Patents by Inventor Francis Barth

Francis Barth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Derivatives of 4,5-diarylpyrrole, preparation method thereof and use of same in therapeutics
    Patent number: 7618995
    Abstract: The invention relates to compounds having formula (I): Wherein X, R1, R2, R3, R4 and R5 are as defined herein. The invention also relates to the preparation method thereof and the use of same in therapeutics.
    Type: Grant
    Filed: December 7, 2007
    Date of Patent: November 17, 2009
    Assignee: Sanofi-Aventis
    Inventors: Francis Barth, Christian Congy, Laurent Hortala, Murielle Rinaldi-Carmona
  • Heterocyclic derivatives, preparation and therapeutic use thereof
    Patent number: 7618991
    Abstract: The invention concerns compounds of formula (I): Wherein X, Y, R1, R2, R3 and R4 are as described herein. The invention also concerns a method for preparing same and the therapeutic use thereof.
    Type: Grant
    Filed: May 23, 2008
    Date of Patent: November 17, 2009
    Assignee: Sanofi-Aventis
    Inventors: Francis Barth, Murielle Rinaldi-Carmona
  • PYRROLE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF
    Publication number: 20090281116
    Abstract: The invention relates to compounds having the formula (I): Wherein R1, R2, R3, R4, R5, R6, R7 and R9 and A-R9 are as defined herein. Also disclosed are the preparative methods for the compounds of formula (I) and their use in therapy.
    Type: Application
    Filed: May 14, 2009
    Publication date: November 12, 2009
    Applicant: SANOFI-AVENTIS
    Inventors: Francis Barth, Christian Congy, Laurent Hortala, Murielle Rinaldi-Carmona
  • N-[(4,5-diphenyl-2-thienyl)methyl]sulfonamide derivatives, preparation thereof and their therapeutic application
    Patent number: 7589120
    Abstract: The invention relates to compounds of formula (I): Wherein X, R1, R2, R3 and R4 are as described herein. The invention also relates to a method for preparing the aforementioned compounds and to their therapeutic application.
    Type: Grant
    Filed: July 10, 2007
    Date of Patent: September 15, 2009
    Assignee: Sanofi-Aventis
    Inventors: Francis Barth, Christian Congy, Jean-Philippe Ducoux, Murielle Rinaldi-Carmona
  • AMINOMETHYLPYRIDINE DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF
    Publication number: 20090203699
    Abstract: The present invention pertains to aminomethylpyridine derivatives, to their preparation and to their therapeutic application.
    Type: Application
    Filed: October 10, 2008
    Publication date: August 13, 2009
    Inventors: Francis Barth, Christian Congy, Philippe Pointeau, Murielle Rinaldi-Camona, Lionel Barre
  • N-[4,5-diphenylpyrimidin-2-yl)methyl]amine derivatives, the preparation thereof and their therapeutic use
    Patent number: 7541361
    Abstract: The invention relates to compounds of formula (I): Wherein X, R1, R2, R3, R4 and R5 are as defined herein. The invention also relates to a method for preparing the aforementioned compounds and to their therapeutic use.
    Type: Grant
    Filed: January 3, 2008
    Date of Patent: June 2, 2009
    Assignee: Sanofi-Aventis
    Inventors: Francis Barth, Christian Congy, Patrick Gueule, Murielle Rinaldi-Carmona
  • 1,5-diarylpyrrole derivatives, preparation method thereof and application of same in therapeutics
    Patent number: 7524971
    Abstract: The invention relates to compounds having formula (I): Wherein X, R1, R2, R3, R4, R5 and R6 are as defined herein. The invention also relates to a method of preparing said compounds and to die application thereof in therapeutics.
    Type: Grant
    Filed: August 2, 2007
    Date of Patent: April 28, 2009
    Assignee: Sanofi - Aventis
    Inventors: Francis Barth, Christian Congy, Laurent Hortala, Murielle Rinaldi-Carmona
  • 4-cyanopyrazole-3-carboxamide derivatives, preparation and application thereof
    Patent number: 7521471
    Abstract: The invention relates to 4-cyanopyrazole-3-carboxamide derivatives of formula (I): in which R1, R2, R3, R4, R5, R6, R7, R8 are as described herein. Also disclosed and claimed are the method of preparation and therapeutic application of compound of formula (I).
