Patents by Inventor Francis Bitsch

Francis Bitsch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of identifying ligands for nuclear receptors
    Publication number: 20050176062
    Abstract: The present invention provides a method of identifying a ligand to a nuclear receptor protein comprising wherein said nuclear receptor protein is first expressed in an eukaryotic expression system in the presence of at least one candidate ligand. The nuclear receptor protein is then purified, isolated and mass spectrometry is used to determine the presence of a bound ligand. The ligand is finally isolated and the measured spectra is compared with the spectra of known ligands in compound libraries to identify the ligand.
    Type: Application
    Filed: April 28, 2003
    Publication date: August 11, 2005
    Inventors: Reiner Aichholz, Francis Bitsch, Sabine Geisse, Jean-Marc Schlaeppi