Patents by Inventor Francisco J. Rosales
Francisco J. Rosales has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9439448Abstract: A nutritional composition for improving the immunological function of a subject, including a lipid or fat; a protein source; about 5 to about 100 mg/100 kcal of a source of long chain polyunsaturated fatty acids which comprises docosahexanoic acid; and about 0.1 to about 1 mg/100 kcal of a prebiotic composition, wherein the prebiotic composition comprises at least 20% of an oligosaccharide which has a fermentation rate which is demonstrably slower than that of galacto-oligosaccharide.Type: GrantFiled: September 14, 2012Date of Patent: September 13, 2016Assignee: Mead Johnson Nutrition CompanyInventors: Francisco J. Rosales, Eric van Tol, Gyan P. Rai, Kristin Morris, Dattatreya Banavera, Dirk Hondmann, Zeina E. Jouni, Robert J. McMahon, Deborah A. Schade, Donald Carey Walker
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Patent number: 9386794Abstract: A nutritional composition having a lipid or fat; a protein source; a source of long chain polyunsaturated fatty acids which comprises docosahexanoic acid; and up to about 2.5% by weight of a source of supplemental calcium which, when dissociated, provides a cation having prebiotic functionality.Type: GrantFiled: May 11, 2009Date of Patent: July 12, 2016Assignee: Mead Johnson Nutrition CompanyInventors: Francisco J. Rosales, Gyan P. Rai, Kristin Morris, Dattatreya Banavara, Eric van Tol, Zeina E. Jouni, Robert J. McMahon, Deborah A. Schade, Donald Carey Walker
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Patent number: 8367354Abstract: A novel method for determining the levels of TGF-?1 or TGF-?2 in a sample of milk, raw protein source, or nutritional composition is provided. The method involves, in some cases, reconstituting the sample; in some cases, centrifuging the sample; activating the sample using particular ratios of sample:acid:base; diluting the sample using particular ratios of sample:buffer agent; and determining the concentration of TGF-?1 in the sample using an ELISA assay.Type: GrantFiled: February 12, 2009Date of Patent: February 5, 2013Assignee: Mead Johnson Nutrition CompanyInventors: Gyan P. Rai, Francisco J. Rosales, Zeina E. Jouni, Rosaline Waworuntu
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Publication number: 20130017293Abstract: A nutritional composition for improving the immunological function of a subject, including a lipid or fat; a protein source; about 5 to about 100 mg/100 kcal of a source of long chain polyunsaturated fatty acids which comprises docosahexanoic acid; and about 0.1 to about 1 mg/100 kcal of a prebiotic composition, wherein the prebiotic composition comprises at least 20% of an oligosaccharide which has a fermentation rate which is demonstrably slower than that of galacto-oligosaccharide.Type: ApplicationFiled: September 14, 2012Publication date: January 17, 2013Inventors: Francisco J. Rosales, Eric va Tol, Gyan P. Rai, Kristin Morris, Dattatreya Banavera, Dirk Hondmann, Zeina E. Jouni, Robert J. McMahon, Deborah A. Schade, Donald Carey Walker
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Patent number: 8350006Abstract: A novel method for determining the bioactivity of TGF-? in a sample of milk, raw protein source, or nutritional composition is provided. The method includes particular reconstitution steps, centrifugation steps, incubation steps, and activation steps. The bioactivity of the TGF-? in the sample may be measured in a HT-2 cell bioassay or a cellomics bioassay.Type: GrantFiled: February 13, 2009Date of Patent: January 8, 2013Assignee: Mead Johnson Nutrition CompanyInventors: Gyan P. Rai, Francisco J. Rosales, Zeina E. Jouni, Rosaline Waworuntu