    Type: Grant
    Filed: August 1, 2007
    Date of Patent: April 21, 2009
    Assignee: Sanofi-Aventis
    Inventors: Francis Barth, Christian Congy, Serge Martinez, Murielle Rinaldi-Carmona
  • Thiophene-2-carboxamide derivatives, preparation and therapeutic application thereof
    Patent number: 7462631
    Abstract: The invention discloses and claims a compound of formula (I): Wherein R1, R2, R3, R4, R5, R6, R7, R8 and R11 are as defined herein. Further embodiments of the invention include a method of preparation of a compound of formula (I), its pharmaceutical composition and a method of treatment of a disease using a compound of formula (I).
    Type: Grant
    Filed: April 7, 2006
    Date of Patent: December 9, 2008
    Assignee: Sanofi-Aventis
    Inventors: Francis Barth, Jean-Philippe Ducoux, Murielle Rinaldi-Carmona, Christian Congy
  • DIARYLTRIAZOLMETHYLAMINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF
    Publication number: 20080293794
    Abstract: The invention concerns compounds of formula (I): Wherein X, R1, R2, R3 and R4 are as described herein. The invention also concerns a method for preparing same and the therapeutic use thereof.
    Type: Application
    Filed: May 22, 2008
    Publication date: November 27, 2008
    Applicant: SANOFI-AVENTIS
    Inventors: Francis BARTH, Murielle RINALDI-CARMONA
  • 3-ACYLINDOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF
    Publication number: 20080275102
    Abstract: The invention relates to compounds of formula (I), wherein X, R1, R2, R3, R4 and R5 are as described herein. The invention also includes preparative methods for the preparation of compounds of formula (I). A method for the therapeutic use of the inventive compounds is also disclosed and claimed.
    Type: Application
    Filed: May 14, 2008
    Publication date: November 6, 2008
    Applicant: SANOFI-AVENTIS
    Inventors: Francis BARTH, Claude VERNHET, Murielle RINALDI-CARMONA, Carole Elisabeth GUILLAUMONT-LEGEAY
  • HETEROCYCLIC DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF
    Publication number: 20080269303
    Abstract: The invention concerns compounds of formula (I): Wherein X, Y, R1, R2, R3 and R4 are as described herein. The invention also concerns a method for preparing same and the therapeutic use thereof.
    Type: Application
    Filed: May 23, 2008
    Publication date: October 30, 2008
    Applicant: SANOFI-AVENTIS
    Inventors: Francis BARTH, Murielle RINALDI-CARMONA
  • PYRROLE DERIVATIVES, INTERMEDIATES THEREFOR, PREPARATION AND THERAPEUTIC USE THEREOF
    Publication number: 20080194581
    Abstract: The invention concerns compounds of formula (I): Wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined herein. The invention also concerns the method for preparing said compounds including the intermediates therefor and their therapeutic use.
    Type: Application
    Filed: April 14, 2008
    Publication date: August 14, 2008
    Applicant: SANOFI-AVENTIS
    Inventors: Francis BARTH, Christian CONGY, Laurent HORTALA, Murielle RINALDI-CARMONA
  • DERIVATIVES OF 4,5-DIARYLPYRROLE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS
    Publication number: 20080176924
    Abstract: The invention relates to compounds having formula (I): Wherein X, R1, R2, R3, R4 and R5 are as defined herein. The invention also relates to the preparation method thereof and the use of same in therapeutics.
    Type: Application
    Filed: December 7, 2007
    Publication date: July 24, 2008
    Applicant: SANOFI-AVENTIS
    Inventors: Francis BARTH, Christian CONGY, Laurent HORTALA, Murielle RINALDI-CARMONA
  • N-[(4,5-DIPHENYLPYRIMIDIN-2-YL)METHYL]AMINE DERIVATIVES, THE PREPARATION THEREOF AND THEIR THERAPEUTIC USE
    Publication number: 20080176867
    Abstract: The invention relates to compounds of formula (I): Wherein X, R1, R2, R3, R4 and R5 are as defined herein. The invention also relates to a method for preparing the aforementioned compounds and to their therapeutic use.
