Abstract: A packaging substrate can include a first surface and a second opposing surface, the first surface including a first mounting region of a first electronic module region and the second opposing surface including a first electrical contacts region of the first electronic module region. The packaging substrate can include a saw street region with at least a portion that surrounds the first electronic module region, and a saw street feature formed on the second opposing surface within at least a portion of the saw street region, the saw street feature being a solder mask layer over a metal layer.

Abstract: Substituted quinazoline compounds, conjugates, and pharmaceutical compositions for use in the treatment of cancer are disclosed herein. The disclosed compounds are useful, among other things, in the inhibition of CDK. In certain aspects, the disclosure generally relates to substituted quinolinone amide compounds or salts of Formula (I), (IA), (IAA), (IAAA), (IB), (IBB), (IC), (ICC), (II), or (IIA) and pharmaceutical compositions thereof.

Abstract: A binary photonics lattice that includes a waveguide array having a plurality of single mode waveguides disposed in a substrate, the plurality of single mode waveguides including one or more first waveguides having a first V-number V1 and one or more second waveguides having a second V-number V2. The first V-number V1 is smaller than the second V-number V2. The one or more first and second waveguides are arranged in a linear distribution having first and second edge waveguide regions and a binary waveguide region positioned between the first and second edge waveguide regions. The binary waveguide region is a symmetrical binary representation of a decimal number of two or greater. Further, the binary waveguide region includes at least one first waveguide representing a digit 0 of the symmetrical binary representation and/or at least one second waveguide representing a digit 1 of the symmetrical binary representation.

Abstract: Prior arrangement information is automatically fetched in response to detection that a radio presence advertising mobile device of a user is disposed in a region of interest that is operatively adjacent to a transaction-processing location. The fetched information is used to automatically modify the transaction.

Abstract: A radio presence-advertising signal (PAS) a PAS emitter is simultaneously received at two or more co-located directional antennas that are coupled to respective radio receivers. The antennas have reception sensitivity lobes that overlap to define a region of interest at the overlap. Substantially cotemporaneous signal strength indications are obtained from the radio receivers. A difference signal representative of a difference between two of the obtained signal strength indications of the respective antennas is generated. An average signal representative of a running average of two or more of the obtained signal strength indications is generated and used to produce a normalized confidence indicator indicating a level of confidence that the PAS emitter is disposed inside (e.g., centered in) the region of interest or alternatively indicating a level of confidence that the PAS emitter is disposed outside the region of interest. Action is taken or avoided based on the confidence signal.

Abstract: A system and method for rating equity crowdfunding capital raises is disclosed. The method includes receiving a set of equity raise metrics associated with one or more companies from an external database and obtaining a plurality of datapoints of the set of equity raises from the external database. The method further includes calculating a set of z-scores corresponding to each of the plurality of datapoints and generating a set of scores for each of the set of equity raise metrics associated with the one or more companies. Further, the method includes determining an overall raise rating of each of the one or more companies and outputting the generated set of scores and the determined overall raise rating on user interface screen of one or more electronic devices associated with one or more users.

Abstract: Prior arrangement information is automatically fetched in response to detection that a radio presence advertising mobile device of a user is disposed in a region of interest that is operatively adjacent to a transaction-processing location. The fetched information is used to automatically modify the transaction.

Abstract: A radio presence-advertising signal (PAS) a PAS emitter is simultaneously received at two or more co-located directional antennas that are coupled to respective radio receivers. The antennas have reception sensitivity lobes that overlap to define a region of interest at the overlap. Substantially cotemporaneous signal strength indications are obtained from the radio receivers. A difference signal representative of a difference between two of the obtained signal strength indications of the respective antennas is generated. An average signal representative of a running average of two or more of the obtained signal strength indications is generated and used to produce a normalized confidence indicator indicating a level of confidence that the PAS emitter is disposed inside (e.g., centered in) the region of interest or alternatively indicating a level of confidence that the PAS emitter is disposed outside the region of interest. Action is taken or avoided based on the confidence signal.

Abstract: The disclosure relates to technology for determining a location of a user in a physical venue, the method comprising receiving, at a central processor, a signal from a wireless transmitter in the user's possession, the signal containing an encoded message and additional metadata, determining a location of the wireless transmitter in the physical venue based on the encoded message and the additional metadata, and outputting the location.

