Patents by Inventor Francis Daly
Francis Daly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190314459Abstract: The present invention refers to a GPR101 inhibitor, antagonist or inverse agonist or inverse agonist for use in preventive and/or therapeutic treatment of diseases selected from the group consisting of acromegaly and gigantism and to methods for preventive and/or therapeutic treatment of diseases selected from the group consisting of acromegaly and gigantism. Further, the present invention provides a GPR101 agonist for use in preventive and/or therapeutic treatment of disorders selected from the group consisting of dwarfism, short stature, hypopituitarism and a disease of low levels of pituitary hormone secretion and to methods for preventive and/or therapeutic treatment of diseases selected from the group consisting of dwarfism, short stature, hypopituitarism and a disease of low levels of pituitary hormone secretion wherein to a subject GPR101 agonist is administered.Type: ApplicationFiled: June 3, 2019Publication date: October 17, 2019Applicants: The United States of America, as represented by the Secretary, Department of Health and Human Servic, UNIVERSITE DE LIEGE, CENTRE HOSPITALIER UNIVERSITAIRE DE LIEGEInventors: Albert Beckers, Adrian Francis Daly, Fabio Rueda Faucz, Constantine A. Stratakis, Giampaolo Trivellin
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Patent number: 10350273Abstract: The present invention refers to a GPR101 inhibitor, antagonist or inverse agonist or inverse agonist for use in preventive and/or therapeutic treatment of diseases selected from the group consisting of acromegaly and gigantism and to methods for preventive and/or therapeutic treatment of diseases selected from the group consisting of acromegaly and gigantism. Further, the present invention provides a GPR101 agonist for use in preventive and/or therapeutic treatment of disorders selected from the group consisting of dwarfism, short stature, hypopituitarism and a disease of low levels of pituitary hormone secretion and to methods for preventive and/or therapeutic treatment of diseases selected from the group consisting of dwarfism, short stature, hypopituitarism and a disease of low levels of pituitary hormone secretion wherein to a subject GPR101 agonist is administered.Type: GrantFiled: November 12, 2015Date of Patent: July 16, 2019Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, Université de Liége and Centre Hospitalier Universitaire De LiégeInventors: Albert Beckers, Adrian Francis Daly, Fabio Rueda Faucz, Constantine A. Stratakis, Giampaolo Trivellin
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Patent number: 9893364Abstract: A new electroless plating approach to generate a porous metallic coating is described in which a metal is electrolessly deposited on a surface. Microparticles in the metal are removed to leave pores in the metal coating. Another method of forming electroless coatings is described in which a blocking ligand is attached to the surface, followed by a second coating step. The invention includes coatings and coated apparatus formed by methods of the invention. The invention also includes catalyst structures comprising a dense substrate and a porous metal adhered to the dense substrate, which is further characterized by one or more of the specified features.Type: GrantFiled: June 17, 2015Date of Patent: February 13, 2018Assignee: Velocys, Inc.Inventors: Richard Q. Long, Francis Daly, Haibiao Chen, Terry J. Mazanec
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Publication number: 20170304405Abstract: The present invention refers to a GPR101 inhibitor, antagonist or inverse agonist or inverse agonist for use in preventive and/or therapeutic treatment of diseases selected from the group consisting of acromegaly and gigantism and to methods for preventive and/or therapeutic treatment of diseases selected from the group consisting of acromegaly and gigantism wherein to a subject GPR101 inhibitor, antagonist or inverse agonist is administered. Further, the present invention provides a GPR101 agonist for use in preventive and/or therapeutic treatment of disorders selected from the group consisting of dwarfism, short stature, hypopituitarism and a disease of low levels of pituitary hormone secretion and to methods for preventive and/or therapeutic treatment of diseases selected from the group consisting of dwarfism, short stature, hypopituitarism and a disease of low levels of pituitary hormone secretion wherein to a subject GPR101 agonist is administered.Type: ApplicationFiled: November 12, 2015Publication date: October 26, 2017Applicants: The United States of America, as represented by the Secretary, Department of Health and Human, UNIVERSITE DE LIEGE, CENTRE HOSPITALIER UNIVERSITAIRE DE LIEGEInventors: Albert Beckers, Adrian Francis Daly, Fabio Rueda Faucz, Constantine A. Stratakis, Giampaolo Trivellin
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Patent number: 9656247Abstract: A method for the preparation of a modified catalyst support comprising: (a) treating a bare catalyst support material with an aqueous solution or dispersion of one or more titanium metal sources and one or more carboxylic acids; and (b) drying the treated support, and (c) optionally calcining the treated support. Also provided are catalyst support materials obtainable by the methods, and catalysts prepared from such supports.Type: GrantFiled: January 29, 2013Date of Patent: May 23, 2017Assignee: Velocys Technologies LimitedInventors: Francis Daly, Laura Richard, Sreekala Rugmini
