Abstract: The present disclosure is concerned with a computer implemented method for segmenting an image including a plurality of pixels. The method includes: processing the image to generate a first trimap and a second trimap, each trimap segmenting each pixel of the image into either a foreground region, a background region or an unknown region; performing a reconciliation algorithm on the first trimap and the second trimap to yield a merged trimap; processing the merged trimap and image to yield an alpha matte, the alpha matte including an alpha value for at least each pixel in the unknown region; and applying the alpha matte to the image to remove the background region therefrom.

Abstract: The invention provides methods for treating patients which methods comprise methods for predicting responses of cells, such as tumor cells, to treatment with therapeutic agents. These methods involve measuring, in a sample of the cells, levels of one or more components of a cellular network and then computing a Network Activation State (NAS) or a Network Inhibition State (NIS) for the cells using a computational model of the cellular network. The response of the cells to treatment is then predicted based on the NAS or NIS value that has been computed. The invention also comprises predictive methods for cellular responsiveness in which computation of a NAS or NIS value for the cells (e.g., tumor cells) is combined with use of a statistical classification algorithm. Biomarkers for predicting responsiveness to treatment with a therapeutic agent that targets a component within the ErbB signaling pathway are also provided.

Abstract: The invention provides methods for treating patients which methods comprise methods for predicting responses of cells, such as tumor cells, to treatment with therapeutic agents. These methods involve measuring, in a sample of the cells, levels of one or more components of a cellular network and then computing a Network Activation State (NAS) or a Network Inhibition State (NIS) for the cells using a computational model of the cellular network. The response of the cells to treatment is then predicted based on the NAS or NIS value that has been computed. The invention also comprises predictive methods for cellular responsiveness in which computation of a NAS or NIS value for the cells (e.g., tumor cells) is combined with use of a statistical classification algorithm. Biomarkers for predicting responsiveness to treatment with a therapeutic agent that targets a component within the ErbB signaling pathway are also provided.

Abstract: The invention provides methods for treating patients which methods comprise methods for predicting responses of cells, such as tumor cells, to treatment with therapeutic agents. These methods involve measuring, in a sample of the cells, levels of one or more components of a cellular network and then computing a Network Activation State (NAS) or a Network Inhibition State (NIS) for the cells using a computational model of the cellular network. The response of the cells to treatment is then predicted124 based on the NAS or NIS value that has been computed. The invention also comprises predictive methods for cellular responsiveness in which computation of a NAS or NIS value for the cells (e.g., tumor cells) is combined with use of a statistical classification algorithm. Biomarkers for predicting responsiveness to treatment with a therapeutic agent that targets a component within the ErbB signaling pathway are also provided.

Abstract: There is provided an aqueous liquid domestic composition comprising (i) one or more active component selected from the group consisting of (A) 3% to 50% by weight, based on the total solids weight of said domestic composition, one or more softening agent, (B) 2% to 90% by weight, based on the total solids weight of said domestic composition, one or more anionic surfactant, and (C) a mixture consisting of (I) 1% to 25% by weight, based on the total solids weight of said domestic composition, one or more softening agent, and (II) 5% to 75% by weight, based on the total solids weight of said domestic composition, one or more anionic surfactant, and (D) 0.1% to 30% by weight, based on the total solids weight of said domestic composition, one or more amphoteric compound; and (ii) one or more cationic polymer latex comprising (I) 0.5% to 6% by weight, based on the dry weight of said polymer, one or more cationic monomer, (II) 30% to 99.

Abstract: The invention provides methods for treating patients which methods comprise methods for predicting responses of cells, such as tumor cells, to treatment with therapeutic agents. These methods involve measuring, in a sample of the cells, levels of one or more components of a cellular network and then computing a Network Activation State (NAS) or a Network Inhibition State (NIS) for the cells using a computational model of the cellular network. The response of the cells to treatment is then predicted based on the NAS or NIS value that has been computed. The invention also comprises predictive methods for cellular responsiveness in which computation of a NAS or NIS value for the cells (e.g., tumor cells) is combined with use of a statistical classification algorithm. Biomarkers for predicting responsiveness to treatment with a therapeutic agent that targets a component within the ErbB signaling pathway are also provided.

Abstract: The invention provides methods for treating patients which methods comprise methods for predicting responses of cells, such as tumor cells, to treatment with therapeutic agents. These methods involve measuring, in a sample of the cells, levels of one or more components of a cellular network and then computing a Network Activation State (NAS) or a Network Inhibition State (NIS) for the cells using a computational model of the cellular network. The response of the cells to treatment is then predicted based on the NAS or NIS value that has been computed. The invention also comprises predictive methods for cellular responsiveness in which computation of a NAS or NIS value for the cells (e.g., tumor cells) is combined with use of a statistical classification algorithm. Biomarkers for predicting responsiveness to treatment with a therapeutic agent that targets a component within the ErbB signaling pathway are also provided.

