Patents by Inventor Francis M. Reynolds

Francis M. Reynolds has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions Comprising NAv1.7 Selective Inhibitors For Treating Acute, Post-Operative, Or Chronic Pain And Methods Of Using The Same
    Publication number: 20180256502
    Abstract: Provided herein are compositions for treating acute, chronic, or post-operative pain in a subject, said compositions comprising a Nav1.7 selective inhibitor and a biodegradable carrier, wherein the agent is incorporated within the biodegradable carrier. Methods of treating pain in a subject and kits for producing compositions for treating acute, chronic or post-operative pain in in a subject are also disclosed herein.
    Type: Application
    Filed: March 8, 2018
    Publication date: September 13, 2018
    Inventors: Francis M. Reynolds, Jason M. Criscione, Robert Samuel Langer, Dana Tilley, Haining Dai
  • COMPOSITIONS COMPRISING NAv1.7 SELECTIVE INHIBITORS FOR TREATING ACUTE, POST-OPERATIVE, OR CHRONIC PAIN AND METHODS OF USING THE SAME
    Publication number: 20170239183
    Abstract: Provided herein are compositions for treating acute, chronic, or post-operative pain in a subject, said compositions comprising a Nav1.7 selective inhibitor and a biodegradable carrier, wherein the agent is incorporated within the biodegradable carrier. Methods of treating pain in a subject and kits for producing compositions for treating acute, chronic or post-operative pain in a subject are also disclosed herein.
    Type: Application
    Filed: February 22, 2017
    Publication date: August 24, 2017
    Inventors: Francis M. Reynolds, Jason M. Criscione, Robert Samuel Langer, Dana Tilley, Haining Dai
  • Compositions For Treating Acute, Post-Operative, Or Chronic Pain and Methods of Using the Same
    Publication number: 20170224621
    Abstract: Provided herein are compositions for treating acute, chronic, or post-operative pain in a subject, said compositions comprising an anticonvulsant agent and a biodegradable carrier, wherein the agent is incorporated within the biodegradable carrier. Methods of treating pain in a subject and kits for producing compositions for treating acute, chronic or post-operative pain in in a subject are also disclosed herein.
    Type: Application
    Filed: April 25, 2017
    Publication date: August 10, 2017
    Inventors: FRANCIS M. REYNOLDS, JASON M. CRISCIONE, NICHOLAS B. WERTH, ROBERT S. LANGER, HAINING DAI, PATRICK A. ARMSTRONG
  • Compositions For An Injectable, In Situ Forming Neuroscaffold And Methods Of Using The Same
    Publication number: 20170095592
    Abstract: Disclosed are injectable, biodegradable neuroscaffolds formed in situ by self-assembling biodegradable polymeric microparticles, nanoparticles, or any combination thereof, via copper-free click chemistry or Michael-type addition coupling reactions. The injectable, biodegradable neuroscaffolds provide 3-D structural support, neuroprotection, and/or subsequent regeneration in a subject with a spinal cord injury or a focal neurological disorder.
    Type: Application
    Filed: September 30, 2016
    Publication date: April 6, 2017
    Inventors: Jason M. Criscione, Francis M. Reynolds, Haining Dai, Rebecca A. Bader
  • Compositions For Treating Acute, Post-Operative, Or Chronic Pain And Methods of Using The Same
    Publication number: 20160317446
    Abstract: Provided herein are compositions for treating acute, chronic, or post-operative pain in a subject, said compositions comprising an anticonvulsant agent and a biodegradable carrier, wherein the agent is incorporated within the biodegradable carrier. Methods of treating pain in a subject and kits for producing compositions for treating acute, chronic or post-operative pain in in a subject are also disclosed herein.
    Type: Application
    Filed: July 13, 2016
    Publication date: November 3, 2016
    Inventors: JASON M. CRISCIONE, NICHOLAS B. WERTH, ROBERT S. LANGER, FRANCIS M. REYNOLDS, HAINING DAI, PATRICK A. ARMSTRONG, XI CHEN
  • METHODS FOR TREATING EPILEPSY OR SEIZURE DISORDERS
    Publication number: 20160136095
    Abstract: Provided herein are methods for treating epilepsy or seizure disorders comprising administering a composition to a subject, the composition comprising an anticonvulsant agent and a biodegradable carrier, wherein the agent is incorporated within the biodegradable carrier.
    Type: Application
    Filed: November 17, 2015
    Publication date: May 19, 2016
    Inventors: JASON M. CRISCIONE, NICHOLAS B. WERTH, ROBERT S. LANGER, FRANCIS M. REYNOLDS, HAINING DAI, PATRICK A. ARMSTRONG, XI CHEN
  • Compositions For Treating Acute, Post-Operative, or Chronic Pain and Methods of Using the Same
    Publication number: 20160136094
    Abstract: Provided herein are compositions for treating acute, chronic, or post-operative pain in a subject, said compositions comprising an anticonvulsant agent and a biodegradable carrier, wherein the agent is incorporated within the biodegradable carrier. Methods of treating pain in a subject and kits for producing compositions for treating acute, chronic or post-operative pain in in a subject are also disclosed herein.
    Type: Application
    Filed: November 11, 2015
    Publication date: May 19, 2016
    Inventors: JASON M. CRISCIONE, NICHOLAS B. WERTH, ROBERT S. LANGER, FRANCIS M. REYNOLDS, HAINING DAI, PATRICK A. ARMSTRONG, XI CHEN
  • Compositions For Treating Acute, Post-Operative, Or Chronic Pain and Methods of Using the Same
    Publication number: 20160136179
    Abstract: Provided herein are compositions for treating acute, chronic, or post-operative pain in a subject, said compositions comprising an anticonvulsant agent and a biodegradable carrier, wherein the agent is incorporated within the biodegradable carrier. Methods of treating pain in a subject and kits for producing compositions for treating acute, chronic or post-operative pain in in a subject are also disclosed herein.
