Patents by Inventor Francis H. Verhoff

Francis H. Verhoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12257310
    Abstract: Reactive and sorbent materials including a non-encapsulated crosslinked biological material immobilized on a support matrix that includes a polyamine and at least one support material are described. The support material can be an inorganic or organic support material. The reactive and sorbent materials are formed by reacting the biological material with the polyamine, at least one support material, and a crosslinking agent. The materials exhibit enhanced properties generally, are capable of maintaining their reactive and sorbent properties in contact with digestive fluids, and exhibiting their reactive and sorbent properties as they pass throughout an organism's entire digestive system. Reactive and sorbent materials in contact with digestive juices at pH's ranging from about 3 to about 7 have maintained their reactive and sorbent properties for at least 4 hours.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: March 25, 2025
    Inventors: Dominic P. Dinovo, Andrew Dinovo, Matthew F. Smiechowski, Francis H. Verhoff
  • Publication number: 20190078072
    Abstract: The present application discloses immobilized enzymes and immobilized enzyme materials comprising a crosslinked enzyme having a support material which includes a biomass material different than the biomass used to initially derive the enzyme. Optionally, the immobilized enzyme further includes a polymeric material and/or the biomass which was used to initially derive the enzyme. The resulting immobilized enzyme materials may be biodegradable. The present application also discloses methods of making and using the disclosed immobilized enzyme materials.
    Type: Application
    Filed: March 9, 2018
    Publication date: March 14, 2019
    Applicant: Guild Associates, Inc.
    Inventors: Augustine A. DiNovo, Dominic DiNovo, David A. Schofield, Matthew F. Smiechowski, Francis H. Verhoff
  • Publication number: 20180110868
    Abstract: Reactive and sorbent materials including a non-encapsulated crosslinked biological material immobilized on a support matrix that includes a polyamine and at least one support material are described. The support material can be an inorganic or organic support material. The reactive and sorbent materials are formed by reacting the biological material with the polyamine, at least one support material, and a crosslinking agent. The materials exhibit enhanced properties generally, are capable of maintaining their reactive and sorbent properties in contact with digestive fluids, and exhibiting their reactive and sorbent properties as they pass throughout an organism's entire digestive system. Reactive and sorbent materials in contact with digestive juices at pH's ranging from about 3 to about 7 have maintained their reactive and sorbent properties for at least 4 hours.
    Type: Application
    Filed: October 20, 2017
    Publication date: April 26, 2018
    Inventors: Dominic P. DINOVO, Andrew DINOVO, Matthew F. SMIECHOWSKI, Francis H. VERHOFF
  • Patent number: 9944920
    Abstract: The present application discloses immobilized enzymes and immobilized enzyme materials comprising a crosslinked enzyme having a support material which includes a biomass material different than the biomass used to initially derive the enzyme. Optionally, the immobilized enzyme further includes a polymeric material and/or the biomass which was used to initially derive the enzyme. The resulting immobilized enzyme materials may be biodegradable. The present application also discloses methods of making and using the disclosed immobilized enzyme materials.
    Type: Grant
    Filed: November 13, 2012
    Date of Patent: April 17, 2018
    Assignee: Guild Associates, Inc.
    Inventors: Augustine A. DiNovo, Dominic P. DiNovo, David A. Schofield, Matthew F. Smiechowski, Francis H. Verhoff
  • Publication number: 20130316431
    Abstract: The present application discloses immobilized enzymes and immobilized enzyme materials comprising a crosslinked organophosphate-degrading enzyme having a support material which includes a biomass material and/or a polymeric material. The resulting immobilized enzyme materials may be biodegradable. The present application also discloses methods of making and using the disclosed immobilized organophosphate hydrolase enzyme and enzyme materials.
