Patents by Inventor Francis J. Martin

Francis J. Martin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190329012
    Abstract: A device for sustained delivery of a poorly water soluble drug is described. A drug reservoir within the device, when in operation, contains an aqueous suspension of the drug mixed with a suspension of an excipient that, in one embodiment, generates acidic groups for a sustained period of time to maintain a desired pH in the aqueous suspension that in turn provides a constant concentration of a soluble form of the drug.
    Type: Application
    Filed: July 10, 2019
    Publication date: October 31, 2019
    Inventors: Francis J. Martin, Ling-Ling Kang
  • Patent number: 10391288
    Abstract: A device for sustained delivery of a poorly water soluble drug is described. A drug reservoir within the device, when in operation, contains an aqueous suspension of the drug mixed with a suspension of an excipient that, in one embodiment, generates acidic groups for a sustained period of time to maintain a desired pH in the aqueous suspension that in turn provides a constant concentration of a soluble form of the drug.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: August 27, 2019
    Assignee: Delpor, Inc.
    Inventors: Francis J. Martin, Ling-Ling Kang
  • Publication number: 20180193253
    Abstract: A drug delivery device that includes a capsule for implantation into the body; the capsule further includes a reservoir for containing a substance such as a therapeutic agent, at least one port for allowing the substance to diffuse from or otherwise exit the reservoir, and a nanopore membrane in communication with the capsule at or near the exit port for controlling the rate of diffusion of the substance from the exit port. The device also includes an optional screen for providing structural stability to the nanopore membrane and for keeping the pores of the nanopore membrane clear. One embodiment of the drug delivery device includes an osmotic engine internal to the device for creating fluid flow through the device.
    Type: Application
    Filed: February 19, 2018
    Publication date: July 12, 2018
    Inventors: Francis J. Martin, Anthony A. Boiarski
  • Publication number: 20170100571
    Abstract: A device for sustained delivery of a poorly water soluble drug is described. A drug reservoir within the device, when in operation, contains an aqueous suspension of the drug mixed with a suspension of an excipient that, in one embodiment, generates acidic groups for a sustained period of time to maintain a desired pH in the aqueous suspension that in turn provides a constant concentration of a soluble form of the drug.
    Type: Application
    Filed: December 22, 2016
    Publication date: April 13, 2017
    Inventors: Francis J. Martin, Ling-Ling Kang
  • Patent number: 9561352
    Abstract: A device for sustained delivery of a poorly water soluble drug is described. A drug reservoir within the device, when in operation, contains an aqueous suspension of the drug mixed with a suspension of an excipient that, in one embodiment, generates acidic groups for a sustained period of time to maintain a desired pH in the aqueous suspension that in turn provides a constant concentration of a soluble form of the drug.
    Type: Grant
    Filed: March 11, 2010
    Date of Patent: February 7, 2017
    Assignee: Delpor, Inc.
    Inventors: Francis J. Martin, Ling-Ling Kang
  • Publication number: 20160374936
    Abstract: A drug delivery device that includes a capsule for implantation into the body; the capsule further includes a reservoir for containing a substance such as a therapeutic agent, at least one port for allowing the substance to diffuse from or otherwise exit the reservoir, and a nanopore membrane in communication with the capsule at or near the exit port for controlling the rate of diffusion of the substance from the exit port. The device also includes an optional screen for providing structural stability to the nanopore membrane and for keeping the pores of the nanopore membrane clear. One embodiment of the drug delivery device includes an osmotic engine internal to the device for creating fluid flow through the device.
    Type: Application
    Filed: August 4, 2016
    Publication date: December 29, 2016
    Inventors: Francis J. Martin, Anthony A. Boiarski
  • Patent number: 9464723
    Abstract: A timing valve includes a moveable piston that has a solid end face at a first end that includes an orifice, an open second end, and side walls that define an enclosed space, a stepped region on an outer surface of the piston, complementary stepped region on an inner surface of a hollow body containing the piston, and an annulus that extends toward the second end defined by a space between the outer surface of the piston and the inner surface of the hollow body. Fluid flowing through the orifice pushes the piston into an open position that forms a space between the stepped and complementary stepped regions that fills with fluid seeping in through the annulus. When pressure on the piston falls below a threshold, the return of the piston to a closed position is slowed by expelling fluid from the space between the stepped and complementary stepped regions.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: October 11, 2016
    Assignee: AUSCO, INC.
    Inventor: Francis J. Martin
  • Patent number: 9433574
    Abstract: A drug delivery device that includes a capsule for implantation into the body; the capsule further includes a reservoir for containing a substance such as a therapeutic agent, at least one port for allowing the substance to diffuse from or otherwise exit the reservoir, and a nanopore membrane in communication with the capsule at or near the exit port for controlling the rate of diffusion of the substance from the exit port. The device also includes an optional screen for providing structural stability to the nanopore membrane and for keeping the pores of the nanopore membrane clear. One embodiment of the drug delivery device includes an osmotic engine internal to the device for creating fluid flow through the device.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: September 6, 2016
    Assignee: Delpor, Inc.
