Patents by Inventor Francis P. Gailliot

Francis P. Gailliot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes for isolation and purification of enfumafungin
    Patent number: 8674087
    Abstract: The present disclosure relates to processes useful in the isolation and purification of enfumafungin, which is classified as a triterpene glycoside antifungal compound and acts as a glucan synthase inhibitor. Enfumafungin has application in the treatment of conditions caused by fungal infection and is also useful as an intermediate in the preparation of other compounds useful as antifungal agents and/or inhibitors of (1,3)-?-D-glucan synthesis.
    Type: Grant
    Filed: August 30, 2010
    Date of Patent: March 18, 2014
    Assignee: Scynexis, Inc.
    Inventors: Jennifer M. Pollard, Rebecca A. Chmielowski, Lisa M. Dietrich, Francis P. Gailliot, Kent Goklen
  • PROCESSES FOR ISOLATION AND PURIFICATION OF ENFUMAFUNGIN
    Publication number: 20120165513
    Abstract: The present disclosure relates to processes useful in the isolation and purification of enfumafungin, which is classified as a triterpene glycoside antifungal compound and acts as a glucan synthase inhibitor. Enfumafungin has application in the treatment of conditions caused by fungal infection and is also useful as an intermediate in the preparation of other compounds useful as antifungal agents and/or inhibitors of (1,3)-?-D-glucan synthesis.
    Type: Application
    Filed: August 30, 2010
    Publication date: June 28, 2012
    Inventors: Jennifer M. Pollard, Rebecca A. Chmielowski, Lisa M. Dietrich, Francis P. Gailliot, Kent Goklen
  • Conversion of indene to (1S)-amino-(2R)-indanol free of any stereoisomer, by combination of dioxygenase bioconversion and chemical steps
    Patent number: 5858737
    Abstract: A process is disclosed that bioconverts indene to (1S)-amino-(2R)-indanol substantially free of any of its stereoisomers, by the action of a strain of P. putida or Rhodococcus sp., followed by various chemical step(s), e.g., chiral specific crystallization, treatment with strong acid in the presence of acetonitrile.
    Type: Grant
    Filed: August 14, 1996
    Date of Patent: January 12, 1999
    Assignee: Merck & Co., Inc.
    Inventors: Barry C. Buckland, Neal C. Connors, Michel M. Chartrain, Francis P. Gailliot, Randolph L. Greasham, Barbara Jackey, Brian Heimbuch, Chanyong Lee, Roger C. Olewinski, Jr., F. Edward Roberts, Paul J. Reider, Thomas R. Verhoeven, Chris H. Senanayake