Abstract: Provided are a system, method, and computer program product for network anomaly detection. The method includes determining a plurality of nested groups based on event data associated with a plurality of communications in a computer network. The method also includes generating display data configured to cause a display of a computing device to show a first graphical representation of the event data including a plurality of nested graphical nodes. The method further includes receiving new event data associated with a plurality of new communications in the computer network in a subsequent time period and generating new display data configured to cause the display to show a new graphical representation of the new event data. The method further includes determining an anomalous graphical node based at least partly on a size of the anomalous graphical node being increased in the new graphical representation relative to the first graphical representation.

Abstract: Provided are a system, method, and computer program product for network anomaly detection. The method includes receiving event data associated with a plurality of events in a computer network. The method also includes determining nested groups of the event data representing tiers of an operational hierarchy. The method further includes generating display data to show a graphical representation of the event including a plurality of nested graphical nodes and at least one spline. Each graphical node is associated with a group or a computer node, each graphical node encompasses and/or is encompassed by another graphical node, a size of each graphical node is proportional to an aggregated parameter value of events associated therewith, each spline connects at least two graphical nodes and includes a curve that passes through a common graphical node, and each spline is associated with a communication between at least two computer nodes.

Abstract: This invention relates to: (a) compounds of formula Ia (with R1, R4 to R6, n and A as defined herein) and pharmaceutically acceptable salts or solvates thereof that are useful as dopamine-p-hydroxylase inhibitors; (b) pharmaceutical compositions (comprising such compounds, salts or solvates; (c) the use of such compounds, salts or solvates in therapy; (d) therapeutic methods of treatment using such compounds, salts or solvates; and (e) processes and intermediates useful for the synthesis of such compounds.

Abstract: Provided are a system, method, and computer program product for network anomaly detection. The method includes receiving event data associated with a plurality of events in a computer network. The method also includes determining nested groups of the event data representing tiers of an operational hierarchy. The method further includes generating display data to show a graphical representation of the event including a plurality of nested graphical nodes and at least one spline. Each graphical node is associated with a group or a computer node, each graphical node encompasses and/or is encompassed by another graphical node, a size of each graphical node is proportional to an aggregated parameter value of events associated therewith, each spline connects at least two graphical nodes and includes a curve that passes through a common graphical node, and each spline is associated with a communication between at least two computer nodes.

Abstract: This invention relates to: (a) compounds of formula Ia (with R1, R4 to R6, n and A as defined herein) and pharmaceutically acceptable salts or solvates thereof that are useful as dopamine-?-hydroxylase inhibitors; (b) pharmaceutical compositions (comprising such compounds, salts or solvates; (c) the use of such compounds, salts or solvates in therapy; (d) therapeutic methods of treatment using such compounds, salts or solvates; and (e) processes and intermediates useful for the synthesis of such compounds.

Abstract: This invention relates to: (a) compounds of formula I (with R1 to R5 and A as defined herein) and pharmaceutically acceptable salts or solvates thereof that are useful as dopamine-?-hydroxylase inhibitors; (b) pharmaceutical compositions comprising such compounds, salts or solvates; (c) the use of such compounds, salts or solvates in therapy; (d) therapeutic methods of treatment using such compounds, salts or solvates; and (e) processes and intermediates useful for the synthesis of such compounds.

Abstract: This invention relates to: (a) compounds of formula Ia (with R1, R4 to R6, n and A as defined herein) and pharmaceutically acceptable salts or solvates thereof that are useful as dopamine-?-hydroxylase inhibitors; (b) pharmaceutical compositions (comprising such compounds, salts or solvates; (c) the use of such compounds, salts or solvates in therapy; (d) therapeutic methods of treatment using such compounds, salts or solvates; and (e) processes and intermediates useful for the synthesis of such compounds.

Abstract: The function of the multispirometer and procedure to measure the ventilatory function by spirometry is to know how a person exhales or expels air with the objective to study and monitor the functioning of his/her lungs and many pathologies. By means of this method, the ventilatory function by spirometry is measured, and is capable of obtaining respiratory restriction and obstruction values of a patient. To perform the above mentioned method, an electronic spirometer provided with flow detector means, microprocessor control means to carry out calculations on the basis of measured data, and means associated to said microprocessor to store the measured results, to visualize the results and to compare the stored results, is used.

Abstract: The function of the multispirometer and procedure to measure the ventilatory function by spirometry is to know how a person exhales or expels air with the objective to study and monitor the functioning of his/her lungs and many pathologies. By means of this method, the ventilatory function by spirometry is measured, and is capable of obtaining respiratory restriction and obstruction values of a patient. To perform the above mentioned method, an electronic spirometer provided with flow detector means, microprocessor control means to carry out calculations on the basis of measured data, and means associated to said microprocessor to store the measured results, to visualize the results and to compare the stored results, is used.