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Patent number: 8293264Abstract: A nutritional formula which includes a lipid or fat; a protein source; about 5 to about 100 mg/100 kcal of a source of long chain polyunsaturated fatty acids which comprises docosahexanoic acid; about 0.1 to about 1 mg/100 kcal of a prebiotic composition, wherein the prebiotic composition comprises at least 20% of an oligosaccharide which comprises galacto-oligosaccharide; and about 0.015 to about 0.1 (pg/?g) ppm of TGF-?.Type: GrantFiled: May 11, 2009Date of Patent: October 23, 2012Assignee: Mead Johnson Nutrition CompanyInventors: Francisco J. Rosales, Eric van Tol, Gyan P. Rai, Dirk Hondmann, Kristin Morris, Dattatreya Banavara, Zeina E. Jouni, Robert J. McMahon, Deborah A. Schade, Donald Carey Walker
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Patent number: 8287931Abstract: A nutritional composition for improving the immunological function of a subject, including a lipid or fat; a protein source; about 5 to about 100 mg/100 kcal of a source of long chain polyunsaturated fatty acids which comprises docosahexanoic acid; and about 0.1 to about 1 mg/100 kcal of a prebiotic composition, wherein the prebiotic composition comprises at least 20% of an oligosaccharide which has a fermentation rate which is demonstrably slower than that of galacto-oligosaccharide.Type: GrantFiled: May 11, 2009Date of Patent: October 16, 2012Assignee: Mead Johnson Nutrition CompanyInventors: Francisco J. Rosales, Eric van Tol, Gyan P. Rai, Kristin Morris, Dattatreya Banavara, Dirk Hondmann, Zeina E. Jouni, Robert J. McMahon, Deborah A. Schade, Donald Carey Walker
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Patent number: 8287932Abstract: A nutritional composition including a lipid or fat; a protein source; at least about 5 mg/100 kcal of a source of long chain polyunsaturated fatty acids which comprises docosahexanoic acid; and at least about 0.2 mg/100 kcal of a prebiotic composition, wherein the prebiotic composition comprises a plurality of oligosaccharides such that the overall fermentation rate profile of the prebiotic composition provides an increased population of beneficial bacteria in the human gut over an extended period of time.Type: GrantFiled: May 11, 2009Date of Patent: October 16, 2012Assignee: Mead Johnson Nutrition CompanyInventors: Francisco J. Rosales, Gyan P. Rai, Kristin Morris, Dattatreya Banavara, Dirk Hondmann, Eric van Tol, Zeina E. Joani, Robert J. McMahon, Deborah A. Schade, Donald Carey Walker
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Patent number: 8075934Abstract: The present invention is directed an improved nutritional composition, methods of improving digestion, and methods of enhancing the bioavailability of TGF-?.Type: GrantFiled: February 13, 2009Date of Patent: December 13, 2011Assignee: Mead Johnson Nutrition CompanyInventors: Dattatreya Banavara, Win-Chin Chiang, Deborah A. Schade, Joaquin A. Franco, Juan M. Gonzalez, Dirk Hondmann, Zeina E. Jouni, Yung-Hsiung Lee, Robert J. McMahon, Kristin Morris, Deshanie Rai, Gyan P. Rai, Nagendra Rangavajla, Francisco J. Rosales, William Michael Russell, Eric Van Tol, Hugh N. Tucker, Donald Carey Walker
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Publication number: 20100284980Abstract: A nutritional formula which includes a lipid or fat; a protein source; about 5 to about 100 mg/100 kcal of a source of long chain polyunsaturated fatty acids which comprises docosahexanoic acid; about 0.1 to about 1 mg/100 kcal of a prebiotic composition, wherein the prebiotic composition comprises at least 20% of an oligosaccharide which comprises galacto-oligosaccharide; and about 0.015 to about 0.1 (pg/?g) ppm of TGF-?.Type: ApplicationFiled: May 11, 2009Publication date: November 11, 2010Inventors: Francisco J. Rosales, Eric van Tol, Gyan P. Rai, Dirk Hondmann, Kirstin Morris, Dattatreya Banavara, Zeina E. Jouni, Robert J. McMahon, Deborah A. Schade, Donald Carey Walker
