Patents by Inventor Francis G. Blankenberg

Francis G. Blankenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Molecular vibrational spectroscopic markers for detection of cancer
    Patent number: 11774451
    Abstract: Methods of detecting diagnostic biomarkers on cancer-derived extracellular vesicles such as exosomes by mid-infrared spectroscopy are provided. In particular, methods of detecting ovarian cancer by spectral fingerprint analysis of molecular vibrational spectroscopic markers on individual or subpopulations of extracellular vesicles are disclosed.
    Type: Grant
    Filed: November 11, 2020
    Date of Patent: October 3, 2023
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Derek Holman, Francis G. Blankenberg
  • USE OF ANNEXIN V AS A METHOD TO BLOCK TUMOR INDUCED IMMUNOSUPPRESSION OF THE INNATE IMMUNE RESPONSE
    Publication number: 20220160829
    Abstract: Methods are provided for treating a subject with cancer, with a therapeutic dose of annexin V to the subject.
    Type: Application
    Filed: January 12, 2022
    Publication date: May 26, 2022
    Inventor: Francis G. Blankenberg
  • Use of annexin v as a method to block tumor induced immunosuppression of the innate immune response
    Patent number: 11253568
    Abstract: Methods are provided for treating a subject with cancer, with a therapeutic dose of annexin V to the subject.
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: February 22, 2022
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventor: Francis G. Blankenberg
  • MOLECULAR VIBRATIONAL SPECTROSCOPIC MARKERS FOR DETECTION OF CANCER
    Publication number: 20210156862
    Abstract: Methods of detecting diagnostic biomarkers on cancer-derived extracellular vesicles such as exosomes by mid-infrared spectroscopy are provided. In particular, methods of detecting ovarian cancer by spectral fingerprint analysis of molecular vibrational spectroscopic markers on individual or subpopulations of extracellular vesicles are disclosed.
    Type: Application
    Filed: November 11, 2020
    Publication date: May 27, 2021
    Inventors: Derek Holman, Francis G. Blankenberg
  • USE OF ANNEXIN V AS A METHOD TO BLOCK TUMOR INDUCED IMMUNOSUPPRESSION OF THE INNATE IMMUNE RESPONSE
    Publication number: 20170202914
    Abstract: Methods are provided for treating a subject with cancer, with a therapeutic dose of annexin V to the subject.
    Type: Application
    Filed: October 2, 2015
    Publication date: July 20, 2017
    Inventor: Francis G. Blankenberg
  • COMPOSITIONS FOR IMAGING PAIN AND STRESS IN VIVO
    Publication number: 20110097267
    Abstract: Briefly described, embodiments of the present disclosure relate to methods and compositions for imaging pain and/or stress in a subject and methods and compositions for treating associated conditions. In particular, the present disclosure relates to the use of labeled compounds to provide objective diagnosis of pain and/or stress, for imaging regions associated with pain and/or stress, and for treating pain in a subject.
    Type: Application
    Filed: December 2, 2010
    Publication date: April 28, 2011
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Sandip Biswal, Francis G. Blankenberg
  • Compositions and methods for imaging pain and stress in vivo
    Patent number: 7871623
    Abstract: Briefly described, embodiments of the present disclosure relate to methods and compositions for imaging pain and/or stress in a subject and methods and compositions for treating associated conditions. In particular, the present disclosure relates to the use of labeled compounds to provide objective diagnosis of pain and/or stress, for imaging regions associated with pain and/or stress, and for treating pain in a subject.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: January 18, 2011
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Sandip Biswal, Francis G. Blankenberg
  • Method of imaging cell death in vivo
    Patent number: 7666389
    Abstract: A method of imaging apoptosis in vivo, using radiolabeled annexin, is described.
    Type: Grant
    Filed: November 15, 2007
    Date of Patent: February 23, 2010
    Assignees: The Board of Trustees of the Leland Stanford Junior University, University of Washington
    Inventors: Francis G. Blankenberg, Peter D. Katsikis, H. William Strauss, Jonathan F. Tait
  • Method of imaging cell death in vivo
    Publication number: 20080138279
    Abstract: A method of imaging apoptosis in vivo, using radiolabeled annexin, is described.
    Type: Application
    Filed: November 15, 2007
    Publication date: June 12, 2008
    Applicants: The Board of Trustees of the Leland Stanford Junior University, University of Washington
    Inventors: Francis G. Blankenberg, H. William Strauss, Jonathan F. Tait, Peter D. Katsikis
  • Method of imaging cell death in vivo
    Patent number: 7357915
    Abstract: A method of imaging apoptosis in vivo, using radiolabeled annexin, is described.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: April 15, 2008
    Assignees: The Board of Trustees of the Leland Stanford Junior University, University of Washington
    Inventors: Francis G. Blankenberg, H. W. Strauss, Jonathan F. Tait, Peter D. Katsikis
  • Method of imaging cell death in vivo
    Publication number: 20040170603
    Abstract: A method of imaging apoptosis in vivo, using radiolabeled annexin, is described. Methods for tumor radiotherapy are also provided.
    Type: Application
    Filed: March 5, 2004
    Publication date: September 2, 2004
    Applicants: The Board of Trustees of the Leland Stanford Junior University, Theseus Imaging Corporation
    Inventors: H. William Strauss, Francis G. Blankenberg, Allan M. Green, Neil Steinmetz
  • Method of imaging cell death in vivo
    Patent number: 6726895
    Abstract: A method of imaging apoptosis in vivo, using radiolabeled annexin, is described. Methods for tumor radiotherapy are also provided.
    Type: Grant
    Filed: April 3, 2002
    Date of Patent: April 27, 2004
    Assignees: Board of Trustees of the Leland Stanford Junior University, Theseus Imaging Corporation
    Inventors: H. William Strauss, Francis G. Blankenberg, Allan M. Green, Neil Steinmetz
  • Intravascular delivery of therapeutic and imaging agents to stressed and apoptotic cells using annexin V as a targeting vector
    Publication number: 20030152513
    Abstract: The present invention relies on the affinity of stressed or apoptotic cells for exogenously administered annexin V to create a multi-functional molecular probe that can be simultaneously used for imaging (localization of unstable plaque within the body) and therapy (treatment of unstable plaque).
    Type: Application
    Filed: September 6, 2002
    Publication date: August 14, 2003
    Applicant: IMETRIX, INC.
    Inventors: Francis G. Blankenberg, Jagat Narula, H. William Strauss, Vartan Ghazarossian
  • Method of imaging cell death in vivo
    Publication number: 20030003047
    Abstract: A method of imaging apoptosis in vivo, using radiolabeled annexin, is described. Methods for tumor radiotherapy are also provided.
    Type: Application
    Filed: April 3, 2002
    Publication date: January 2, 2003
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: H. W. Strauss, Francis G. Blankenberg, Allan M. Green, Neil Steinmetz
  • Method of imaging cell death in vivo
    Patent number: 6197278
    Abstract: A method of imaging apoptosis in vivo, using radiolabeled annexin, is described.
    Type: Grant
    Filed: April 29, 1998
    Date of Patent: March 6, 2001
    Assignees: The Board of Trustees of the Leland Stanford Junior University, University of Washington
    Inventors: Francis G. Blankenberg, H. William Strauss, Jonathan F. Tait, Peter D. Katsikis