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Patent number: 9359271Abstract: The disclosed invention relates to a process for conducting a Fischer-Tropsch reaction, comprising flowing a reactant mixture comprising fresh synthesis gas and tail gas in a microchannel reactor in contact with a catalyst to form at least one hydrocarbon product, the catalyst being derived from a catalyst precursor comprising cobalt and a surface modified catalyst support.Type: GrantFiled: April 7, 2015Date of Patent: June 7, 2016Assignee: Velocys, Inc.Inventors: Stephen Claude LeViness, Francis Daly, Laura Amanda Richard, Sreekala Rugmini
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Publication number: 20150288000Abstract: A new electroless plating approach to generate a porous metallic coating is described in which a metal is electrolessly deposited on a surface. Microparticles in the metal are removed to leave pores in the metal coating. Another method of forming electroless coatings is described in which a blocking ligand is attached to the surface, followed by a second coating step. The invention includes coatings and coated apparatus formed by methods of the invention. The invention also includes catalyst structures comprising a dense substrate and a porous metal adhered to the dense substrate, which is further characterized by one or more of the specified features.Type: ApplicationFiled: June 17, 2015Publication date: October 8, 2015Inventors: Richard Q. Long, Francis Daly, Haibiao Chen, Terry J. Mazanec
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Publication number: 20150210606Abstract: The disclosed invention relates to a process for conducting a Fischer-Tropsch reaction, comprising flowing a reactant mixture comprising fresh synthesis gas and tail gas in a microchannel reactor in contact with a catalyst to form at least one hydrocarbon product, the catalyst being derived from a catalyst precursor comprising cobalt and a surface modified catalyst support.Type: ApplicationFiled: April 7, 2015Publication date: July 30, 2015Inventors: Stephen Claude LeViness, Francis Daly, Laura Amanda Richard, Sreekala Rugmini
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Patent number: 9006298Abstract: The disclosed invention relates to a process for conducting a Fischer-Tropsch reaction, comprising flowing a reactant mixture comprising fresh synthesis gas and tail gas in a microchannel reactor in contact with a catalyst to form at least one hydrocarbon product, the catalyst being derived from a catalyst precursor comprising cobalt and a surface modified catalyst support.Type: GrantFiled: March 14, 2013Date of Patent: April 14, 2015Assignee: Velocys, Inc.Inventors: Stephen Claude LeViness, Francis Daly, Laura Richard, Sreekala Rugmini
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Publication number: 20150018439Abstract: A method for the preparation of a modified catalyst support comprising: (a) treating a bare catalyst support material with an aqueous solution or dispersion of one or more titanium metal sources and one or more carboxylic acids; and (b) drying the treated support, and (c) optionally calcining the treated support. Also provided are catalyst support materials obtainable by the methods, and catalysts prepared from such supports.Type: ApplicationFiled: January 29, 2013Publication date: January 15, 2015Inventors: Francis Daly, Laura Richard, Sreekala Rugmini
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Patent number: 8900087Abstract: An inline automatic bicycle transmission, containing a planetary gear train, wherein gear selection is done by operation of a centrifugal governor. As the speed of the bicycle increases the transmission will automatically shift into a high gear ratio and the reverse occurs as the bicycle speed decreases.Type: GrantFiled: March 15, 2013Date of Patent: December 2, 2014Inventor: Francis Daly Ward
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Publication number: 20140274545Abstract: An inline automatic bicycle transmission, containing a planetary gear train, wherein gear selection is done by operation of a centrifugal governor. As the speed of the bicycle increases the transmission will automatically shift into a high gear ratio and the reverse occurs as the bicycle speed decreases.Type: ApplicationFiled: March 15, 2013Publication date: September 18, 2014Inventor: Francis Daly Ward
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Publication number: 20140045954Abstract: The disclosed invention relates to a process for conducting a Fischer-Tropsch reaction, comprising flowing a reactant mixture comprising fresh synthesis gas and tail gas in a microchannel reactor in contact with a catalyst to form at least one hydrocarbon product, the catalyst being derived from a catalyst precursor comprising cobalt and a surface modified catalyst support.Type: ApplicationFiled: March 14, 2013Publication date: February 13, 2014Applicant: VELOCYS, INC.Inventors: Stephen Claude LeViness, Francis Daly, Laura Richard, Sreekala Rugmini