    Type: Application
    Filed: November 13, 2012
    Publication date: November 28, 2013
    Inventors: Augustine A. DiNovo, Dominic P. DiNovo, David A. Schofield, Matthew F. Smiechowski, Francis H. Verhoff
  • Publication number: 20130309746
    Abstract: The present application discloses immobilized enzymes and immobilized enzyme materials comprising a crosslinked enzyme having a support material which includes a biomass material different than the biomass used to initially derive the enzyme. Optionally, the immobilized enzyme further includes a polymeric material and/or the biomass which was used to initially derive the enzyme. The resulting immobilized enzyme materials may be biodegradable. The present application also discloses methods of making and using the disclosed immobilized enzyme materials.
    Type: Application
    Filed: November 13, 2012
    Publication date: November 21, 2013
    Inventors: Augustine A. DiNovo, Dominic P. DiNovo, David A. Schofield, Matthew F. Smiechowski, Francis H. Verhoff
  • Publication number: 20110183382
    Abstract: This invention provides systems and methods for the production of compounds by C. phytofermentans. C. phytofermentans is genetically-engineered for hydrolysis and fermentation of carbonaceous biomass to synthesize compounds of commercial value.
    Type: Application
    Filed: December 15, 2010
    Publication date: July 28, 2011
    Applicant: Qteros, Inc.
    Inventors: Matthias Schmalisch, Chelsea Ju, Francis H. Verhoff, Gregory S. Coil
  • Publication number: 20030000894
    Abstract: A process for treating a liquid comprising subjecting a liquid containing, in solution, citric acid as well as a less desirable component having a similar molecular weight to citric acid, to nanofiltration in a filtration step. From the filtration step, a permeate in which the ratio of the concentration of the citric acid to that of the less desirable component is greater than the ratio of the concentration of the citric acid to that of the less desirable component in the solution, is obtained.
    Type: Application
    Filed: August 21, 2002
    Publication date: January 2, 2003
    Inventors: Francis H. Verhoff, Sanet Grond, Fadl Hendricks, Lakshminarayanan Pattabiraman Raman
  • Patent number: 6114577
    Abstract: Described are preferred processes and apparatuses for thermally desorbing desired chemical products from resins to which they are adsorbed. The processes and apparatuses provide highly efficient use of applied heat throughout resin preheat, desorption and cooling phases.
    Type: Grant
    Filed: October 23, 1996
    Date of Patent: September 5, 2000
    Assignee: Reilly Industries, Inc.
    Inventors: Francis H. Verhoff, Martin Grendze
  • Patent number: 5965028
    Abstract: A process for treating a liquid comprising subjecting a liquid containing, in solution, citric acid as well as a less desirable component having a similar molecular weight to citric acid, to nanofiltration in a filtration step. From the filtration step, a permeate in which the ratio of the concentration of the citric acid to that of the less desirable component is greater than the ratio of the concentration of the citric acid to that of the less desirable component in the solution, is obtained.
    Type: Grant
    Filed: March 4, 1997
    Date of Patent: October 12, 1999
    Assignee: Reilly Industries, Inc.
    Inventors: Francis H. Verhoff, Sanet Grond, Fadl Hendricks, Lakshminarayanan Pattabiraman Raman
  • Patent number: 5869679
    Abstract: Method for synthesizing L-2-oxothiazolidine-4-carboxylate and its acid, L-2-oxothiazolidine-4-carboxylic acid. The present invention involves the separation of phenol from a reaction mixture containing L-2-oxothiazolidine-4-carboxylate and phenol. In the present method a reaction mixture containing phenol, L-2-oxothiazolidine-4-carboxylate, and chloride salt, is contacted with a phenol adsorbing adsorption resin, the adsorption resin comprising a polymer having a polyethylene backbone. The adsorption resin is capable of adsorbing substantially all of the phenol while not adsorbing substantial amounts of the L-2-oxothiazolidine-4-carboxylate from the reaction mixture.
    Type: Grant
    Filed: November 10, 1997
    Date of Patent: February 9, 1999
    Assignee: Transcend Therapeutics, Inc.
