Patents by Inventor Francis Durst

Francis Durst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recording of DNA sequences to enable them to be expressed in yeasts, and the transformed yeasts obtained
    Patent number: 6787337
    Abstract: The present invention relates to a recombinant non-yeast DNA, which encodes a protein of interest, wherein an unmodified DNA corresponding to the recombinant non-yeast DNA contains a region having a high content of codons that are poorly suited to yeasts, wherein a number of the codons that are poorly suited to yeasts are replaced in said region of the recombinant non-yeast DNA with synonymous codons coding for the same amino acid that are well-suited to yeasts, and wherein the number of replaced codons is sufficient to permit expression in yeasts. The present invention also relates to DNA sequences which originate from dicotyledonous or monocotyledonous plants, and in particular plants of the graminae family which are selected from among wheat, barley, oats, rice, maize, sorghum and cane sugar, as well as to vectors and transformed yeasts which contain the DNA sequences of the invention.
    Type: Grant
    Filed: November 15, 2000
    Date of Patent: September 7, 2004
    Assignee: Aventis CropScience S.A.
    Inventors: Yannick Batard, Francis Durst, Michel Schalk, Daniele Werck-Reichhart
  • PURIFIED CYTOCHROME P450 POLYPEPTIDE CYP76B1 FROM HELIANTHUS TUBEROSUS AND ITS APPLICATIONS AS BIOCATALYST IN PARTICULAR FOR THE DEGRADATION OF ENVIRONMENTAL POLLUTANTS AND FOR ALTERING THE RESISTANCE OF PLANTS SENSITIVE TO PHENYLUREA FAMILY OF HERBICIDES
    Patent number: 6376753
    Abstract: The present invention relates to the gene CYP76B1 of a cytochrome P450 which has been isolated from Helianthus tuberosus tuber. The expression of this gene in yeast has shown that it encoded an enzyme very actively catalysing the O-dealkylation of various exogenous molecules with a high efficiency, such as phenylureas. The expression of CYP76B1 is strongly induced in plants brought into contact with certain exogenous metals or organic compounds. This induction may be exploited for the detection of environmental pollutants. CYP76B1 can be also used to alter the resistance of plants sensitive to this family of herbicides and for soil and groundwater bioremedation.
    Type: Grant
    Filed: July 30, 1998
    Date of Patent: April 23, 2002
    Assignee: Centre National de la Recherche Scientifique
    Inventors: Yannick Batard, Tiburce Robineau, Francis Durst, Daniele Werck-Reichhart, Luc Didierjean
  • Recoding of DNA sequences permitting expression in yeast and obtained transformed yeast
    Patent number: 6180363
    Abstract: The present invention relates to a DNA sequence which encodes a protein of interest which contains regions having a high content of codons which are poorly suited to yeasts, characterized in that a sufficient number of codons which are poorly suited to yeasts is replaced with corresponding codons which are well-suited to yeasts in the said regions having a high content of codons which are poorly suited to yeasts. The present invention relates, more specifically, to DNA sequences which originate from dicotyledonous or monocotyledonous plants, in particular plants of the graminae family which are selected, in particular, from among wheat, barley, oats, rice, maize, sorghum and cane sugar. The present invention also relates to transformed yeasts which contain a DNA sequence according to the invention.
    Type: Grant
    Filed: September 23, 1998
    Date of Patent: January 30, 2001
    Assignee: Rhone-Poulenc Agro
    Inventors: Yannick Batard, Francis Durst, Michel Schalk, Daniele Werck-Reichhart