Abstract: Process and system for calculating distances between wireless nodes. The process includes, in order to determine the RTT between a node to be positioned and a reference node: providing a time-stamping software layer above the physical layer, and using it to assign and register timestamps to the inputs and outputs of data frames received and to be sent by the node to be positioned; processing, by means of a link software layer, the data frames received and to be sent by the latter; and providing a binding software layer, above said link software layer, and using it to access the timestamps registered and the data frames received and to be sent, and binding them to one another. The system includes a wireless node to be positioned configured to implement the process proposed by the process.