    Type: Application
    Filed: February 23, 2015
    Publication date: May 19, 2016
    Inventors: JASON M. CRISCIONE, NICHOLAS B. WERTH, ROBERT S. LANGER, FRANCIS M. REYNOLDS, HAINING DAI, Patrick A. Armstrong, Xi Chen
  • COMPOSITIONS FOR INHIBITING INFLAMMATION IN A SUBJECT WITH A SPINAL CORD INJURY AND METHODS OF USING THE SAME
    Publication number: 20160045439
    Abstract: Provided herein are compositions for inhibiting inflammation in a subject with a spinal cord injury comprising one or more agents capable of specifically reducing TNF-? signaling and a biodegradable carrier. Further provided herein are compositions for inhibiting inflammation in a subject with a spinal cord injury comprising one or more agents capable of modulating MCP-1 signaling and a biodegradable carrier. Methods of treating inflammation in a subject having a spinal cord injury and kits for producing the compositions are also disclosed.
    Type: Application
    Filed: August 14, 2015
    Publication date: February 18, 2016
    Inventors: JASON M. CRISCIONE, FRANCIS M. REYNOLDS, HAINING DAI
  • SPINAL CORD INJURY, INFLAMMATION, AND IMMUNE-DISEASE: LOCAL CONTROLLED RELEASE OF THERAPEUTIC AGENTS
    Publication number: 20150148317
    Abstract: A drug delivery system is provided for treatment of oxidative stress. The drug delivery system can include a therapeutic agent and a matrix. The therapeutic agent can include an antioxidant or steroid. The matrix can include a hydrogel, particle, microparticle, or nanoparticle. A method of treating injury, including peripheral nerve injury or spinal cord injury, is also provided. The method includes injecting the drug delivery system at the site of injury.
    Type: Application
    Filed: November 26, 2014
    Publication date: May 28, 2015
    Applicants: InVivo Therapeutics Corporation, Massachusetts Institute of Technology
    Inventors: Christopher D. Pritchard, Robert S. Langer, Francis M. Reynolds, Eric J. Woodard
  • CUPPED FORCEPS
    Publication number: 20140012314
    Abstract: Cupped forceps are provided. Methods of using a cupped forceps are provided.
    Type: Application
    Filed: June 28, 2013
    Publication date: January 9, 2014
    Applicant: InVivo Therapeutics Corporation
    Inventors: Haining William Dai, Brian Hess, Francis M. Reynolds, David Kosh, Fioleda Prifti
  • SPINAL CORD INJURY, INFLAMMATION, AND IMMUNE-DISEASE: LOCAL CONTROLLED RELEASE OF THERAPEUTIC AGENTS
    Publication number: 20130324509
    Abstract: A drug delivery system is provided for treatment of oxidative stress. The drug delivery system can include a therapeutic agent and a matrix. The therapeutic agent can include an antioxidant or steroid. The matrix can include a hydrogel, particle, microparticle, or nanoparticle. A method of treating injury, including peripheral nerve injury or spinal cord injury, is also provided. The method includes injecting the drug delivery system at the site of injury.
    Type: Application
    Filed: August 8, 2013
    Publication date: December 5, 2013
    Applicant: InVivo Therapeutics Corporation
    Inventors: Christopher D. Pritchard, Robert S. Langer, Francis M. Reynolds, Eric J. Woodard
  • SPINAL CORD INJURY, INFLAMMATION AND IMMUNE-DISEASE: LOCAL CONTROLLED RELEASE OF THERAPEUTIC AGENTS
    Publication number: 20130324500
    Abstract: A drug delivery system is provided for treatment of oxidative stress. The drug delivery system can include a therapeutic agent and a matrix. The therapeutic agent can include an antioxidant or steroid. The matrix can include a hydrogel, particle, microparticle, or nanoparticle. A method of treating injury, including peripheral nerve injury or spinal cord injury, is also provided. The method includes injecting the drug delivery system at the site of injury.
    Type: Application
    Filed: August 8, 2013
    Publication date: December 5, 2013
    Applicant: InVivo Therapeutics Corporation
    Inventors: Christopher D. Pritchard, Robert S. Langer, Francis M. Reynolds, Eric J. Woodard
  • PROTECTIVE PACKAGING WITH PRODUCT PREPARATION FEATURES INCORPORATED
    Publication number: 20130233736
    Abstract: A protective packaging with one or more product preparation features is provided.
    Type: Application
    Filed: March 11, 2013
    Publication date: September 12, 2013
    Applicant: INVIVO THERAPEUTICS CORPORATION
    Inventors: Brian Hess, Francis M. Reynolds, Edward Wirth, III, John M. Harvey, Celina Chang, Haining Dai, Fioleda Prifti
  • SPINAL CORD INJURY, INFLAMMATION, AND IMMUNE-DISEASE: LOCAL CONTROLLED RELEASE OF THERAPEUTIC AGENTS
    Publication number: 20100196481
    Abstract: A drug delivery system is provided for treatment of oxidative stress. The drug delivery system can include a therapeutic agent and a matrix. The therapeutic agent can include an antioxidant or steroid. The matrix can include a hydrogel, particle, microparticle, or nanoparticle. A method of treating injury, including peripheral nerve injury or spinal cord injury, is also provided. The method includes injecting the drug delivery system at the site of injury.
    Type: Application
    Filed: September 25, 2009
    Publication date: August 5, 2010
    Applicant: INVIVO THERAPEUTICS CORPORATION
    Inventors: Christopher D. Pritchard, Robert S. Langer, Francis M. Reynolds, Eric J. Woodard