    Inventors: Francis H. Verhoff, L. Reade Baxley, Xiaofeng Lin, Gordon J. Rossiter
  • Patent number: 5833757
    Abstract: A process which permits the facile conversion of green bananas to a sugar syrup uses a sequence of steps involving grinding the bananas, heating the bananas, treating the bananas with an alpha amylase to convert the starch granules into lower molecular weight molecules (liquefaction), changing conditions and treating the low molecular weight starch molecules and other substances in the liquefied fluid with the enzymes, amyloglucosidase, pectinase, cellulase, macerase, etc., filtering the resultant fluid to remove the solids, and, if necessary, evaporating the sugar solution to a suitable concentration. Use of elevated pH in each of the enzymatic conversion steps was found to greatly increase the glucose yield.
    Type: Grant
    Filed: December 22, 1995
    Date of Patent: November 10, 1998
    Assignee: U.S. Tech, Inc.
    Inventors: Francis H. Verhoff, Charles S. Blatteis, Cheryl L. Barrett
  • Patent number: 4849357
    Abstract: A enzyme-containing solid composition is prepared by a process comprising removing the solvent from a mixture of a water-soluble enzyme, a water-insoluble metal salt of a fatty acid and an organic solvent.
    Type: Grant
    Filed: October 8, 1986
    Date of Patent: July 18, 1989
    Assignee: Miles Inc.
    Inventors: Koo-Heung Chung, Francis H. Verhoff
  • Patent number: 4609470
    Abstract: An improved method for dewatering aqueous sludge is disclosed comprising flocculating the sludge by the addition of effective amounts of chitosan and an organic dialdehyde such as glutaraldehyde to the sludge, which is also preferably acidified to about pH 6.0.
    Type: Grant
    Filed: July 8, 1985
    Date of Patent: September 2, 1986
    Assignee: Miles Laboratories, Inc.
    Inventors: Koo-Heung Chung, Gary L. Davis, Francis H. Verhoff
  • Patent number: 4234423
    Abstract: The present invention is directed to an improved wet air oxidation system and method for reducing the chemical oxygen demand (COD) of waste water used from scrubbers of coal gasification plants, with this COD reduction being sufficient to effectively eliminate waste water as an environmental pollutant. The improvement of the present invention is provided by heating the air used in the oxidation process to a temperature substantially equal to the temperature in the oxidation reactor before compressing or pressurizing the air. The compression of the already hot air further heats the air which is then passed in heat exchange with gaseous products of the oxidation reaction for "superheating" the gaseous products prior to the use thereof in turbines as the driving fluid. The superheating of the gaseous products significantly minimizes condensation of gaseous products in the turbine so as to provide a substantially greater recovery of mechanical energy from the process than heretofore achieved.
    Type: Grant
    Filed: March 30, 1979
    Date of Patent: November 18, 1980
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Albert S. Moore, Francis H. Verhoff
  • Patent number: 4228002
    Abstract: A method for increasing the sedimentation of mineral particles in feed liquids containing the same, particularly coal-derived liquids, by the use of an anti-solvent gas pressure technique. The mixture is held under a pressurized carbon dioxide atmosphere which causes an increase in the initial settling rate for sedimentation of the mineral particles from such liquids so that they may be used as fuels.
    Type: Grant
    Filed: September 15, 1978
    Date of Patent: October 14, 1980
    Assignee: Electric Power Research Institute, Inc.
    Inventors: Kumbakonam R. Vaidyanathan, Joseph D. Henry, Jr., Francis H. Verhoff
  • Patent number: 3963624
    Abstract: A clarifier including a lamina comprising a plurality of substantially parallel spaced apart plates extending at an angle to the vertical. The parameters of the lamina are optimized in accordance with disclosed mathematical relationships depending on whether the tank is circular or rectangular. Means for equalizing the flow of the tank are described, as well as means for supplementary removal of additional particulates after the liquid has passed through the lamina.
    Type: Grant
    Filed: January 7, 1974
    Date of Patent: June 15, 1976
    Assignee: Telecommunications Industries, Inc.
    Inventors: Angus D. Henderson, Francis H. Verhoff, John M. Periale