Patents by Inventor Francis Karanu

Francis Karanu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for purifying cells derived from pluripotent stem cells
    Patent number: 10329534
    Abstract: The present invention is directed to methods to differentiate pluripotent stem cells. In particular, the present invention provides methods of characterization of cells differentiated into cells expressing markers characteristic of the pancreatic endocrine lineage utilizing unique surface markers. The present invention also provides methods to enrich or sort cells expressing markers characteristic of the pancreatic endocrine lineage. The present invention also provides methods to deplete cells that may contaminate populations of cells expressing markers characteristic of the pancreatic endocrine lineage formed by the methods of the present invention, thereby reducing the incidence of tumor formation in vivo following transplantation.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: June 25, 2019
    Assignee: Janssen Biotech, Inc.
    Inventors: Francis Karanu, Alireza Rezania
  • METHODS FOR PURIFYING CELLS DERIVED FROM PLURIPOTENT STEM CELLS
    Publication number: 20180258401
    Abstract: The present invention is directed to methods to differentiate pluripotent stem cells. In particular, the present invention provides methods of characterization of cells differentiated into cells expressing markers characteristic of the pancreatic endocrine lineage utilizing unique surface markers. The present invention also provides methods to enrich or sort cells expressing markers characteristic of the pancreatic endocrine lineage. The present invention also provides methods to deplete cells that may contaminate populations of cells expressing markers characteristic of the pancreatic endocrine lineage formed by the methods of the present invention, thereby reducing the incidence of tumor formation in vivo following transplantation.
    Type: Application
    Filed: May 14, 2018
    Publication date: September 13, 2018
    Applicant: JANSSEN BIOTECH, INC.
    Inventors: Francis Karanu, Alireza Rezania
  • Methods for purifying cells derived from pluripotent stem cells
    Patent number: 9969981
    Abstract: The present invention is directed to methods to differentiate pluripotent stem cells. In particular, the present invention provides methods of characterization of cells differentiated into cells expressing markers characteristic of the pancreatic endocrine lineage utilizing unique surface markers. The present invention also provides methods to enrich or sort cells expressing markers characteristic of the pancreatic endocrine lineage. The present invention also provides methods to deplete cells that may contaminate populations of cells expressing markers characteristic of the pancreatic endocrine lineage formed by the methods of the present invention, thereby reducing the incidence of tumor formation in vivo following transplantation.
    Type: Grant
    Filed: February 28, 2011
    Date of Patent: May 15, 2018
    Assignee: Janssen Biotech, Inc.
    Inventors: Francis Karanu, Alireza Rezania
  • Methods for Purifying Cells Derived from Pluripotent Stem Cells
    Publication number: 20110212067
    Abstract: The present invention is directed to methods to differentiate pluripotent stem cells. In particular, the present invention provides methods of characterization of cells differentiated into cells expressing markers characteristic of the pancreatic endocrine lineage utilizing unique surface markers. The present invention also provides methods to enrich or sort cells expressing markers characteristic of the pancreatic endocrine lineage. The present invention also provides methods to deplete cells that may contaminate populations of cells expressing markers characteristic of the pancreatic endocrine lineage formed by the methods of the present invention, thereby reducing the incidence of tumor formation in vivo following transplantation.
    Type: Application
    Filed: February 28, 2011
    Publication date: September 1, 2011
    Applicant: CENTOCOR ORTHO BIOTECH INC.
    Inventors: Francis Karanu, Alireza Rezania