Abstract: The disclosure relates to technology for determining a location of a user in a physical venue, the method comprising receiving, at a central processor, a signal from a wireless transmitter in the user's possession, the signal containing an encoded message and additional metadata, determining a location of the wireless transmitter in the physical venue based on the encoded message and the additional metadata, and outputting the location.

Abstract: The disclosure relates to technology for determining a location of a user in a physical venue, the method comprising receiving, at a central processor, a signal from a wireless transmitter in the user's possession, the signal containing an encoded message and additional metadata, determining a location of the wireless transmitter in the physical venue based on the encoded message and the additional metadata, and outputting the location.

Abstract: A light-emitting diode includes at least one light-emitting diode chip, a carrier for the at least one light-emitting diode chip, and at least one control device integrated into the carrier, wherein each of the light-emitting diode chips is electrically connected to one of the at least one control devices, each of the at least one control devices includes a data storage device in which brightness data for each light-emitting diode chip which is connected to the control device is stored, and the control device drives the connected light-emitting diode chip with a current which is selected according to stored brightness data for the light-emitting diode chip.

Abstract: A light-emitting diode includes at least one light-emitting diode chip, a carrier for the at least one light-emitting diode chip, and at least one control device integrated into the carrier, wherein each of the light-emitting diode chips is electrically connected to one of the at least one control devices, each of the at least one control devices includes a data storage device in which brightness data for each light-emitting diode chip which is connected to the control device is stored, and the control device drives the connected light-emitting diode chip with a current which is selected according to stored brightness data for the light-emitting diode chip.

Abstract: A light-emitting diode includes at least one light-emitting diode chip, at least one control device, wherein each of the light-emitting diode chips is electrically connected to one of the at least one control devices, each of the at least one control devices including a data storage device in which brightness data for each light-emitting diode chip which is connected to the control device is stored, and the control device drives the connected light-emitting diode chip with a current which is selected according to stored brightness data for the light emitting-diode chip.

Abstract: A light-emitting diode includes at least one light-emitting diode chip, at least one control device, wherein each of the light-emitting diode chips is electrically connected to one of the at least one control devices, each of the at least one control devices including a data storage device in which brightness data for each light-emitting diode chip which is connected to the control device is stored, and the control device drives the connected light-emitting diode chip with a current which is selected according to stored brightness data for the light emitting-diode chip.

Abstract: According to at least one embodiment of the invention an illumination device emitting light with an average color comprises a plurality of first light-emitting diodes (LEDs) emitting light with a first color and a plurality of second light-emitting diodes (LEDs) emitting light with a second color, wherein the average color is a superposition of the first and the second color.

Abstract: According to at least one embodiment of the invention an illumination device emitting light with an average color comprises a plurality of first light-emitting diodes (LEDs) emitting light with a first color and a plurality of second light-emitting diodes (LEDs) emitting light with a second color, wherein the average color is a superposition of the first and the second color.

Abstract: The present invention involves the preparation of vascular endothelial growth factor (VEGF) antagonist molecules comprising variant VEGF polypeptides which are capable of binding to and occupying cell surface VEGF receptors without inducing a VEGF response, thereby antagonizing the biological activity of the native VEGF protein. Specifically, the variant VEGF polypeptides of the present invention comprise modifications of at least one cysteine residue in the native VEGF sequence, thereby inhibiting the ability of the variant polypeptide to dimerize through the formation of disulfide bonds. The present invention is further directed to methods for preparing such variant VEGF antagonists and to methods, compositions and assays utilizing such variants for producing pharmaceutically active materials having therapeutic and pharmacologic properties that differ from the native VEGF protein.

Abstract: The present invention involves the preparation of vascular endothelial growth factor (VEGF) variants which provide materials that are selective in respect of binding characteristics to the kinase domain region and the FMS-like tyrosine-kinase region, respectively KDR and FLT-1. The respective KDR and FLT-1 receptors are bound by corresponding domains within the VEGF compound domains. The variants hereof define those two binding regions and modify them so as to introduce changes that interrupt the binding to the respective domain. In this fashion the final biological characteristics of the VEGF molecule are selectively modified.