (P1) of an electrical circuit (37) formed by an electrical line (21, 22, 23) external to the extracorporeal circuit (2), a portion of extracorporeal circuit (2) directly connected to the venous needle (13), and the patient (P); a signal correlated with the electric current along the electrical line (21, 22, 23) is detected; and the signal is compared with a threshold value by means of a control unit (15).Type: GrantFiled: May 30, 2002Date of Patent: June 13, 2006Assignee: Gambro Lundia ABInventors: Carlo Alberto Lodi, Francesco Paolini, Enrico Canini
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Patent number: 7001353Abstract: A method is described for determining recirculation of blood in a vascular access of a patient undergoing dialysis treatment using a dialysis machine with an arterial line for withdrawing blood from the patient's body, a dialysis filter, and a venous line for returning blood to the patient's body. The method induces a disturbance in the blood flowing in the venous line. The disturbance is of a magnitude capable of bringing the system into a transient state and determining blood recirculation in the vascular access during the transient state as a function of the magnitude of the disturbance induced in the arterial line. In particular, the disturbance relates to the variation of the hemoglobin concentration in the blood flowing in the venous line. The variation is caused by controlling a change in the ultrafiltration flow in the dialysis filter.Type: GrantFiled: December 18, 2000Date of Patent: February 21, 2006Assignee: Gambro Hospal (Scweiz) AGInventors: Antonio Bosetto, Francesco Paolini
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Publication number: 20050020958Abstract: Control equipment for an extracorporeal blood circuit (2), in which the extracorporeal circuit (2) has an access branch (8) and a return branch (10) connected to a blood treatment element (4; 4, 11a; 4, 11v; 25; 25, 11a; 25, 11v), is provided with a sensor for measuring a first temperature (TP) of the blood leaving a patient (P) along the access branch (8), with a heat exchanger formed by a portion (19) of the return branch (10) and by a device for regulating the temperature (T) of the blood coupled to the portion (19) of the return branch (10), and with a control unit (15) for operating the regulating device (18) as a function of the first temperature (TP) and of a reference temperature (Tset).Type: ApplicationFiled: December 20, 2002Publication date: January 27, 2005Inventors: Francesco Paolini, Francesco Fontanazzi, Massimo Zaccarelli
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Publication number: 20040206703Abstract: A method for preparing a medical liquid from a liquid, such as water, and two concentrated solutions comprises the following steps:Type: ApplicationFiled: May 13, 2004Publication date: October 21, 2004Applicant: Gambro Hospal (Schweiz) AGInventors: Antonio Bosetto, Francesco Paolini
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Patent number: 6793827Abstract: A method for extracorporeal treatment of blood includes preparing a treatment liquid from a liquid and two concentrated solutions by circulating the liquid in a preparation conduit at a flowrate Q0; injecting a first concentrated solution containing at least a first ionic substance A and a second ionic substance B into the preparation conduit at a flowrate Q1; and injecting a second concentrated solution containing at least the first ionic substance A into the preparation conduit at a flowrate Q2. The ionic substance B may have a first concentration in the first concentrated solution and a second concentration, different from the first concentration, in the second concentrated solution. The method may also include regulating the injection flowrates Q1 and Q2 in such a way that at any given time the diluted solution resulting from the mixing of the liquid and the concentrated solutions has a desired concentration of the first ionic substance A and a desired concentration of the second ionic substance B.Type: GrantFiled: October 9, 2001Date of Patent: September 21, 2004Assignee: Gambro Hospal AGInventors: Antonio Bosetto, Francesco Paolini
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Patent number: 6794194Abstract: A method for measuring the hemoglobin concentration in the blood in a circuit of a dialysis machine includes directing electromagnetic waves against one section of the circuit, measuring values of the electromagnetic waves transmitted through the section, and determining values of absorption of electromagnetic waves by the blood along the section from the measured values of transmitted electromagnetic waves. The values of absorption are correlated with the values of the hemoglobin concentration. The method also includes measuring the values of at least one physical quantity of the blood, wherein the at least one physical quantity is selected from blood pressure and blood temperature, and calculating the values of hemoglobin concentration as a function of the values of absorption and the at least one physical quantity.Type: GrantFiled: October 21, 2002Date of Patent: September 21, 2004Assignee: Gambro Dasco SpAInventors: Massimo Fava, Annalisa Delnevo, Francesco Paolini