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Publication number: 20100105615Abstract: A nutritional composition for improving the immunological function of a subject, including a lipid or fat; a protein source; about 5 to about 100 mg/100 kcal of a source of long chain polyunsaturated fatty acids which comprises docosahexanoic acid; and about 0.1 to about 1 mg/100 kcal of a prebiotic composition, wherein the prebiotic composition comprises at least 20% of an oligosaccharide which has a fermentation rate which is demonstrably slower than that of galacto-oligosaccharide.Type: ApplicationFiled: May 11, 2009Publication date: April 29, 2010Inventors: Francisco J. Rosales, Eric van Tol, Gyan P. Rai, Kristin Morris, Dattatreya Banavera, Dirk Hondmann, Zeina E. Jouni, Robert J. McMahon, Deborah A. Schade, Donald Carey Walker
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Publication number: 20100104696Abstract: The present invention is directed an improved nutritional composition, methods of improving digestion, and methods of enhancing the bioavailability of TGF-?.Type: ApplicationFiled: February 13, 2009Publication date: April 29, 2010Applicant: Mead Johnson & Co.Inventors: Dattatreya Banavara, Win-Chin Chiang, Deborah A. Schade, Joaquin A. Franco, Juan M. Gonzalez, Dirk Hondmann, Zeina E. Jouni, Yung-Hsiung Lee, Robert J. McMahon, Kristin Morris, Deshanie Rai, Gyan P. Rai, Nagendra Rangavajla, Francisco J. Rosales, William Michael Russell, Eric Van Tol, Hugh N. Tucker, Donald Carey Walker
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Publication number: 20100105083Abstract: A novel method for determining the levels of TGF-?1 or TGF-?2 in a sample of milk, raw protein source, or nutritional composition is provided. The method involves, in some cases, reconstituting the sample; in some cases, centrifuging the sample; activating the sample using particular ratios of sample:acid:base; diluting the sample using particular ratios of sample:buffer agent; and determining the concentration of TGF-?1 in the sample using an ELISA assay.Type: ApplicationFiled: February 12, 2009Publication date: April 29, 2010Applicant: MEAD JOHNSON & CO.Inventors: Gyan P. Rai, Francisco J. Rosales, Zeina E. Jouni, Rosaline Waworuntu
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Publication number: 20100104545Abstract: A nutritional composition having a lipid or fat; a protein source; a source of long chain polyunsaturated fatty acids which comprises docosahexanoic acid; and up to about 2.5% by weight of a source of supplemental calcium which, when dissociated, provides a cation having prebiotic functionality.Type: ApplicationFiled: May 11, 2009Publication date: April 29, 2010Inventors: Francisco J. Rosales, Gyan P. Rai, Kristin Morris, Dattatreya Banavara, Eric van Tol, Zeina E. Jouni, Robert J. McMahon, Deborah A. Schade, Donald Carey Walker
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Publication number: 20100105080Abstract: A novel method for determining the bioactivity of TGF-? in a sample of milk, raw protein source, or nutritional composition is provided. The method includes particular reconstitution steps, centrifugation steps, incubation steps, and activation steps. The bioactivity of the TGF-? in the sample may be measured in a HT-2 cell bioassay or a cellomics bioassay.Type: ApplicationFiled: February 13, 2009Publication date: April 29, 2010Applicant: MEAD JOHNSON & CO.Inventors: Gyan P. Rai, Francisco J. Rosales, Zeina E. Jouni, Rosaline Waworuntu
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Publication number: 20100104686Abstract: A nutritional composition including a lipid or fat; a protein source; at least about 5 mg/100 kcal of a source of long chain polyunsaturated fatty acids which comprises docosahexanoic acid; and at least about 0.2 mg/100 kcal of a prebiotic composition, wherein the prebiotic composition comprises a plurality of oligosaccharides such that the overall fermentation rate profile of the prebiotic composition provides an increased population of beneficial bacteria in the human gut over an extended period of time.Type: ApplicationFiled: May 11, 2009Publication date: April 29, 2010Inventors: Francisco J. Rosales, Gyan P. Rai, Kristin Morris, Dattatreya Banavara, Dirk Hondmann, Eriv van Tol, Zeina E. Joani, Robert J. McMahon, Deborah A. Schade, Donald Carey Walker