Abstract: The invention relates to oral administration of biological actives, in particular of insulin, comprising the use of a cross-linked starchy material as a delivery system.

Abstract: The invention relates to oral administration of biological actives, in particular of insulin, comprising the use of a cross-linked starchy material as a delivery system.

Abstract: The invention relates a process for preparing a cross-linked starch-based polymer comprising the following steps: 1) dissolving a starchy material in a suitable solvent to form a starchy material solution; and 2) adding a episulfide of formula (I), wherein R1, R2, R3 and R4 are independently selected from hydrogen and (C1-C3)alkyl in the starchy material solution in order to obtain the disulfide crosslinked starch-based polymer. In another aspect the invention concerns a disulfide-cross-linked starch-based polymer obtainable by the process of the invention, that is characterized by only disulfide bridges.

Abstract: The invention relates a process for preparing a cross-linked starch-based polymer comprising the following steps: 1) dissolving a starchy material in a suitable solvent to form a starchy material solution; and 2) adding a episulfide of formula (I), wherein R1, R2, R3 and R4 are independently selected from hydrogen and (C1-C3)alkyl in the starchy material solution in order to obtain the disulfide crosslinked starch-based polymer. In another aspect the invention concerns a disulfide-cross-linked starch-based polymer obtainable by the process of the invention, that is characterized by only disulfide bridges.

Abstract: Novel anti-tumor agents comprising at least one ligand of the B7h receptor, wherein the ligand of receptor B7h is loaded in a biocompatible micro- or nano-carrier and is able of binding to receptor B7h and triggering receptor B7h activity.

Abstract: The invention relates to oral administration of biological actives, in particular of insulin, comprising the use of a cross-linked starchy material as a delivery system.

Abstract: The invention relates a process for preparing a microporous carbon material comprising the following steps: i) providing a cross-linked polymer obtainable by reacting either A1) a maltodextrin deriving from starch comprising amylose in the range from 25 to 50% expressed as dry weight relative to the dry weight of the starch or A2) a cyclodextrin with an organic aromatic dianhydride in a mass ratio of either maltodextrin or cyclodextrin with respect to the organic aromatic dianhydride in the range of 1:0.50 to 1:2, ii) pyrolyzing at a range from 700 to 900° C. with a heating ramp in the range from 5° C./min to 30° C./min in a inert gas flux; and iii) cooling the obtained residue. The microporous carbon material obtainable by the process of the invention consists of micropores having pore size distribution in the range from about 6 to about 16 ? and is used as absorber for liquids and gases.

Abstract: The invention relates a cross-linked polymer obtainable by reacting a maltodextrin deriving from starch comprising amylose in the range from 25 to 50% expressed as dry weight relative to the dry weight of the starch and at least one cross-linking compound having a electropositive carbon atom selected from the group consisting of a dicarboxylic acid, dianhydride, carbonyldiimidazole, diphenylcarbonate, triphosgene, acylic dichloride, diisocyanate, diepoxide The polymer of the invention can be used for the encapsulation/inclusion/entrapment of an organic compound.

Abstract: The invention relates a process for preparing a microporous carbon material comprising the following steps: i) providing a cross-linked polymer obtainable by reacting either A1) a maltodextrin deriving from starch comprising amylose in the range from 25 to 50% expressed as dry weight relative to the dry weight of the starch or A2) a cyclodextrin with an organic aromatic dianhydride in a mass ratio of either maltodextrin or cyclodextrin with respect to the organic aromatic dianhydride in the range of 1:0.50 to 1:2, ii) pyrolyzing at a range from 700 to 900° C. with a heating ramp in the range from 5° C./min to 30° C./min in a inert gas flux; and iii) cooling the obtained residue. The microporous carbon material obtainable by the process of the invention consists of micropores having pore size distribution in the range from about 6 to about 16 ? and is used as absorber for liquids and gases.

Abstract: A positioning system for radio frequency devices includes a two-way radio antenna, for vehicles, having a transmitting and a receiving element. Reference antennas have retro-directive arrays which can shape the signal beams in elevation; polarize transmission and reception signals according to a circular or a linear polarization, the polarized transmission retro-directively reflecting signals having the same polarization as the incident ones in the case of circular polarization, or retro-directively reflecting signals having orthogonal polarization in the case of linear polarization. An encoder is included for transmitting an identification code of the reference antenna. A controller processes the spatial and temporal data resulting from communication through the radio waves transmitted and received by the vehicle antennas and reflected by the reference antennas. The controller calculates the distance of the vehicle from the reference antennas that have reflected the signal transmitted by the antennas.

Abstract: Hyperbranched, water-soluble polymers, obtainable by Michael polyaddition of ?-, ?-, or ?-cyclodextrins and amines to bisacrylamides.

Abstract: A positioning system for radio frequency devices includes a two-way radio antenna, for vehicles, having a transmitting and a receiving element. Reference antennas have retro-directive arrays which can shape the signal beams in elevation; polarize transmission and reception signals according to a circular or a linear polarization, the polarized transmission retro-directively reflecting signals having the same polarization as the incident ones in the case of circular polarisation, or retro-directively reflecting signals having orthogonal polarisation in the case of linear polarisation. An encoder is included for transmitting an identification code of the reference antenna. A controller processes the spatial and temporal data resulting from communication through the radio waves transmitted and received by the vehicle antennas and reflected by the reference antennas. The controller calculates the distance of the vehicle from the reference antennas that have reflected the signal transmitted by the antennas.

Abstract: Hyperbranched, water-soluble polymers, obtainable by Michael polyaddition of ?-, ?-, or ?-cyclodextrins and amines to bisacrylamides.

Abstract: This invention provides novel aryl piperazine derivatives having medical utility, in particular as modulators of dopamine and serotonin receptors, preferably the D3, D2-like and 5-HT2 receptor subtypes, and in particular useful for the treatment of neuropsychiatric disorders incl. schizophrenia.

Abstract: A description is given of substantially spherical nanosponges which can be obtained by crosslinking cyclodextrins and their by-products with organic carbonates as crosslinkers and ultrasounds without a solvent.

Abstract: Cyclodextrins cross-linked by reaction with organic carbonates and the use thereof as agents capable or removing pollutants from fluids of various origin, in particular from contaminated waters.