    Inventors: Francis J. Martin, Anthony A. Boiarski
  • Patent number: 9433573
    Abstract: A drug delivery device that includes a capsule for implantation into the body; the capsule further includes a reservoir for containing a substance such as a therapeutic agent, at least one port for allowing the substance to diffuse from or otherwise exit the reservoir, and a nanopore membrane in communication with the capsule at or near the exit port for controlling the rate of diffusion of the substance from the exit port. The device also includes an optional screen for providing structural stability to the nanopore membrane and for keeping the pores of the nanopore membrane clear. One embodiment of the drug delivery device includes an osmotic engine internal to the device for creating fluid flow through the device.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: September 6, 2016
    Assignee: Delpor, Inc.
    Inventors: Francis J. Martin, Anthony A. Boiarski
  • Patent number: 9371926
    Abstract: A pressure relief valve includes a singular body that encloses a seat and a stationary shim, a poppet, within the singular body, that is forced against a seat by a spring attached to the stationary shim, and a pin inserted into the pressure relief valve body to lock the pressure relief valve into a housing bore. The poppet includes a nose extension that extends into a void enclosed by the seat to provide damping. The seat includes a non-threaded stepped region on its outer surface and the singular body includes a complementary stepped region on its inner surface such that when the seat is fit into the singular body, the stepped region of the seat and the complementary stepped region of the singular body interface with each other to prevent movement of the seat toward the spring. The pin includes a coating to reduce friction and galling.
    Type: Grant
    Filed: October 1, 2015
    Date of Patent: June 21, 2016
    Assignee: AUSCO, INC.
    Inventor: Francis J. Martin
  • Patent number: 9271926
    Abstract: A drug delivery device that includes a capsule for implantation into the body; the capsule further includes a reservoir for containing a substance such as a therapeutic agent, at least one port for allowing the substance to diffuse from or otherwise exit the reservoir, and a nanopore membrane in communication with the capsule at or near the exit port for controlling the rate of diffusion of the substance from the exit port. The device also includes an optional screen for providing structural stability to the nanopore membrane and for keeping the pores of the nanopore membrane clear. One embodiment of the drug delivery device includes an osmotic engine internal to the device for creating fluid flow through the device.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: March 1, 2016
    Assignee: DELPOR, INC.
    Inventors: Francis J. Martin, Anthony A. Boiarski
  • Publication number: 20160053903
    Abstract: A timing valve includes a moveable piston that has a solid end face at a first end that includes an orifice, an open second end, and side walls that define an enclosed space, a stepped region on an outer surface of the piston, complementary stepped region on an inner surface of a hollow body containing the piston, and an annulus that extends toward the second end defined by a space between the outer surface of the piston and the inner surface of the hollow body. Fluid flowing through the orifice pushes the piston into an open position that forms a space between the stepped and complementary stepped regions that fills with fluid seeping in through the annulus. When pressure on the piston falls below a threshold, the return of the piston to a closed position is slowed by expelling fluid from the space between the stepped and complementary stepped regions.
    Type: Application
    Filed: August 22, 2014
    Publication date: February 25, 2016
    Inventor: FRANCIS J. MARTIN
  • Publication number: 20160025233
    Abstract: A pressure relief valve includes a singular body that encloses a seat and a stationary shim, a poppet, within the singular body, that is forced against a seat by a spring attached to the stationary shim, and a pin inserted into the pressure relief valve body to lock the pressure relief valve into a housing bore. The poppet includes a nose extension that extends into a void enclosed by the seat to provide damping. The seat includes a non-threaded stepped region on its outer surface and the singular body includes a complementary stepped region on its inner surface such that when the seat is fit into the singular body, the stepped region of the seat and the complementary stepped region of the singular body interface with each other to prevent movement of the seat toward the spring. The pin includes a coating to reduce friction and galling.
    Type: Application
    Filed: October 1, 2015
    Publication date: January 28, 2016
    Inventor: FRANCIS J. MARTIN
  • Patent number: 9200717
    Abstract: A pressure relief valve includes a singular body that encloses a seat and a stationary shim, a poppet, within the singular body, that is forced against a seat by a spring attached to the stationary shim, and a pin inserted into the pressure relief valve body to lock the pressure relief valve into a housing bore. The poppet includes a nose extension that extends into a void enclosed by the seat to provide damping. The seat includes a non-threaded stepped region on its outer surface and the singular body includes a complementary stepped region on its inner surface such that when the seat is fit into the singular body, the stepped region of the seat and the complementary stepped region of the singular body interface with each other to prevent movement of the seat toward the spring. The pin includes a coating to reduce friction and galling.
