Abstract: The present invention includes compositions that are useful in the treatment of breathing control diseases or disorders in a subject in need thereof. The present invention also includes a method of treating a respiratory disease or disorder in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a pharmaceutical formulation of the invention. The present invention further includes a method of preventing destabilization or stabilizing breathing rhythm in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a pharmaceutical formulation of the invention.

Abstract: The present invention includes compounds, and compositions comprising the same, that are useful in the treatment of breathing control diseases or disorders in a subject in need thereof. The present invention also includes a method of treating a respiratory disease or disorder in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound of the invention. The present invention further includes a method of preventing destabilization or stabilizing breathing rhythm in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound of the invention.

Abstract: The present invention includes compounds, and compositions comprising the same, that are useful in the treatment of breathing control diseases or disorders in a subject in need thereof. The present invention also includes a method of treating a respiratory disease or disorder in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound of the invention. The present invention further includes a method of preventing destabilization or stabilizing breathing rhythm in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound of the invention.

Abstract: The present invention includes compositions that are useful in the treatment of breathing control diseases or disorders in a subject in need thereof. The present invention also includes a method of treating a respiratory disease or disorder in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a pharmaceutical formulation of the invention. The present invention further includes a method of preventing destabilization or stabilizing breathing rhythm in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a pharmaceutical formulation of the invention.

Abstract: A cold gas inflator has a pressure vessel made of first and second cylindrical members that are joined by friction welding, the friction welding producing curls that serve to preclude an orifice plate from sliding into the second cylindrical member. The cold gas inflator is filled with stored gas. The cold gas inflator has a burst disk, which prevents the stored gas from exiting the pressure vessel. In the event of an automobile accident, an opening device is actuated, which causes the ignition of pyrotechnic material. This ignition generates a shockwave of sufficient energy to rupture a burst disk. The stored gas flows from the cold gas inflator in a radial direction.

Abstract: A cold gas inflator having an opening device for rupturing a burst disk. The cold gas inflator is filled with stored gas. The cold gas inflator has a burst disk, which prevents the stored gas from exiting the pressure vessel. In the event of a automobile accident, the opening device is actuated, which causes the ignition of pyrotechnic material. This ignition generates a shockwave of sufficient energy to rupture the burst disk. The stored gas flows into the diffuser and then exits the cold gas inflator in the radial direction. In another embodiment, the stored gas exits the cold gas inflator in the axial direction.

Abstract: A cold gas inflator having an opening device for rupturing a burst disk. The cold gas inflator is filled with stored gas. The cold gas inflator has a burst disk, which prevents the stored gas from exiting the pressure vessel. In the event of an automobile accident, the opening device is actuated, which causes the ignition of pyrotechnic material. This ignition generates a shockwave of sufficient energy to rupture the burst disk. The stored gas flows from the cold gas inflator in the radial direction. In another embodiment, the stored gas exits the cold gas inflator in the axial direction.

Abstract: A cold gas inflator having an opening device for rupturing a burst disk. The cold gas inflator is filled with stored gas. The cold gas inflator has a burst disk, which prevents the stored gas from exiting the pressure vessel. In the event of a automobile accident, the opening device is actuated, which causes the ignition of pyrotechnic material. This ignition generates a shockwave of sufficient energy to rupture the burst disk. The stored gas flows into the diffuser and then exits the cold gas inflator in the radial direction. In another embodiment, the stored gas exits the cold gas inflator in the axial direction.

Abstract: A method of determining the volume flow of a fluid through a conduit usable with a single crystal, whereby at least one of the fluid and the conduit have energy-scattering interfaces. The method in one embodiment includes transmitting a known, uniform sound field through the fluid which illuminates the entire cross-sectional area of the conduit, obtaining the Doppler signal from the received signal such that the sampling region is normal to the direction of propagation of the sound field; and obtaining the integral of the power over this surface. A known volume of fluid totally within the conduit is then sampled for the reference power return therefrom and this reference power return is divided into the first moment of the power to produce a signal proportional to the volume flow of the fluid through the conduit.

Abstract: A catheter probe flow meter and method of determining the volume flow of a fluid through a conduit, at least one of the fluid and the conduit having energy-scattering interfaces. The method in one embodiment includes trasmitting at least two and receiving at least one or transmitting at least one and receiving at least two sound beams through the fluid, resolving the Doppler vectors into an average velocity vector for each transmitting/receiving combination, and resolving the resolved velocity vectors into their component parts.

Abstract: A catheter probe flow meter and method of determining the volume flow of a fluid through a conduit, at least one of the fluid and the conduit having energy-scattering interfaces. The method in one embodiment includes transmitting at least two and receiving at least one or transmitting at least one and receiving at least two sound beams through the fluid, resolving the Doppler vectors into an average velocity vector for each transmitting/receiving combination, and resolving the resolved velocity vectors into their component parts.