Patents by Inventor Francis P. Kuhajda

Francis P. Kuhajda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of fatty acid synthesis as antimicrobial agents
    Patent number: 5614551
    Abstract: Fatty acid synthase (FAS) is overexpressed by certain infectious organisms that are resistant to most currently available antibiotics. Contrarywise, little FAS expression is identified in patient tissues. Inhibition of fatty acid synthesis is thus selectively toxic to invasive cells, while patient cells with low FAS activity are resistant. This invention provides a method of treating septic patients where fatty acid synthesis by invading cells is inhibited with resultant interruption of the disease process.
    Type: Grant
    Filed: January 24, 1994
    Date of Patent: March 25, 1997
    Assignee: The Johns Hopkins University
    Inventors: James D. Dick, Francis P. Kuhajda