Patents by Inventor Francis Jeremiah Meacle

Francis Jeremiah Meacle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the scaleable purification of plasmid DNA
    Patent number: 7285651
    Abstract: The present invention relates to a nonchromatographic-based process for the isolation of clinical grade plasmid DNA from bacterial cells. The exemplified methods described herein outline a scaleable, economically favorable protocol for the purification of clinical grade plasmid DNA from E. coli which includes CTAB-based precipitation of DNA in combination with adsorption of impurities to calcium silicate.
    Type: Grant
    Filed: August 19, 2004
    Date of Patent: October 23, 2007
    Assignee: Merck & Co., Inc.
    Inventors: Russel Jackson Lander, Michael Albert Winters, Francis Jeremiah Meacle
  • Process for the scaleable purification of plasmid DNA
    Patent number: 6797476
    Abstract: The present invention relates to a nonchromatographic-based process for the isolation of clinical grade plasmid DNA from bacterial cells. The exemplified methods described herein outline a scaleable, economically favorable protocol for the purification of clinical grade plasmid DNA from E. coli which includes CTAB-based precipitation of DNA in combination with adsorption of impurities to calcium silicate.
    Type: Grant
    Filed: April 1, 2002
    Date of Patent: September 28, 2004
    Assignee: Merck & Co., Inc.
    Inventors: Russel Jackson Lander, Michael Albert Winters, Francis Jeremiah Meacle
  • Process for the scaleable purification of plasmid DNA
    Publication number: 20020151048
    Abstract: The present invention relates to a nonchromatographic-based process for the isolation of clinical grade plasmid DNA from bacterial cells. The exemplified methods described herein outline a scaleable, economically favorable protocol for the purification of clinical grade plasmid DNA from E. coli which includes CTAB-based precipitation of DNA in combination with adsorption of impurities to calcium silicate.
    Type: Application
    Filed: April 1, 2002
    Publication date: October 17, 2002
    Applicant: Merck & Co., Inc.
    Inventors: Russel Jackson Lander, Michael Albert Winters, Francis Jeremiah Meacle
  • Process for the scaleable purification of plasmid DNA
    Publication number: 20020012990
    Abstract: The present invention relates to a nonchromatographic-based process for the isolation of clinical grade plasmid DNA from bacterial cells. The exemplified methods described herein outline a scaleable, economically favorable protocol for the purification of clinical grade plasmid DNA from E. coli which includes CTAB-based precipitation of DNA in combination with adsorption of impurities to calcium silicate.
    Type: Application
    Filed: June 6, 2001
    Publication date: January 31, 2002
    Inventors: Russel Jackson Lander, Michael Albert Winters, Francis Jeremiah Meacle
  • Process for the scaleable purification of plasmid DNA
    Publication number: 20010044136
    Abstract: The present invention relates to a nonchromatographic-based process for the isolation of clinical grade plasmid DNA from bacterial cells. The exemplified methods described herein outline a scaleable, economically favorable protocol for the purification of clinical grade plasmid DNA from E. coli which includes CTAB-based precipitation of DNA in combination with adsorption of impurities to calcium silicate.
    Type: Application
    Filed: December 21, 2000
    Publication date: November 22, 2001
    Inventors: Russel Jackson Lander, Michael Albert Winters, Francis Jeremiah Meacle