    Type: Grant
    Filed: October 25, 2013
    Date of Patent: December 1, 2015
    Assignee: AUSCO, INC.
    Inventor: Francis J. Martin
  • Publication number: 20150258017
    Abstract: A drug delivery device that includes a capsule for implantation into the body; the capsule further includes a reservoir for containing a substance such as a therapeutic agent, at least one port for allowing the substance to diffuse from or otherwise exit the reservoir, and a nanopore membrane in communication with the capsule at or near the exit port for controlling the rate of diffusion of the substance from the exit port. The device also includes an optional screen for providing structural stability to the nanopore membrane and for keeping the pores of the nanopore membrane clear. One embodiment of the drug delivery device includes an osmotic engine internal to the device for creating fluid flow through the device.
    Type: Application
    Filed: June 1, 2015
    Publication date: September 17, 2015
    Inventors: Francis J. Martin, Anthony A. Boiarski
  • Publication number: 20150258018
    Abstract: A drug delivery device that includes a capsule for implantation into the body; the capsule further includes a reservoir for containing a substance such as a therapeutic agent, at least one port for allowing the substance to diffuse from or otherwise exit the reservoir, and a nanopore membrane in communication with the capsule at or near the exit port for controlling the rate of diffusion of the substance from the exit port. The device also includes an optional screen for providing structural stability to the nanopore membrane and for keeping the pores of the nanopore membrane clear. One embodiment of the drug delivery device includes an osmotic engine internal to the device for creating fluid flow through the device.
    Type: Application
    Filed: June 1, 2015
    Publication date: September 17, 2015
    Inventors: Francis J. Martin, Anthony A. Boiarski
  • Patent number: 9066875
    Abstract: A drug delivery device that includes a capsule for implantation into the body; the capsule further includes a reservoir for containing a substance such as a therapeutic agent, at least one port for allowing the substance to diffuse from or otherwise exit the reservoir, and a nanopore membrane in communication with the capsule at or near the exit port for controlling the rate of diffusion of the substance from the exit port. The device also includes an optional screen for providing structural stability to the nanopore membrane and for keeping the pores of the nanopore membrane clear. One embodiment of the drug delivery device includes an osmotic engine internal to the device for creating fluid flow through the device.
    Type: Grant
    Filed: November 18, 2013
    Date of Patent: June 30, 2015
    Assignee: Delpor, Inc.
    Inventors: Francis J. Martin, Anthony A. Boiarski
  • Patent number: 9066876
    Abstract: A drug delivery device that includes a capsule for implantation into the body; the capsule further includes a reservoir for containing a substance such as a therapeutic agent, at least one port for allowing the substance to diffuse from or otherwise exit the reservoir, and a nanopore membrane in communication with the capsule at or near the exit port for controlling the rate of diffusion of the substance from the exit port. The device also includes an optional screen for providing structural stability to the nanopore membrane and for keeping the pores of the nanopore membrane clear. One embodiment of the drug delivery device includes an osmotic engine internal to the device for creating fluid flow through the device.
    Type: Grant
    Filed: November 18, 2013
    Date of Patent: June 30, 2015
    Assignee: Delpor, Inc.
    Inventors: Francis J. Martin, Anthony A. Boiarski
  • Publication number: 20150174318
    Abstract: A drug delivery device that includes a capsule for implantation into the body; the capsule further includes a reservoir for containing a substance such as a therapeutic agent, at least one port for allowing the substance to diffuse from or otherwise exit the reservoir, and a nanopore membrane in communication with the capsule at or near the exit port for controlling the rate of diffusion of the substance from the exit port. The device also includes an optional screen for providing structural stability to the nanopore membrane and for keeping the pores of the nanopore membrane clear. One embodiment of the drug delivery device includes an osmotic engine internal to the device for creating fluid flow through the device.
    Type: Application
    Filed: February 12, 2015
    Publication date: June 25, 2015
    Inventors: Francis J. Martin, Anthony A. Boiarski
  • Patent number: 9005650
    Abstract: A drug delivery device that includes a capsule for implantation into the body; the capsule further includes a reservoir for containing a substance such as a therapeutic agent, at least one port for allowing the substance to diffuse from or otherwise exit the reservoir, and a nanopore membrane in communication with the capsule at or near the exit port for controlling the rate of diffusion of the substance from the exit port. The device also includes an optional screen for providing structural stability to the nanopore membrane and for keeping the pores of the nanopore membrane clear. One embodiment of the drug delivery device includes an osmotic engine internal to the device for creating fluid flow through the device.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: April 14, 2015
    Assignee: Delpor, Inc.
    Inventors: Francis J. Martin, Anthony A. Boiarski