Abstract: An example medical device is disclosed. The medical device includes a delivery shaft and a frame. The frame is coupled to the distal portion of the delivery shaft, and the frame includes a body portion and at least first and second arms. Each arm has a first end attached to the body portion and a second, free end opposite the first end. The frame includes tabs on the arms and body portion configured to removably couple to an implant. The tabs on the arms and body portion may extend in different directions.

Abstract: Implant delivery systems are disclosed. One implant delivery system includes an outer shaft, an inner shaft movable within the outer shaft, a yoke coupled to the distal end of the inner shaft, and an implant retainer pivotably coupled to the yoke. The implant retainer is configured to retain a sheet-like implant for implantation at a treatment site. Another implant delivery system includes a handle, a delivery sheath extending from the handle, and a delivery shaft extending through the delivery sheath to a frame attachable to a sheet-like implant. A tether extends from the frame within the lumen of the delivery shaft. An actuation member is translatable within a channel of the handle to deploy the frame from the delivery sheath. A tether clamp, positioned within the handle, is manipulatable by the actuation member to selectively unlock the tether within the handle.

Abstract: A cannula for passing surgical instruments through tissue. In some instances, the cannula may include a distal flange flexible between a radial configuration and a longitudinal configuration. In some instances, the cannula may also include an actuator configured to move the distal flange between the radial configuration and the longitudinal configuration. In some instances, the cannula may include a valve disposed within the lumen of the cannula, and a cap configured to secure the valve to the cannula. The valve may include a body member having a base and first and second opposing walls extending from the base. In some instances, the valve has an arcuate cutout in the lower surface configured to fit around an instrument shaft inserted therethrough. In some instance, the cannula includes a slit extending an entire length of the cannular to permit an instrument shaft to be inserted and/or removed laterally.

Abstract: Devices and methods for automated liquid handling and reagent processing to provide labelling and detection of bacteria and viruses are provided. Labelling reactions are performed rapidly and with essentially no generation of hazardous waste or use of consumables. Highly sensitive detection is performed by measuring fluorescence on a rotating sample plate.

Abstract: Disclosed herein is an inflow cannula for an implantable blood pump assembly. The inflow cannula includes a tubular body that extends from a proximal end to a distal end. The tubular body includes a proximal portion adapted for connection to a pump housing, and a distal portion adapted for positioning within an opening formed in a heart. The inflow cannula further includes an expandable sleeve coupled to an exterior surface of the distal portion. The sleeve has a first portion coupled to the distal portion of the tubular body, and a second portion extending from the distal end of the tubular body. The second portion is deployable from a first, stored configuration to a second, deployed configuration in which the second portion expands radially to engage and conform to an endocardial surface of the heart.

Abstract: Disclosed herein is an inflow cannula for an implantable blood pump assembly. The inflow cannula includes a tubular body that extends from a proximal end to a distal end. The tubular body includes a proximal portion adapted for connection to a pump housing, and a distal portion adapted for positioning within an opening formed in a heart. The inflow cannula further includes an expandable sleeve coupled to an exterior surface of the distal portion. The sleeve has a first portion coupled to the distal portion of the tubular body, and a second portion extending from the distal end of the tubular body. The second portion is deployable from a first, stored configuration to a second, deployed configuration in which the second portion expands radially to engage and conform to an endocardial surface of the heart.