Patents by Inventor Francis Murigi

Francis Murigi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR PRODUCTION OF NOVEL GALETERONE ANALOGS AND USES THEREOF
    Publication number: 20190169227
    Abstract: Galeterone and its C-3 analogs are of substantial interest because of their multi-target anticancer activities, including AR and Mnk degrading activities. Provided are novel procedures for gram-scale, high-yield synthesis of C-3 analogs of galeterone, including 3?-(1H-imidazole-1-yl)-17-(1H-benzimidazole-1-yl)-androsta-5,16-diene (galeterone 3?-imidazole) and 3?-(pyridine-4-ylmethoxy)-17-(1H-benzimidazol-1-yl)androsta-5,16-diene (galeterone 3?-pyridine methoxylate).
    Type: Application
    Filed: June 22, 2017
    Publication date: June 6, 2019
    Applicant: UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Vincent C.O. Njar, Puranik Purushottamachar, Francis Murigi