Abstract: There is provided an aqueous liquid domestic composition comprising (i) one or more active component selected from the group consisting of (A) 3% to 50% by weight, based on the total solids weight of said domestic composition, one or more softening agent, (B) 2% to 90% by weight, based on the total solids weight of said domestic composition, one or more anionic surfactant, and (C) a mixture consisting of (I) 1% to 25% by weight, based on the total solids weight of said domestic composition, one or more softening agent, and (II) 5% to 75% by weight, based on the total solids weight of said domestic composition, one or more anionic surfactant, and (D) 0.1% to 30% by weight, based on the total solids weight of said domestic composition, one or more amphoteric compound; and(ii) one or more cationic polymer latex comprising (I) 0.5% to 6% by weight, based on the dry weight of said polymer, one or more cationic monomer, (II) 30% to 99.

Abstract: An aqueous composition having a pH of at least 10, and comprising from 0.1% to 5% of at least one crosslinked copolymer comprising from 2.5% to 65% (meth)acrylic acid residues, from 10% to 80% C2-C4 alkyl (meth)acrylate residues, from 2% to 25% lipophilically modified (meth)acrylate residues and residues of a crosslinker that has no ester or amide functionality.

Abstract: Frames and attachments thereto and methods of use thereof for the support and/or releasable securing of cargo and/or cargo containers upon and/or to cargo containers and/or cargo container transports and/or lifting devices. Linking frame (10) may be used upon and/or beneath containers that possess insufficient mutually corresponding mounting-points to otherwise enable them to be vertically stacked and secured together. Parallel longitudinal beams (11) are joined by shorter lateral beams (12). Attached directly or indirectly, protruding outward the outer side surfaces of said framework, are connectors (13) able to correspond upwardly and/or downwardly with various mounting-point layouts as provided upon the surfaces of cargo transport equipment.

Abstract: Novel carboxamide derivatives having CNS activity, processes for their preparation and their use as medicaments.

Abstract: A system and method for automatically determining equipment control sets and presenting the information to a database for generation of a user interface is disclosed. A control network adapter (“CNA”) is designed to automatically determine the control code sets for almost any controllable product by executing an Automatic Configuration Routine (“ACR”) and then presents this information to a user interface, for example to a graphic user interface or to a network, for example, a transmission control protocol/Internet protocol (TCP/IP) network through the use of an automatically generated web page. The CNA has the ability to automatically determine what kind of device it is controlling and what are the appropriate control codes to effectuate control of the device, thus eliminating the need for cumbersome, expensive manual programming of the controller with device-specific codes.

Abstract: Frames and attachments thereto and methods of use thereof for the support and/or releasable securing of cargo and/or cargo containers upon and/or to cargo containers and/or cargo container transports and/or lifting devices. Linking frame (10) may be used upon and/or beneath containers that possess insufficient mutually corresponding mounting-points to otherwise enable them to be vertically stacked and secured together. Parallel longitudinal beams (11) are joined by shorter lateral beams (12). Attached directly or indirectly, protruding outward the outer side surfaces of said framework, are connectors (13) able to correspond upwardly and/or downwardly with various mounting-point layouts as provided upon the surfaces of cargo transport equipment.

Abstract: The invention concerns an illuminating spotlight emitting a narrow beam. The spotlight has a highly concentrated light source and a concave reflector for emitting an illuminating beam in a specific direction, along an emitting axis. A converging lens is interposed between the source and the reflector and in a plane passing through a conical segment. The source is bordered laterally on the reflector side with a sector of the converging lens providing a virtual image of the source located beyond the emitting axis, on the side opposite that of the lens. The virtual image of the light source is formed at the focus of the conical segment locally defining the reflector.

Abstract: A compound of formula (I) or a pharmaceutically acceptable salt thereof: 1

Abstract: Novel sulphonamide derivatives having CNS activity, processes for their preparation and their use as medicaments are disclosed.

Abstract: Aqueous compositions having enhanced thickening properties containing lipophilically-modified copolymer thickeners and one or more hydrophilic surfactants are disclosed. In particular, aqueous compositions containing (i) lipophilically-modified copolymers containing at least 5% of selected lipophilically-modified components and (ii) surfactants having an HLB value of greater than 15 are useful for the thickening of a range of personal, domestic and industrial products.

Abstract: Compounds of formula (I) and pharmaceutically acceptable salts thereof, and the use of a compound of formula (I) or a pharmaceutically acceptable salt thereof:

Abstract: Novel sulphonamide derivatives having CNS activity, processes for their preparation and their use as medicaments.

Abstract: Aqueous compositions having enhanced thickening properties containing lipophilically-modified copolymer thickeners and one or more hydrophilic surfactants are disclosed. In particular, aqueous compositions containing (i) lipophilically-modified copolymers containing at least 5% of selected lipophilically-modified components and (ii) surfactants having an HLB value of greater than 15 are useful for the thickening of a range of personal, domestic and industrial products.