Patents by Inventor Francine Gervais

Francine Gervais has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140329746
    Abstract: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.
    Type: Application
    Filed: July 16, 2014
    Publication date: November 6, 2014
    Inventors: Xianqi Kong, Xinfu Wu, Abderrahim Bouzide, Isabelle Valade, David Migneault, Francine Gervais, Daniel Delorme, Benoit Bachand, Mohamed Atfani, Sophie Levesque, Bita Samim
  • Patent number: 8835654
    Abstract: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.
    Type: Grant
    Filed: September 20, 2011
    Date of Patent: September 16, 2014
    Assignee: BHI Limited Partnership
    Inventors: Xianqi Kong, Xinfu Wu, Abderrahim Bouzide, Isabelle Valade, David Migneault, Francine Gervais, Daniel Delorme, Benoit Bachand, Mohamed Atfani, Sophie Levesque, Bita Samim
  • Publication number: 20140107027
    Abstract: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.
    Type: Application
    Filed: December 18, 2013
    Publication date: April 17, 2014
    Applicant: BHI LIMITED PARTNERSHIP
    Inventors: Xianqi Kong, David Migneault, Isabelle Valade, Xinfu Wu, Francine Gervais
  • Patent number: 8642801
    Abstract: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.
    Type: Grant
    Filed: November 5, 2009
    Date of Patent: February 4, 2014
    Assignee: BHI Limited Partnership
    Inventors: Xianqi Kong, David Migneault, Isabelle Valade, Xinfu Wu, Francine Gervais
  • Publication number: 20120015911
    Abstract: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.
    Type: Application
    Filed: September 20, 2011
    Publication date: January 19, 2012
    Applicant: Bellus Health Inc.
    Inventors: Xianqi Kong, Xinfu Wu, Abderrahim Bouzide, Isabelle Valade, David Migneault, Francine Gervais, Daniel Delorme, Benoit Bachand, Mohamed Atfani, Sophie Levesque, Bita Samim
  • Patent number: 8044100
    Abstract: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: October 25, 2011
    Assignee: Bellus Health Inc.
    Inventors: Xianqi Kong, Xinfu Wu, Abderrahim Bouzide, Isabelle Valade, David Migneault, Francine Gervais, Daniel Delorme, Benoit Bachand, Mohamed Atfani, Sophie Levesque, Bita Samim
  • Publication number: 20100190753
    Abstract: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-+related disease.
    Type: Application
    Filed: August 27, 2009
    Publication date: July 29, 2010
    Applicant: BELLUS Health (International) Limited
    Inventors: Xianqi KONG, Walter A. Szarek, Francine Gervais
  • Publication number: 20100113591
    Abstract: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.
    Type: Application
    Filed: November 5, 2009
    Publication date: May 6, 2010
    Applicant: BELLUS Health (International) Limited
    Inventors: Xianqi Kong, David Migneault, Isabelle Valade, Xinfu Wu, Francine Gervais
  • Patent number: 7598269
    Abstract: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-+related disease.
    Type: Grant
    Filed: May 30, 2007
    Date of Patent: October 6, 2009
    Assignee: Bellus Health (International) Limited
    Inventors: Xianqi Kong, Walter A. Szarek, Francine Gervais
  • Publication number: 20080317834
    Abstract: The invention provides methods of inhibiting cerebral amyloid angiopathy. The invention further provides methods of treating a disease state characterized by cerebral amyloid angiopathy in a subject.
    Type: Application
    Filed: November 10, 2003
    Publication date: December 25, 2008
    Applicant: Neurochem (International) Limited
    Inventors: Allan M. Green, Francine Gervais
  • Publication number: 20080249184
    Abstract: The invention provides methods of inhibiting A?-induced neuronal cell death. The invention further provides methods of providing neuroprotection to a subject and methods of treating a disease state characterized by A?-induced neuronal cell death in a subject. Methods of inhibiting p75 receptor mediated neuronal cell death, as well as methods of treating a disease state in a subject characterized by p75 receptor mediated neuronal cell death are provided.