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Publication number: 20090075156Abstract: A new electroless plating approach to generate a porous metallic coating is described in which a metal is electrolessly deposited on a surface. Microparticles in the metal are removed to leave pores in the metal coating. Another method of forming electroless coatings is described in which a blocking ligand is attached to the surface, followed by a second coating step. The invention includes coatings and coated apparatus formed by methods of the invention. The invention also includes catalyst structures comprising a dense substrate and a porous metal adhered to the dense substrate, which is further characterized by one or more of the specified features.Type: ApplicationFiled: September 15, 2008Publication date: March 19, 2009Applicant: Velocys Inc.Inventors: Richard Q. Long, Francis Daly, Haibiao Chen, Terry J. Mazanec
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Publication number: 20070225532Abstract: The disclosed invention relates to a process for converting ethylbenzene to styrene, comprising: flowing a feed composition comprising ethylbenzene in at least one process microchannel in contact with at least one catalyst to dehydrogenate the ethylbenzene and form a product comprising styrene; exchanging heat between the process microchannel and at least one heat exchange channel in thermal contact with the process microchannel; and removing product from the process microchannel. Also disclosed is an apparatus comprising a process microchannel, a heat exchange channel, and a heat transfer wall positioned between the process microchannel and heat exchange channel wherein the heat transfer wall comprises a thermal resistance layer.Type: ApplicationFiled: March 23, 2007Publication date: September 27, 2007Inventors: Anna Tonkovich, Kai Paul Jarosch, Bin Yang, Francis Daly, Thomas Hickey, Jeffrey Marco
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Publication number: 20070154360Abstract: The invention describes microchannel apparatus and catalysts that contain a layer of a platinum aluminide. The invention includes chemical processes conducted through apparatus described in the specification.Type: ApplicationFiled: October 13, 2006Publication date: July 5, 2007Applicant: VELOCYS INC.Inventors: Francis Daly, Richard Long, Barry Yang, Terry Mazanec, Frederick Pettit
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Publication number: 20060251552Abstract: The disclosed invention relates to a process for converting a reactant composition comprising H2 and CO to a product comprising at least one aliphatic hydrocarbon having at least about 5 carbon atoms, the process comprising: flowing the reactant composition through a microchannel reactor in contact with a Fischer-Tropsch catalyst to convert the reactant composition to the product, the microchannel reactor comprising a plurality of process microchannels containing the catalyst; transferring heat from the process microchannels to a heat exchanger; and removing the product from the microchannel reactor; the process producing at least about 0.5 gram of aliphatic hydrocarbon having at least about 5 carbon atoms per gram of catalyst per hour; the selectivity to methane in the product being less than about 25%. The disclosed invention also relates to a supported catalyst comprising Co, and a microchannel reactor comprising at least one process microchannel and at least one adjacent heat exchange zone.Type: ApplicationFiled: July 11, 2006Publication date: November 9, 2006Inventors: Yong Wang, Anna Tonkovich, Terry Mazanec, Francis Daly, Dave VanderWiel, Jianli Hu, Chunshe Cao, Charles Kibby, Xiaohong Li, Michael Briscoe, Nathan Gano, Ya-Huei Chin
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Publication number: 20060116528Abstract: The invention provides methods, apparatus and chemical systems for making vinyl acetate from ethylene, oxygen, and acetic acid.Type: ApplicationFiled: October 20, 2005Publication date: June 1, 2006Inventors: Terry Mazanec, Victor Johnston, Michael Huckman, Sean Fitzgerald, James Foster, Daniel Lindley, Anna Tonkovich, Francis Daly, Leslie Wade, Tony Hammock, Thomas Yuschak, Bin Yang, Kai Jarosch
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Publication number: 20060102519Abstract: The disclosed invention relates to a process for conducting a multiphase reaction in a microchannel. The process comprises: forming a multiphase reaction mixture comprising a first reactant and a second reactant; the first reactant comprising at least one liquid; the second reactant comprising at least one gas, at least one liquid, or a combination of at least one gas and at least one liquid; the first reactant forming a continuous phase in the multiphase reaction mixture; the second reactant forming gas bubbles and/or liquid droplets dispersed in the continuous phase; and reacting the first reactant with the second reactant in a process microchannel in the presence of at least one catalyst to form at least one product.Type: ApplicationFiled: November 16, 2005Publication date: May 18, 2006Inventors: Anna Tonkovich, David Hesse, Paul Neagle, Micheal Lamont, Francis Daly, Kai Paul Jarosch, Richard Stevenson, Laura Silva
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Publication number: 20060083672Abstract: The invention provides methods of combusting a fuel in a reactor that includes at least 3 zones each of which contains a solid catalyst. A method of making a thermally-stable alumina support from fumed alumina is also described.Type: ApplicationFiled: October 15, 2004Publication date: April 20, 2006Inventors: Francis Daly, Junko Watson, Yong Wang, Jianli Hu, Chunshe Cao, Richard Long, Rachid Taha