Patents by Inventor Francis X. Ignatious

Francis X. Ignatious has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lactone bearing absorbable polymers
    Patent number: 7205378
    Abstract: The present invention pertains to biodegradable polymers comprising a non-polymerizable lactone, biodegradable compositions comprising the polymer and a therapeutic agent, the use of the compositions for the sustained release of therapeutic agents, wherein the therapeutic agent is reversibly immobilized on the polymer matrix using ionic complexation between the latent carboxylic groups present on the lactone bearing polymer matrix and a cationic group on the therapeutic agent.
    Type: Grant
    Filed: April 26, 2005
    Date of Patent: April 17, 2007
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques, SAS
    Inventor: Francis X. Ignatious
  • Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides
    Patent number: 7005420
    Abstract: A copolymer comprising an N-acylated derivative, and a composition comprising said copolymer and a polypeptide, said polypeptide comprising at least one effective ionogenic amine, wherein at least 50 percent, by weight, of said polypeptide present in said composition is ionically bound to said polymer.
    Type: Grant
    Filed: July 27, 2004
    Date of Patent: February 28, 2006
    Assignee: Ipsen Manufacturing Ireland Limited
    Inventors: Shalaby W. Shalaby, Ruth M. Russell, Jacques-Pierre Moreau, Steven A. Jackson, Francis X. Ignatious
  • Lactone bearing absorbable polymers
    Patent number: 6955822
    Abstract: The present invention pertains to biodegradable polymers comprising a non-polymerizable lactone, biodegradable compositions comprising the polymer and a therapeutic agent the use of the compositions for the sustained release of therapeutic agents, wherein the therapeutic agent is reversibly immobilized on the polymer matrix using ionic complexation between the latent carboxylic groups present on the lactone bearing polymer matrix and a cationic group on the therapeutic agent.
    Type: Grant
    Filed: November 2, 1999
    Date of Patent: October 18, 2005
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques, SAS of Paris
    Inventor: Francis X. Ignatious
  • Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides
    Patent number: 6794364
    Abstract: A copolymer comprising an N-acylated derivative, and a composition comprising said copolymer and a polypeptide, said polypeptide comprising at least one effective ionogenic amine, wherein at least 50 percent, by weight, of said polypeptide present in said composition is ionically bound to said polymer.
    Type: Grant
    Filed: September 20, 2002
    Date of Patent: September 21, 2004
    Assignee: Kinerton Limited
    Inventors: Shalaby W. Shalaby, Steven A. Jackson, Francis X. Ignatious, Jacques-Pierre Moreau, Ruth M. Russell
  • Ionic molecular conjugates of n-acylated derivatives of poly(2-amino-2-deoxy-d-glucose) and polypeptides
    Publication number: 20030092800
    Abstract: A copolymer comprising an N-acylated derivative, and a composition comprising said copolymer and a polypeptide, said polypeptide comprising at least one effective ionogenic amine, wherein at least 50 percent, by weight, of said polypeptide present in said composition is ionically bound to said polymer.
    Type: Application
    Filed: September 20, 2002
    Publication date: May 15, 2003
    Applicant: Biomeasure, Inc.
    Inventors: Shalaby W. Shalaby, Steven A. Jackson, Francis X. Ignatious, Jacques-Pierre Moreau, Ruth M. Russell
  • Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides
    Patent number: 6479457
    Abstract: A copolymer comprising an N-acylated derivative, and a composition comprising said copolymer and a polypeptide, said polypeptide comprising at least one effective ionogenic amine, wherein at least 50 percent, by weight, of said polypeptide present in said composition is ionically bound to said polymer.
    Type: Grant
    Filed: October 9, 1998
    Date of Patent: November 12, 2002
    Assignee: Kinerton Limited
    Inventors: Shalaby W. Shalaby, Steven A. Jackson, Francis X. Ignatious, Jacques-Pierre Moreau, Ruth M. Russell
  • IONIC MOLECULAR CONJUGATES OF N-ACYLATED DERIVATIVES OF POLY(2-AMINO-2-DEOXY-D-GLUCOSE) AND POLYPEPTIDES
    Publication number: 20020098206
    Abstract: A copolymer comprising an N-acylated derivative, and a composition comprising said copolymer and a polypeptide, said polypeptide comprising at least one effective ionogenic amine, wherein at least 50 percent, by weight, of said polypeptide present in said composition is ionically bound to said polymer.
    Type: Application
    Filed: October 9, 1998
    Publication date: July 25, 2002
    Inventors: SHALABY W. SHALABY, STEVEN A. JACKSON, FRANCIS X. IGNATIOUS, JACQUES-PIERRE MOREAU, RUTH M. RUSSELL
  • Encapsulation of water soluble peptides
    Patent number: 6270700
    Abstract: This invention relates to a process for preparing biodegradable microspheres and or nanospheres using an oil-in-water process for the controlled release of bioactive peptides.
    Type: Grant
    Filed: July 20, 1999
    Date of Patent: August 7, 2001
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques, SAS
    Inventor: Francis X. Ignatious