Patents by Inventor Francisco Esteva

Francisco Esteva has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnostic and therapeutic methods and compositions involving PTEN and breast cancer
    Publication number: 20050287543
    Abstract: Patients with ErbB2-overexpressing cancers can be given an ErbB2 targeting agent as a therapeutic regimen but not all patients are responsive. The present invention concerns the diagnostic, prognostic and therapeutic methods and compositions for evaluating potential efficacy of an ErbB2 targeting agent in an ErbB2-overexpressing cancers by evaluating PTEN expression, which is predictive of responsiveness or resistance to ErbB2 targeting agents such as trastuzumab. Low PTEN expression is predictive of a patient who will respond poorly to trastuzumab.
    Type: Application
    Filed: November 5, 2004
    Publication date: December 29, 2005
    Inventors: Dihua Yu, Xiaoyan Zhou, Yoichi Nagata, Francisco Esteva, Aysegul Sahin