Abstract: An improved system and method of determining a low water and/or water-out condition in a humidifier chamber of a respiratory or surgical humidifier system can use a specific frequency band to detect changes in a temperature of a heater plate. The temperature changes can correlate to the specific heat capacity value of the humidifier chamber. The low water and/or water-out detection process can be performed without having to determine the gases flow rate and/or can be run continuously. A heater plate assembly of the system can include a compliant insulation sheet to improve thermal coupling between the heating element and the top heating plate of the heater plate assembly, thereby improving the low water and/or water-out detection process.

Abstract: Systems and methods for application identification in accordance with embodiments of the invention are disclosed. In one embodiment, a user device includes a processor and memory configured to store an application, a session manager, an application identifier, and at least one shared library, and the processor is configured by the session manager to communicate the application identifier and the application identifier data to an authentication server and permit the execution of the application in response to authentication of the application by the authentication server.

Abstract: An implantable growing rod assembly adapted to be secured along a length of a spine for treating deformities of the spine. The assembly includes a housing, a fixed rod extending along a longitudinal axis away from the housing, and an expansion rod extendible from the housing along the longitudinal axis. A driver assembly is fixed to the housing and adapted to translate the expansion rod along the longitudinal axis.

Abstract: An assembly set for assembling an external rearview system for a motor vehicle is provided. The external rearview system when assembled may include a base assembly provided for arrangement on the motor vehicle, and a head assembly attached to the base assembly. The assembly set may include (i) a first head assembly comprising, a first rearview device comprising at least one reflective element in form of a mirror glass, (ii) a second head assembly comprising, a second rearview device comprising at least one reflective element in form of an at least partly translucent mirror glass, and at least one first camera unit being configured to obtain a rearview image through the reflective element, and (iii) a third head assembly with at least one component of a camera monitor system. The head assembly may be configured to be detachable and is selected to be the first, second or third head assembly, with the first, second and third head assembly being exchangeable with each other.

Abstract: A method/system monitors and controls operational aspects of devices in a space, for example a living, office or other human-occupied space or storage space, in a building, such as turning lights on/off, raising/lowering blinds, maintaining or changing temperature, and other operational aspects. Sensors monitor energy usage of the devices in the space, and a controller/engine compares the monitored energy usage with reference energy usage to validate whether the devices are performing as expected. A temperate set-versus-anomaly detection technique may use temperature set point adjustments by a user (during a timeframe) to determine whether an anomaly exists that requires changes in the central plant of the building.

Abstract: Aspects of the present disclosure involve systems for providing multiple egress routes from a telecommunications network for a client of the network. In general, the system provides for a client of the network to receive intended packets of information through multiple connections to the network such that load balancing and failover services for traffic to the customer are provided. The process and system allow for telecommunications network to utilize a common next-hop value of announced border gateway protocol (BGP) routes to advertise multiple routes to reach a destination customer network or address. By utilizing a common next-hop value in the announced BGP information, the devices of the network may load balance communication packets to the destination customer or address among the multiple egress locations from the network, as well as providing fast failover to alternate routes when a failure at the network or customer occurs.

Abstract: An implantable growing rod assembly adapted to be secured along a length of a spine for treating deformities of the spine. The assembly includes a housing, a fixed rod extending along a longitudinal axis away from the housing, and an expansion rod extendible from the housing along the longitudinal axis. A driver assembly is fixed to the housing and adapted to translate the expansion rod along the longitudinal axis.

Abstract: The present invention is directed to a pharmaceutical composition comprising the compound suvorexant, or a pharmaceutically acceptable salt thereof, a concentration-enhancing polymer, and optionally a pharmaceutically acceptable surfactant.

Abstract: A system enables universal remote media control across multiple platforms, devices, and users. A protocol allows a cast controller to have access to media operations and a state(s) associated with media content. The system receives commands from a cast controller, provides the commands to a media player, loads new media content into the media player, based on the commands, and receives state notifications from the media player. Another cast controller can receive the state notifications from the media player and control the media player based on the media operations and state(s) associated with media content.

Abstract: The present disclosure is concerned with a computer implemented method for segmenting an image including a plurality of pixels. The method includes: processing the image to generate a first trimap and a second trimap, each trimap segmenting each pixel of the image into either a foreground region, a background region or an unknown region; performing a reconciliation algorithm on the first trimap and the second trimap to yield a merged trimap; processing the merged trimap and image to yield an alpha matte, the alpha matte including an alpha value for at least each pixel in the unknown region; and applying the alpha matte to the image to remove the background region therefrom.

Abstract: The invention provides methods for treating patients which methods comprise methods for predicting responses of cells, such as tumor cells, to treatment with therapeutic agents. These methods involve measuring, in a sample of the cells, levels of one or more components of a cellular network and then computing a Network Activation State (NAS) or a Network Inhibition State (NIS) for the cells using a computational model of the cellular network. The response of the cells to treatment is then predicted based on the NAS or NIS value that has been computed. The invention also comprises predictive methods for cellular responsiveness in which computation of a NAS or NIS value for the cells (e.g., tumor cells) is combined with use of a statistical classification algorithm. Biomarkers for predicting responsiveness to treatment with a therapeutic agent that targets a component within the ErbB signaling pathway are also provided.

