Abstract: An internal combustion engine for use with a propeller driven aircraft includes a camshaft adapted to function as an output shaft that rotates a propeller to provide propulsive thrust. A gear set is configured to transfer rotational power from the crankshaft to the camshaft and to rotate the camshaft at a velocity that is proportional to the rotational velocity of the crankshaft. The gear set is disposed rearward of the engine housing rearward wall and is configured to rotate the camshaft in a direction opposite the crankshaft rotation. The length of the camshaft reduces engine torsional vibration. In one embodiment, the engine is a six-cylinder compression ignition engine having a boxer configuration and can generate a peak output power within a range from about 300 horsepower to about 350 horsepower.

Abstract: An internal combustion engine for use with a propeller driven aircraft includes a camshaft adapted to function as an output shaft that rotates a propeller to provide propulsive thrust. A gear set is configured to transfer rotational power from the crankshaft to the camshaft and to rotate the camshaft at a velocity that is proportional to the rotational velocity of the crankshaft. The gear set is disposed rearward of the engine housing rearward wall and is configured to rotate the camshaft in a direction opposite the crankshaft rotation. The length of the camshaft reduces engine torsional vibration. In one embodiment, the engine is a six-cylinder compression ignition engine having a boxer configuration and can generate a peak output power within a range from about 300 horsepower to about 350 horsepower.

Abstract: The level of the leukemic lymphocytes in patients suffering from chronic lymphocytic leukemia (CLL) is reduced by the administration of certain indole or carbazole compounds, such as the nonsteroidal anti-inflammatory drug etodolac or related indole or carbazol compounds.

Abstract: The level of the leukemic lymphocytes in patients suffering from chronic lymphocytic leukemia (CLL) is reduced by the administration of certain indole or carbazole compounds, such as the nonsteroidal anti-inflammatory drug etodolac or related indole or carbazole compounds.

Abstract: The level of the leukemic lymphocytes in patients suffering from chronic lymphocytic leukemia (CLL) is reduced by the administration of certain indole or carbazole compounds, such as the nonsteroidal anti-inflammatory drug etodolac or related indole or carbazole compounds.

Abstract: Methods for the treatment of Chronic Lymphocytic Leukemia and B-cell and T-cell lymphomas are provided. These methods comprise administering to a patient in need of treatment an effective amount of certain indole and carbazole compounds, such as etodolac.