    Type: Application
    Filed: June 9, 2008
    Publication date: October 9, 2008
    Applicant: Bellus Health (International) Limited
    Inventors: Francine Gervais, Louis R. Lamontagne
  • Patent number: 7414076
    Abstract: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: August 19, 2008
    Assignee: Neurochem (INTERNATIONAL) Limited
    Inventors: Xianqi Kong, David Migneault, Isabelle Valade, Xinfu Wu, Francine Gervais
  • Publication number: 20080038192
    Abstract: Described are methods of assessing whether a subject has or is at risk of having multiple organ amyloidosis (MOA) The method includes detecting a diagnostically predictive collection of biomarkers of multiple organ amyloidosis, wherein the detection of a diagnostically predictive collection of biomarkers indicates the subject has or is at risk of having multiple organ amyloidosis Also described are methods of monitoring treatment of subjects with multiple organ amyloidosis and evaluating therapeutic compounds Representative biomarkers for use in the methods may be selected from variant serum amyloid A (SAA) allele, elevated SAA level, elevated C-reactive protein (CRP) level, depressed glycosammoglycan (GAG) level, elevated interleukin-18 (IL-18) level, elevated macrophage-colony stimulating factor (M-CSF) level, elevated hepatocyte growth factor (HGF) level, presence of an antibody against citrullmated vimentm (Sa), presence of a monoclonal immunoglobulin light chain, increased serum albumin, and increased cr
    Type: Application
    Filed: July 18, 2005
    Publication date: February 14, 2008
    Applicant: NEUROCHEM INC.
    Inventor: Francine Gervais
  • Publication number: 20080015180
    Abstract: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-+related disease.
    Type: Application
    Filed: May 30, 2007
    Publication date: January 17, 2008
    Applicant: Neurochem (International) Limited
    Inventors: Xianqi Kong, Walter Szarek, Francine Gervais
  • Patent number: 7311893
    Abstract: Amyloid-targeting imaging agents such as radiolabeled amyloid targeting molecules and amyloid targeting molecule-chelator conjugates for imaging, e.g., amyloid plaques in vivo, and/or for the treatment of amyloidosis disorders. The invention provides amyloid-targeting imaging agents that are useful for imaging sites of amyloid disease. Imaging agents of the invention are capable of binding specifically to amyloid plaques, as an aid in diagnosis and/or early treatment of amyloidosis disorders.
    Type: Grant
    Filed: December 3, 2003
    Date of Patent: December 25, 2007
    Assignee: Neurochem (International) Limited
    Inventors: Francine Gervais, Xianqi Kong, Robert Chalifour, David Migneault
  • Publication number: 20070264276
    Abstract: The present invention relates to a stereochemically based “non-self” antigen vaccine for the prevention and/or treatment of Alzheimer's and other amyloid related diseases. The present invention provides a vaccine for the prevention and treatment of Alzheimer's and other amyloid related diseases, which overcomes the drawbacks associated with using naturally occurring peptides, proteins or immunogens.
    Type: Application
    Filed: July 21, 2004
    Publication date: November 15, 2007
    Inventors: Robert Chalifour, Lise Hebert, Xianqi Kong, Francine Gervais
  • Patent number: 7244764
    Abstract: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-+related disease.
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: July 17, 2007
    Assignee: Neurochem (International) Limited
    Inventors: Xianqi Kong, Walter A. Szarek, Francine Gervais
  • Publication number: 20070135337
    Abstract: The present invention relates to a stereochemically based “non-self” antigen vaccine for the prevention and/or treatment of Alzheimer's and other amyloid related diseases. The present invention provides a vaccine for the prevention and treatment of Alzheimer's and other amyloid related diseases, which overcomes the drawbacks associated with using naturally occurring peptides, proteins or immunogens.
    Type: Application
    Filed: April 16, 2004
    Publication date: June 14, 2007
    Applicant: Neurochem (International) Limited
    Inventors: Robert Chalifour, Lise Hebert, Xianqi Kong, Francine Gervais
  • Publication number: 20070078082
    Abstract: Therapeutic compounds and methods for inhibiting a glycosaminoglycan (GAG)-associated molecular interaction in a subject, whatever its clinical setting, are described
    Type: Application
    Filed: September 19, 2006
    Publication date: April 5, 2007
    Applicants: Neurochem (International) Limited, Queen's University at Kingston
    Inventors: Robert Kisilevsky, Allan Green, Francine Gervais
  • Publication number: 20070010573
    Abstract: Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.
    Type: Application
    Filed: December 21, 2005
    Publication date: January 11, 2007
    Inventors: Xianqi Kong, David Migneault, Isabelle Valade, Xinfu Wu, Francine Gervais