Abstract: The invention provides methods for treating patients which methods comprise methods for predicting responses of cells, such as tumor cells, to treatment with therapeutic agents. These methods involve measuring, in a sample of the cells, levels of one or more components of a cellular network and then computing a Network Activation State (NAS) or a Network Inhibition State (NIS) for the cells using a computational model of the cellular network. The response of the cells to treatment is then predicted based on the NAS or NIS value that has been computed. The invention also comprises predictive methods for cellular responsiveness in which computation of a NAS or NIS value for the cells (e.g., tumor cells) is combined with use of a statistical classification algorithm. Biomarkers for predicting responsiveness to treatment with a therapeutic agent that targets a component within the ErbB signaling pathway are also provided.

Abstract: The invention provides methods for treating patients which methods comprise methods for predicting responses of cells, such as tumor cells, to treatment with therapeutic agents. These methods involve measuring, in a sample of the cells, levels of one or more components of a cellular network and then computing a Network Activation State (NAS) or a Network Inhibition State (NIS) for the cells using a computational model of the cellular network. The response of the cells to treatment is then predicted124 based on the NAS or NIS value that has been computed. The invention also comprises predictive methods for cellular responsiveness in which computation of a NAS or NIS value for the cells (e.g., tumor cells) is combined with use of a statistical classification algorithm. Biomarkers for predicting responsiveness to treatment with a therapeutic agent that targets a component within the ErbB signaling pathway are also provided.

Abstract: There is provided an aqueous liquid domestic composition comprising (i) one or more active component selected from the group consisting of (A) 3% to 50% by weight, based on the total solids weight of said domestic composition, one or more softening agent, (B) 2% to 90% by weight, based on the total solids weight of said domestic composition, one or more anionic surfactant, and (C) a mixture consisting of (I) 1% to 25% by weight, based on the total solids weight of said domestic composition, one or more softening agent, and (II) 5% to 75% by weight, based on the total solids weight of said domestic composition, one or more anionic surfactant, and (D) 0.1% to 30% by weight, based on the total solids weight of said domestic composition, one or more amphoteric compound; and (ii) one or more cationic polymer latex comprising (I) 0.5% to 6% by weight, based on the dry weight of said polymer, one or more cationic monomer, (II) 30% to 99.

Abstract: The invention provides methods for treating patients which methods comprise methods for predicting responses of cells, such as tumor cells, to treatment with therapeutic agents. These methods involve measuring, in a sample of the cells, levels of one or more components of a cellular network and then computing a Network Activation State (NAS) or a Network Inhibition State (NIS) for the cells using a computational model of the cellular network. The response of the cells to treatment is then predicted based on the NAS or NIS value that has been computed. The invention also comprises predictive methods for cellular responsiveness in which computation of a NAS or NIS value for the cells (e.g., tumor cells) is combined with use of a statistical classification algorithm. Biomarkers for predicting responsiveness to treatment with a therapeutic agent that targets a component within the ErbB signaling pathway are also provided.

Abstract: The invention provides methods for treating patients which methods comprise methods for predicting responses of cells, such as tumor cells, to treatment with therapeutic agents. These methods involve measuring, in a sample of the cells, levels of one or more components of a cellular network and then computing a Network Activation State (NAS) or a Network Inhibition State (NIS) for the cells using a computational model of the cellular network. The response of the cells to treatment is then predicted based on the NAS or NIS value that has been computed. The invention also comprises predictive methods for cellular responsiveness in which computation of a NAS or NIS value for the cells (e.g., tumor cells) is combined with use of a statistical classification algorithm. Biomarkers for predicting responsiveness to treatment with a therapeutic agent that targets a component within the ErbB signaling pathway are also provided.

Abstract: There is provided an aqueous liquid domestic composition comprising (i) one or more active component selected from the group consisting of (A) 3% to 50% by weight, based on the total solids weight of said domestic composition, one or more softening agent, (B) 2% to 90% by weight, based on the total solids weight of said domestic composition, one or more anionic surfactant, and (C) a mixture consisting of (I) 1% to 25% by weight, based on the total solids weight of said domestic composition, one or more softening agent, and (II) 5% to 75% by weight, based on the total solids weight of said domestic composition, one or more anionic surfactant, and (D) 0.1% to 30% by weight, based on the total solids weight of said domestic composition, one or more amphoteric compound; and(ii) one or more cationic polymer latex comprising (I) 0.5% to 6% by weight, based on the dry weight of said polymer, one or more cationic monomer, (II) 30% to 99.

Abstract: An aqueous composition having a pH of at least 10, and comprising from 0.1% to 5% of at least one crosslinked copolymer comprising from 2.5% to 65% (meth)acrylic acid residues, from 10% to 80% C2-C4 alkyl (meth)acrylate residues, from 2% to 25% lipophilically modified (meth)acrylate residues and residues of a crosslinker that has no ester or amide functionality.

Abstract: Frames and attachments thereto and methods of use thereof for the support and/or releasable securing of cargo and/or cargo containers upon and/or to cargo containers and/or cargo container transports and/or lifting devices. Linking frame (10) may be used upon and/or beneath containers that possess insufficient mutually corresponding mounting-points to otherwise enable them to be vertically stacked and secured together. Parallel longitudinal beams (11) are joined by shorter lateral beams (12). Attached directly or indirectly, protruding outward the outer side surfaces of said framework, are connectors (13) able to correspond upwardly and/or downwardly with various mounting-point layouts as provided upon the surfaces of cargo transport equipment.

Abstract: Novel carboxamide derivatives having CNS activity, processes for their preparation and their use as medicaments.