    Type: Application
    Filed: January 3, 2008
    Publication date: July 24, 2008
    Applicant: SANOFI-AVENTIS
    Inventors: Francis BARTH, Christian CONGY, Patrick GUEULE, Murielle RINALDI-CARMONA
  • Terphenyl derivatives, preparation thereof, compositions containing same
    Patent number: 7390924
    Abstract: The invention relates to terphenyl derivatives of formula: and to their preparation and to the pharmaceutical compositions comprising them. These compounds exhibit an antagonist activity with respect to CB1 cannabinoid receptors.
    Type: Grant
    Filed: April 10, 2003
    Date of Patent: June 24, 2008
    Assignee: Sanofi-Aventis
    Inventors: Francis Barth, Serge Martinez, Murielle Rinaldi-Carmona
  • Pyrazolecarboxylic acid tricyclic derivatives, preparation and pharmaceutical compositions containing same
    Patent number: 7384960
    Abstract: The subject of the invention is tricyclic derivatives of pyrazolecarboxylic acid of formula: in which R1 represents a C3-C15 carboxyl radical or an NR2R3 group. The invention also relates to the method for preparing the compounds of formula (I), pharmaceutical compositions containing them. The compounds of formula (I) are active on cannabinoid CB1 receptors.
    Type: Grant
    Filed: April 29, 2005
    Date of Patent: June 10, 2008
    Assignee: Sanofi-Aventis
    Inventors: Francis Barth, Christian Congy, Serge Martinez, Murielle Rinaldi
  • Pyrrole derivatives, their preparation and their therapeutic use
    Patent number: 7381727
    Abstract: The invention concerns compounds of formula (I): Wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined herein. The invention also concerns the method for preparing said compounds and their therapeutic use.
    Type: Grant
    Filed: January 22, 2007
    Date of Patent: June 3, 2008
    Assignee: Sanofi-Aventis
    Inventors: Francis Barth, Christian Congy, Laurent Hortala, Murielle Rinaldi-Carmona
  • DERIVATIVES OF N-[(1,5-DIPHENYL-1H-PYRAZOL-3-YL)METHYL] SULFONAMIDE, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS
    Publication number: 20080070962
    Abstract: The present invention relates to compounds corresponding to the formula (I): In which R1, R2, R3, R4 and R5 are as described herein. The invention also relates to the method of preparation of said compounds and their application in therapeutics.
    Type: Application
    Filed: September 21, 2007
    Publication date: March 20, 2008
    Applicant: SANOFI-AVENTIS
    Inventors: Francis Barth, Christian Congy, Serge Martinez, Philippe Pointeau, Murielle Rinaldi-Carmona
  • Diphenylpyridine derivatives, preparation and therapeutic application thereof
    Patent number: 7345059
    Abstract: The invention relates to 5,6-diphenylpyridine-3-carboxamide derivatives of general formula (I): where: R1 represents hydrogen or a (C1-C4)alkyl; R2 represents: a monoazo saturated heterocycle of 5 to 7 atoms, the nitrogen atom being substituted with a (C1-C4)alkanoyl; NR10R11; a nonaromatic (C3-C10) carbocycle more than tri-substituted with (C1-C4)alkyl; a nonaromatic (C11-C12) carbocycle unsubstituted or mono- or polysubstituted with (C1-C4)alkyl; a monooxygenated saturated heterocycle with 5 to 7 atoms, more than tri-substituted with (C1-C4)alkyl; or R1 and R2, together with the nitrogen atom to which the above are bonded, form a 4-disubstituted piperidin-1-yl group; the salts, solvates and hydrates thereof. The invention further relates to a method for production and therapeutic application thereof.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: March 18, 2008
    Assignee: Sanofi-Aventis
    Inventors: Francis Barth, Laurent Hortala, Murielle Rinaldi-Carmona